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Q2IZC3 (Q2IZC3_RHOP2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 HAMAP MF_00191
EC=1.17.1.2 HAMAP MF_00191
Gene names
Name:ispH2 HAMAP MF_00191
Ordered Locus Names:RPB_1729
OrganismRhodopseudomonas palustris (strain HaA2) [Complete proteome] [HAMAP] EMBL ABD06437.1
Taxonomic identifier316058 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) By similarity. HAMAP MF_00191

Catalytic activity

Dimethylallyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191

Isopentenyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191

Cofactor

Binds 1 3Fe-4S cluster By similarity. HAMAP MF_00191

Pathway

Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1. HAMAP MF_00191

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6. HAMAP MF_00191

Sequence similarities

Belongs to the IspH family. HAMAP MF_00191

Sequences

Sequence LengthMass (Da)Tools
Q2IZC3 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: 294A227F2A5736BC

FASTA31433,726
        10         20         30         40         50         60 
MSDVRPLEVF LAQPRGFCAG VVRAIEIVER ALEKYGPPVY VRHEIVHNKY VVESLKAKGA 

        70         80         90        100        110        120 
IFVEELSEVP PKAVTVFSAH GVARSIEEEA ASRGLPVLNA TCPLVTKVHN QGKRYTAKGR 

       130        140        150        160        170        180 
TLILIGHAGH PEVEGTMGQV PGPVLLVQNL DDVAALTLPS DTPVAYITQT TLSVDDTRDI 

       190        200        210        220        230        240 
IAALSKRFSD IQGPDTRDIC YATQNRQSAV RAMSKLVDLI LVVGANNSSN SNRLREIGTE 

       250        260        270        280        290        300 
AGIPSYLISD GSELNPDWLE GKKAVGITAG ASAPEVLVDD VIEALRRIVP VSVSVLPGRE 

       310 
ENIEFVLPAE LVTA

« Hide

References

[1]"Complete sequence of Rhodopseudomonas palustris HaA2."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Pelletier D.A. expand/collapse author list , Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HaA2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000250 Genomic DNA. Translation: ABD06437.1.
RefSeqYP_485348.1. NC_007778.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ2IZC3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3908254.
GenomeReviewsGene locus RPB_1729 in contig CP000250_GR.
KEGGrpb:RPB_1729.
PATRIC23298045. VBIRhoPal125544_1816.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0761.
HOGENOMHBG335228.
OMAHNQGKRY.
PhylomeDBQ2IZC3.
ProtClustDBPRK01045.

Enzyme and pathway databases

BioCycRPAL316058:RPB_1729-MONOMER.

Family and domain databases

HAMAPMF_00191. IspH.
[Tree]
InterProIPR003451. LytB.
[Graphical view]
KOK03527.
PfamPF02401. LYTB. 1 hit.
[Graphical view]
TIGRFAMsTIGR00216. IspH_lytB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ2IZC3_RHOP2
AccessionPrimary (citable) accession number: Q2IZC3
Entry history
Integrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info