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Q2IKN7

- Q2IKN7_ANADE

UniProt

Q2IKN7 - Q2IKN7_ANADE

Protein
Submitted name:

D-alanine--D-alanine ligase

Gene

Adeh_2449

Organism
Anaeromyxobacter dehalogenans (strain 2CP-C)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (07 Mar 2006)
      Previous versions | rss
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    Functioni

    Cell wall formation.SAAS annotation

    Catalytic activityi

    ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
    2. regulation of cell shape Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseSAAS annotationImported

    Keywords - Biological processi

    Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

    Keywords - Ligandi

    ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciADEH290397:GI2Z-2480-MONOMER.
    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
    Gene namesi
    Ordered Locus Names:Adeh_2449Imported
    OrganismiAnaeromyxobacter dehalogenans (strain 2CP-C)Imported
    Taxonomic identifieri290397 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeAnaeromyxobacteraceaeAnaeromyxobacter
    ProteomesiUP000001935: Chromosome

    Subcellular locationi

    Cytoplasm SAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi290397.Adeh_2449.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2IKN7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains ATP-grasp domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG1181.
    HOGENOMiHOG000002979.
    KOiK01921.
    OMAiYFLEINA.
    OrthoDBiEOG66MQKK.

    Family and domain databases

    Gene3Di3.30.1490.20. 2 hits.
    3.30.470.20. 2 hits.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR016185. PreATP-grasp_dom.
    [Graphical view]
    PANTHERiPTHR23132. PTHR23132. 1 hit.
    PfamiPF07478. Dala_Dala_lig_C. 2 hits.
    [Graphical view]
    SUPFAMiSSF52440. SSF52440. 2 hits.
    PROSITEiPS50975. ATP_GRASP. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2IKN7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRIALTHNLR ISDSEEEAEF DTRETVDALA GAIERLGHRV ERIEVSGPAS    50
    RTVTRLEAFG PDLIFNTAEG RRGRFREAFF PALFDELGMP YTGSDAYALA 100
    VTLDKQLTKL VLAQKGVRTP RWQYVEEPWQ LQVNALRYPV IVKPNFEGSS 150
    KGITQDSVVD DPVRLHEVVQ DGLARYPAGL LVEEFVVGRD LTVPFLEAAA 200
    PDRHGVLQPV EYVIDPAVTA GRKYAIYDYE LKTKLDKAVS VRAPAKVKRA 250
    QAERIQQLCE TVYRELGIRD LGRIDLRLGD DGELYFLEIN ALPSLEPGAG 300
    IYAAAALEGL HEDAVLGAVI QSAVQRWNIV DKSARRGRPR RTERLKVGFS 350
    FNVKRVTPDP GGEQDEEAEY DSPKTLQAIR EAIASWGHEV VDLEATQDLP 400
    LQLASTPVDV VFNIAEGFKG RSRESQVPSL LELLDIPYTG SDPSALSVSL 450
    DKALAKRMVR THGILTPDYL VLNTGNERLP RELTFPLIVK PVAEGTSKGV 500
    TRKSVVRDEL ELREVARELI AKYRQPALAE GYVSGREFTV GLLGERRPRV 550
    LPPMEIVFLD AKDPTPIYSF EMKQDWSERI RYEVPAKLSP RELDRLEKAA 600
    RECFTALGCR DVARLDFRMD AEGRIHFIEC NPLPGLAPGW SDLVLIAQAA 650
    GMDYRGLIGE ILSFAIRRYQ ERERERERAR RAQAAAEREA QASAPANGAP 700
    GGESPAGGNG GAGGEAGERR PQAPHRH 727
    Length:727
    Mass (Da):80,700
    Last modified:March 7, 2006 - v1
    Checksum:i4704C10BCF537848
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000251 Genomic DNA. Translation: ABC82219.1.
    RefSeqiYP_465656.1. NC_007760.1.

    Genome annotation databases

    EnsemblBacteriaiABC82219; ABC82219; Adeh_2449.
    GeneIDi3889782.
    KEGGiade:Adeh_2449.
    PATRICi20921063. VBIAnaDeh31384_2509.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000251 Genomic DNA. Translation: ABC82219.1 .
    RefSeqi YP_465656.1. NC_007760.1.

    3D structure databases

    ProteinModelPortali Q2IKN7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 290397.Adeh_2449.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABC82219 ; ABC82219 ; Adeh_2449 .
    GeneIDi 3889782.
    KEGGi ade:Adeh_2449.
    PATRICi 20921063. VBIAnaDeh31384_2509.

    Phylogenomic databases

    eggNOGi COG1181.
    HOGENOMi HOG000002979.
    KOi K01921.
    OMAi YFLEINA.
    OrthoDBi EOG66MQKK.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci ADEH290397:GI2Z-2480-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 2 hits.
    3.30.470.20. 2 hits.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR016185. PreATP-grasp_dom.
    [Graphical view ]
    PANTHERi PTHR23132. PTHR23132. 1 hit.
    Pfami PF07478. Dala_Dala_lig_C. 2 hits.
    [Graphical view ]
    SUPFAMi SSF52440. SSF52440. 2 hits.
    PROSITEi PS50975. ATP_GRASP. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 2CP-CImported.

    Entry informationi

    Entry nameiQ2IKN7_ANADE
    AccessioniPrimary (citable) accession number: Q2IKN7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 7, 2006
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3