Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q2IWR7

- Q2IWR7_RHOP2

UniProt

Q2IWR7 - Q2IWR7_RHOP2

Protein

K(+)-insensitive pyrophosphate-energized proton pump

Gene

hppA

Organism
Rhodopseudomonas palustris (strain HaA2)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (07 Mar 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.UniRule annotation

    Catalytic activityi

    Diphosphate + H2O = 2 phosphate.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei465 – 4651Determinant of potassium independenceUniRule annotation

    GO - Molecular functioni

    1. hydrogen-translocating pyrophosphatase activity Source: UniProtKB-HAMAP
    2. inorganic diphosphatase activity Source: UniProtKB-HAMAP
    3. magnesium ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. proton transport Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    HydrolaseUniRule annotationImported

    Keywords - Biological processi

    Hydrogen ion transportUniRule annotation, Ion transport, Transport

    Keywords - Ligandi

    MagnesiumUniRule annotation

    Enzyme and pathway databases

    BioCyciRPAL316058:GHF1-2675-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    K(+)-insensitive pyrophosphate-energized proton pumpUniRule annotation (EC:3.6.1.1UniRule annotation)
    Alternative name(s):
    Membrane-bound proton-translocating pyrophosphataseUniRule annotation
    Pyrophosphate-energized inorganic pyrophosphataseUniRule annotation
    Gene namesi
    Name:hppAUniRule annotation
    Ordered Locus Names:RPB_2641Imported
    OrganismiRhodopseudomonas palustris (strain HaA2)Imported
    Taxonomic identifieri316058 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
    ProteomesiUP000008809: Chromosome

    Subcellular locationi

    Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of plasma membrane Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cell membraneUniRule annotation, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2828 PotentialImportedAdd
    BLAST
    Chaini29 – 707679 PotentialImportedPRO_5000107393Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi316058.RPB_2641.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei1 – 2121Helical;UniRule annotationAdd
    BLAST
    Transmembranei62 – 8221Helical;UniRule annotationAdd
    BLAST
    Transmembranei126 – 14621Helical;UniRule annotationAdd
    BLAST
    Transmembranei164 – 18421Helical;UniRule annotationAdd
    BLAST
    Transmembranei231 – 25121Helical;UniRule annotationAdd
    BLAST
    Transmembranei262 – 28221Helical;UniRule annotationAdd
    BLAST
    Transmembranei299 – 31921Helical;UniRule annotationAdd
    BLAST
    Transmembranei329 – 34921Helical;UniRule annotationAdd
    BLAST
    Transmembranei392 – 41221Helical;UniRule annotationAdd
    BLAST
    Transmembranei413 – 43321Helical;UniRule annotationAdd
    BLAST
    Transmembranei466 – 48621Helical;UniRule annotationAdd
    BLAST
    Transmembranei517 – 53721Helical;UniRule annotationAdd
    BLAST
    Transmembranei586 – 60621Helical;UniRule annotationAdd
    BLAST
    Transmembranei617 – 63721Helical;UniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily. [View classification]UniRule annotation

    Keywords - Domaini

    SignalImported, Transmembrane, Transmembrane helixUniRule annotation

    Phylogenomic databases

    eggNOGiCOG3808.
    HOGENOMiHOG000007098.
    KOiK15987.
    OMAiLYKGLAV.
    OrthoDBiEOG6TXQSF.

    Family and domain databases

    HAMAPiMF_01129. PPase_energized_pump.
    InterProiIPR004131. PPase-energised_H-pump.
    [Graphical view]
    PfamiPF03030. H_PPase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001265. H+-PPase. 1 hit.
    TIGRFAMsiTIGR01104. V_PPase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q2IWR7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTALWVIVLC GALAIVYAVW ATSSVLAADQ GNARMQEIAA AVREGAQAYL    50
    KRQYMTIAIV GVVIFALLAY FLGVLVAIGF LIGAVLSGAA GFIGMNVSVR 100
    ANVRTAQAAT TSLAGGLELA FKAGAITGLL VAGLALLGVT LYFIYLIHYA 150
    NLAPNSRTVV DALVALGFGA SLISIFARLG GGIFTKGADV GGDLVGKVEA 200
    GIPEDDPRNP ATIADNVGDN VGDCAGMAAD LFETYAVTAV ATMVLAAIFF 250
    AATPDLLLNM MTLPLAIGGI CILTSIAGTF FVKLGASQSI MGALYKGLIA 300
    TGVLSLIGVG AVIHQLIGFG PLAGVSYTGL ALFECGIVGL AVTGLIIWIT 350
    EYYTGTDYRP VKSIAQSSVT GHGTNVIQGL AISMESTALP AIVIIAGILV 400
    TYSLAGLFGI AIATTTMLAL AGMIVALDAF GPVTDNAGGI AEMAGLPKEV 450
    RKATDALDAV GNTTKAVTKG YAIGSAGLGA LVLFAAYNED LKFFIANAAK 500
    YPYFEGVLPD FSLNNPYVVV GLLFGGLLPY LFGAMGMTAV GRAAGAIVEE 550
    VRRQFREKPG IMKGTDKPDY GKAVDLLTKA AIKEMIIPSL LPVLSPIFVY 600
    FVIYAIAGGG PAGKSAAFSA VGAMLLGVIV TGLFVAISMT SGGGAWDNAK 650
    KYIEDGHHGG KGSDAHKAAV TGDTVGDPYK DTAGPAVNPM IKITNIVALL 700
    LLAILAH 707
    Length:707
    Mass (Da):72,241
    Last modified:March 7, 2006 - v1
    Checksum:i4FC5AE83E996CB60
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000250 Genomic DNA. Translation: ABD07343.1.
    RefSeqiWP_011441528.1. NC_007778.1.
    YP_486254.1. NC_007778.1.

    Genome annotation databases

    EnsemblBacteriaiABD07343; ABD07343; RPB_2641.
    GeneIDi3910433.
    KEGGirpb:RPB_2641.
    PATRICi23299997. VBIRhoPal125544_2781.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000250 Genomic DNA. Translation: ABD07343.1 .
    RefSeqi WP_011441528.1. NC_007778.1.
    YP_486254.1. NC_007778.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 316058.RPB_2641.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABD07343 ; ABD07343 ; RPB_2641 .
    GeneIDi 3910433.
    KEGGi rpb:RPB_2641.
    PATRICi 23299997. VBIRhoPal125544_2781.

    Phylogenomic databases

    eggNOGi COG3808.
    HOGENOMi HOG000007098.
    KOi K15987.
    OMAi LYKGLAV.
    OrthoDBi EOG6TXQSF.

    Enzyme and pathway databases

    BioCyci RPAL316058:GHF1-2675-MONOMER.

    Family and domain databases

    HAMAPi MF_01129. PPase_energized_pump.
    InterProi IPR004131. PPase-energised_H-pump.
    [Graphical view ]
    Pfami PF03030. H_PPase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001265. H+-PPase. 1 hit.
    TIGRFAMsi TIGR01104. V_PPase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HaA2Imported.

    Entry informationi

    Entry nameiQ2IWR7_RHOP2
    AccessioniPrimary (citable) accession number: Q2IWR7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 7, 2006
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3