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Q2IWR7

- Q2IWR7_RHOP2

UniProt

Q2IWR7 - Q2IWR7_RHOP2

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Protein
K(+)-insensitive pyrophosphate-energized proton pump
Gene
hppA, RPB_2641
Organism
Rhodopseudomonas palustris (strain HaA2)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force By similarity.UniRule annotation

Catalytic activityi

Diphosphate + H2O = 2 phosphate.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei465 – 4651Determinant of potassium independence By similarityUniRule annotation

GO - Molecular functioni

  1. hydrogen-translocating pyrophosphatase activity Source: UniProtKB-HAMAP
  2. inorganic diphosphatase activity Source: UniProtKB-HAMAP
  3. magnesium ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. proton transport Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationImported

Keywords - Biological processi

Hydrogen ion transportUniRule annotation, Ion transport, Transport

Keywords - Ligandi

MagnesiumUniRule annotation

Enzyme and pathway databases

BioCyciRPAL316058:GHF1-2675-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
K(+)-insensitive pyrophosphate-energized proton pumpUniRule annotation (EC:3.6.1.1UniRule annotation)
Alternative name(s):
Membrane-bound proton-translocating pyrophosphatase
Pyrophosphate-energized inorganic pyrophosphatase
Gene namesi
Name:hppAUniRule annotation
Ordered Locus Names:RPB_2641Imported
OrganismiRhodopseudomonas palustris (strain HaA2)Imported
Taxonomic identifieri316058 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
ProteomesiUP000008809: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei62 – 8221Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei126 – 14621Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei164 – 18421Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei231 – 25121Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei262 – 28221Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei299 – 31921Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei329 – 34921Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei392 – 41221Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei413 – 43321Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei466 – 48621Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei517 – 53721Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei586 – 60621Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei617 – 63721Helical; By similarityUniRule annotation
Add
BLAST

GO - Cellular componenti

  1. integral component of plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2828 PredictedImported
Add
BLAST
Chaini29 – 707679 PredictedImported
PRO_5000107393Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi316058.RPB_2641.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

SignalImported, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiCOG3808.
HOGENOMiHOG000007098.
KOiK15987.
OMAiLYKGLAV.
OrthoDBiEOG6TXQSF.

Family and domain databases

HAMAPiMF_01129. PPase_energized_pump.
InterProiIPR004131. PPase-energised_H-pump.
[Graphical view]
PfamiPF03030. H_PPase. 1 hit.
[Graphical view]
PIRSFiPIRSF001265. H+-PPase. 1 hit.
TIGRFAMsiTIGR01104. V_PPase. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2IWR7-1 [UniParc]FASTAAdd to Basket

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MTALWVIVLC GALAIVYAVW ATSSVLAADQ GNARMQEIAA AVREGAQAYL    50
KRQYMTIAIV GVVIFALLAY FLGVLVAIGF LIGAVLSGAA GFIGMNVSVR 100
ANVRTAQAAT TSLAGGLELA FKAGAITGLL VAGLALLGVT LYFIYLIHYA 150
NLAPNSRTVV DALVALGFGA SLISIFARLG GGIFTKGADV GGDLVGKVEA 200
GIPEDDPRNP ATIADNVGDN VGDCAGMAAD LFETYAVTAV ATMVLAAIFF 250
AATPDLLLNM MTLPLAIGGI CILTSIAGTF FVKLGASQSI MGALYKGLIA 300
TGVLSLIGVG AVIHQLIGFG PLAGVSYTGL ALFECGIVGL AVTGLIIWIT 350
EYYTGTDYRP VKSIAQSSVT GHGTNVIQGL AISMESTALP AIVIIAGILV 400
TYSLAGLFGI AIATTTMLAL AGMIVALDAF GPVTDNAGGI AEMAGLPKEV 450
RKATDALDAV GNTTKAVTKG YAIGSAGLGA LVLFAAYNED LKFFIANAAK 500
YPYFEGVLPD FSLNNPYVVV GLLFGGLLPY LFGAMGMTAV GRAAGAIVEE 550
VRRQFREKPG IMKGTDKPDY GKAVDLLTKA AIKEMIIPSL LPVLSPIFVY 600
FVIYAIAGGG PAGKSAAFSA VGAMLLGVIV TGLFVAISMT SGGGAWDNAK 650
KYIEDGHHGG KGSDAHKAAV TGDTVGDPYK DTAGPAVNPM IKITNIVALL 700
LLAILAH 707
Length:707
Mass (Da):72,241
Last modified:March 7, 2006 - v1
Checksum:i4FC5AE83E996CB60
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000250 Genomic DNA. Translation: ABD07343.1.
RefSeqiWP_011441528.1. NC_007778.1.
YP_486254.1. NC_007778.1.

Genome annotation databases

EnsemblBacteriaiABD07343; ABD07343; RPB_2641.
GeneIDi3910433.
KEGGirpb:RPB_2641.
PATRICi23299997. VBIRhoPal125544_2781.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000250 Genomic DNA. Translation: ABD07343.1 .
RefSeqi WP_011441528.1. NC_007778.1.
YP_486254.1. NC_007778.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 316058.RPB_2641.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABD07343 ; ABD07343 ; RPB_2641 .
GeneIDi 3910433.
KEGGi rpb:RPB_2641.
PATRICi 23299997. VBIRhoPal125544_2781.

Phylogenomic databases

eggNOGi COG3808.
HOGENOMi HOG000007098.
KOi K15987.
OMAi LYKGLAV.
OrthoDBi EOG6TXQSF.

Enzyme and pathway databases

BioCyci RPAL316058:GHF1-2675-MONOMER.

Family and domain databases

HAMAPi MF_01129. PPase_energized_pump.
InterProi IPR004131. PPase-energised_H-pump.
[Graphical view ]
Pfami PF03030. H_PPase. 1 hit.
[Graphical view ]
PIRSFi PIRSF001265. H+-PPase. 1 hit.
TIGRFAMsi TIGR01104. V_PPase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HaA2Imported.

Entry informationi

Entry nameiQ2IWR7_RHOP2
AccessioniPrimary (citable) accession number: Q2IWR7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: September 3, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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