Reviewed, UniProtKB/Swiss-Prot Q2IQJ6 (SYGA_ANADE)

Names and origin

Protein names

Recommended name:
    Glycyl-tRNA synthetase alpha subunit
    EC=6.1.1.14
Alternative name(s):
    Glycine--tRNA ligase alpha subunit
      Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	Adeh_1305

Organism

Anaeromyxobacter dehalogenans (strain 2CP-C) [Complete proteome] [HAMAP]

Taxonomic identifier

290397 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Cystobacterineae › Myxococcaceae › Anaeromyxobacter

Protein attributes

Sequence length	309 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00254
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 309	309	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_1000047395

Sequences

	Sequence		Length	Mass (Da)
	Q2IQJ6-1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: C997716B21ED4CF5	FASTA	309	35,324
	10 20 30 40 50 60 MYFQDLILKL QSYWASRNCI LAQGYDQEVG AGTMNPSTFL RVLGPEPWNV AYVEPSRRPA 70 80 90 100 110 120 DGRYGENPNR LYQHHQFQVI LKPNPPDVQE LYLGSLRAIG IDPREHDIRF VEDDWESPTL 130 140 150 160 170 180 GAWGLGWEVW CDGMEITQYT YFQQAGGFEV KPVAAELTYG LERIAMYLQD VENVFDVEWV 190 200 210 220 230 240 KGVKYREVFH RNEVEMSTYS FQASDPKMLF GLFDTYEAEC KRLIGLKLPL PAYDYCLKCS 250 260 270 280 290 300 HAFNNLDARG AISVTERAAY IGRVRALAHD CAKGYLDSRE ALGFPLLPPA DRKQAVEAAR AAREARESR

References

[1]

"Complete sequence of Anaeromyxobacter dehalogenans 2CP-C." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. , Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S., Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P. Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000251 Genomic DNA. Translation: ABC81079.1.
RefSeq	YP_464516.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3888660.
GenomeReviews	Gene locus Adeh_1305 in contig CP000251_GR.
KEGG	ade:Adeh_1305.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2IQJ6.
OMA	Q2IQJ6. CRRPTDG.
Enzyme and pathway databases
BioCyc	ADEH290397:ADEH_1305-MON.
Family and domain databases
HAMAP	MF_00254. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
ProDom	PD006985. tRNA_synt_2e. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_ANADE

Accession

Primary (citable) accession number: Q2IQJ6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	March 7, 2006
Last modified:	June 16, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)