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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Anaeromyxobacter dehalogenans (strain 2CP-C)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolase (EC:3.1.1.29)
Short name:
PTH
Gene namesi
Name:pth
Ordered Locus Names:Adeh_0119
OrganismiAnaeromyxobacter dehalogenans (strain 2CP-C)
Taxonomic identifieri290397 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeAnaeromyxobacteraceaeAnaeromyxobacter
Proteomesi
  • UP000001935 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002640031 – 192Peptidyl-tRNA hydrolaseAdd BLAST192

Interactioni

Subunit structurei

Monomer.

Protein-protein interaction databases

STRINGi290397.Adeh_0119.

Structurei

3D structure databases

ProteinModelPortaliQ2IM62.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.

Phylogenomic databases

eggNOGiENOG4108ZPD. Bacteria.
COG0193. LUCA.
HOGENOMiHOG000004797.
KOiK01056.
OMAiRYAHTRH.

Family and domain databases

CDDicd00462. PTH. 1 hit.
Gene3Di3.40.50.1470. 1 hit.
HAMAPiMF_00083. Pept_tRNA_hydro_bact. 1 hit.
InterProiView protein in InterPro
IPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
IPR036416. Pept_tRNA_hydro_sf.
PANTHERiPTHR17224. PTHR17224. 1 hit.
PfamiView protein in Pfam
PF01195. Pept_tRNA_hydro. 1 hit.
SUPFAMiSSF53178. SSF53178. 1 hit.
TIGRFAMsiTIGR00447. pth. 1 hit.
PROSITEiView protein in PROSITE
PS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2IM62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLVVGLGNP GEEYARTRHN VGFVVADRLA QLAGASFTAK KFAAELAEAR
60 70 80 90 100
LGPERVWILK PQTYMNHSGE AVGAALRFWK LGLDDLVVVH DDLELEPFRV
110 120 130 140 150
QLKVGGGHGG HNGVKSVNAH VGSPEYARVR VGVGRPPPRM DPADYVLGKF
160 170 180 190
AKGEDAELDL CVEQAVEATR LAVELGAAKA MNQVNRRSRA AE
Length:192
Mass (Da):20,717
Last modified:March 7, 2006 - v1
Checksum:i442847C4A5D3024E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000251 Genomic DNA. Translation: ABC79896.1.
RefSeqiWP_011419179.1. NC_007760.1.

Genome annotation databases

EnsemblBacteriaiABC79896; ABC79896; Adeh_0119.
KEGGiade:Adeh_0119.

Similar proteinsi

Entry informationi

Entry nameiPTH_ANADE
AccessioniPrimary (citable) accession number: Q2IM62
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: March 7, 2006
Last modified: October 25, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families