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Q2IW93

- LPXB_RHOP2

UniProt

Q2IW93 - LPXB_RHOP2

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Rhodopseudomonas palustris (strain HaA2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (07 Mar 2006)
      Previous versions | rss
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    Functioni

    Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

    Catalytic activityi

    UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. lipid A biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

    Enzyme and pathway databases

    BioCyciRPAL316058:GHF1-2850-MONOMER.
    UniPathwayiUPA00359; UER00481.

    Protein family/group databases

    CAZyiGT19. Glycosyltransferase Family 19.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
    Gene namesi
    Name:lpxBUniRule annotation
    Ordered Locus Names:RPB_2815
    OrganismiRhodopseudomonas palustris (strain HaA2)
    Taxonomic identifieri316058 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
    ProteomesiUP000008809: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 393393Lipid-A-disaccharide synthasePRO_0000255216Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi316058.RPB_2815.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2IW93.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LpxB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0763.
    HOGENOMiHOG000018004.
    KOiK00748.
    OMAiVSPITYR.
    OrthoDBiEOG6FBWZR.

    Family and domain databases

    HAMAPiMF_00392. LpxB.
    InterProiIPR003835. Glyco_trans_19.
    [Graphical view]
    PfamiPF02684. LpxB. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00215. lpxB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2IW93-1 [UniParc]FASTAAdd to Basket

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    MRAANATTGA VRRLFLIATE ESGDRLGAAL MQALKTRLGD GVVFEGVGGR    50
    AMAEQGLVSL FPIEELSIMG ISAVVRRLPS ILRRIRSTAD AVLGAKPDML 100
    IIIDSPDFTH RVARRVRVRD PSIAIVNYVS PTVWAWRPGR ARAMRRYVDH 150
    VLALLPFEPE EYRRLRGPPC TYVGHPLTEQ IAHLRPSPAE QARRDAEPPV 200
    LVVLPGSRRS EIHHLMAVFG ETLGRLQAEQ GDLELILPTV PHLRDAVEAG 250
    VRDWPVQPRI VVGDADKKAA FRIARAAFAK SGTVTLELAL AHVPMVAVYK 300
    AGAMEAWIGK RVIRSASVIL ANLVVGENVI PEFIQEDCVP DRLVPALREV 350
    LADTPMRARQ LEGFGRIDDI MSTGAQTPSG RAADIVLNVL RKH 393
    Length:393
    Mass (Da):43,078
    Last modified:March 7, 2006 - v1
    Checksum:i88C53894FD534D7D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000250 Genomic DNA. Translation: ABD07517.1.
    RefSeqiWP_011441702.1. NC_007778.1.
    YP_486428.1. NC_007778.1.

    Genome annotation databases

    EnsemblBacteriaiABD07517; ABD07517; RPB_2815.
    GeneIDi3910608.
    KEGGirpb:RPB_2815.
    PATRICi23300369. VBIRhoPal125544_2966.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000250 Genomic DNA. Translation: ABD07517.1 .
    RefSeqi WP_011441702.1. NC_007778.1.
    YP_486428.1. NC_007778.1.

    3D structure databases

    ProteinModelPortali Q2IW93.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 316058.RPB_2815.

    Protein family/group databases

    CAZyi GT19. Glycosyltransferase Family 19.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABD07517 ; ABD07517 ; RPB_2815 .
    GeneIDi 3910608.
    KEGGi rpb:RPB_2815.
    PATRICi 23300369. VBIRhoPal125544_2966.

    Phylogenomic databases

    eggNOGi COG0763.
    HOGENOMi HOG000018004.
    KOi K00748.
    OMAi VSPITYR.
    OrthoDBi EOG6FBWZR.

    Enzyme and pathway databases

    UniPathwayi UPA00359 ; UER00481 .
    BioCyci RPAL316058:GHF1-2850-MONOMER.

    Family and domain databases

    HAMAPi MF_00392. LpxB.
    InterProi IPR003835. Glyco_trans_19.
    [Graphical view ]
    Pfami PF02684. LpxB. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00215. lpxB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HaA2.

    Entry informationi

    Entry nameiLPXB_RHOP2
    AccessioniPrimary (citable) accession number: Q2IW93
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3