SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q2IKN7

- Q2IKN7_ANADE

UniProt

Q2IKN7 - Q2IKN7_ANADE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: D-alanine--D-alanine ligase
Gene
Adeh_2449
Organism
Anaeromyxobacter dehalogenans (strain 2CP-C)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Cell wall formation By similarity.SAAS annotations

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotations

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.SAAS annotations

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
  2. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationsImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotations, Peptidoglycan synthesisSAAS annotations

Keywords - Ligandi

ATP-bindingSAAS annotations, MagnesiumSAAS annotations, ManganeseSAAS annotations, Metal-bindingSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciADEH290397:GI2Z-2480-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
Gene namesi
Ordered Locus Names:Adeh_2449Imported
OrganismiAnaeromyxobacter dehalogenans (strain 2CP-C)Imported
Taxonomic identifieri290397 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeAnaeromyxobacter
ProteomesiUP000001935: Chromosome

Subcellular locationi

Cytoplasm By similarity SAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotations

Interactioni

Protein-protein interaction databases

STRINGi290397.Adeh_2449.

Structurei

3D structure databases

ProteinModelPortaliQ2IKN7.

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotations

Phylogenomic databases

eggNOGiCOG1181.
HOGENOMiHOG000002979.
KOiK01921.
OMAiYFLEINA.
OrthoDBiEOG66MQKK.

Family and domain databases

Gene3Di3.30.1490.20. 2 hits.
3.30.470.20. 2 hits.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 2 hits.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 2 hits.
PROSITEiPS50975. ATP_GRASP. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2IKN7-1 [UniParc]FASTAAdd to Basket

« Hide

MRIALTHNLR ISDSEEEAEF DTRETVDALA GAIERLGHRV ERIEVSGPAS    50
RTVTRLEAFG PDLIFNTAEG RRGRFREAFF PALFDELGMP YTGSDAYALA 100
VTLDKQLTKL VLAQKGVRTP RWQYVEEPWQ LQVNALRYPV IVKPNFEGSS 150
KGITQDSVVD DPVRLHEVVQ DGLARYPAGL LVEEFVVGRD LTVPFLEAAA 200
PDRHGVLQPV EYVIDPAVTA GRKYAIYDYE LKTKLDKAVS VRAPAKVKRA 250
QAERIQQLCE TVYRELGIRD LGRIDLRLGD DGELYFLEIN ALPSLEPGAG 300
IYAAAALEGL HEDAVLGAVI QSAVQRWNIV DKSARRGRPR RTERLKVGFS 350
FNVKRVTPDP GGEQDEEAEY DSPKTLQAIR EAIASWGHEV VDLEATQDLP 400
LQLASTPVDV VFNIAEGFKG RSRESQVPSL LELLDIPYTG SDPSALSVSL 450
DKALAKRMVR THGILTPDYL VLNTGNERLP RELTFPLIVK PVAEGTSKGV 500
TRKSVVRDEL ELREVARELI AKYRQPALAE GYVSGREFTV GLLGERRPRV 550
LPPMEIVFLD AKDPTPIYSF EMKQDWSERI RYEVPAKLSP RELDRLEKAA 600
RECFTALGCR DVARLDFRMD AEGRIHFIEC NPLPGLAPGW SDLVLIAQAA 650
GMDYRGLIGE ILSFAIRRYQ ERERERERAR RAQAAAEREA QASAPANGAP 700
GGESPAGGNG GAGGEAGERR PQAPHRH 727
Length:727
Mass (Da):80,700
Last modified:March 7, 2006 - v1
Checksum:i4704C10BCF537848
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000251 Genomic DNA. Translation: ABC82219.1.
RefSeqiYP_465656.1. NC_007760.1.

Genome annotation databases

EnsemblBacteriaiABC82219; ABC82219; Adeh_2449.
GeneIDi3889782.
KEGGiade:Adeh_2449.
PATRICi20921063. VBIAnaDeh31384_2509.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000251 Genomic DNA. Translation: ABC82219.1 .
RefSeqi YP_465656.1. NC_007760.1.

3D structure databases

ProteinModelPortali Q2IKN7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290397.Adeh_2449.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABC82219 ; ABC82219 ; Adeh_2449 .
GeneIDi 3889782.
KEGGi ade:Adeh_2449.
PATRICi 20921063. VBIAnaDeh31384_2509.

Phylogenomic databases

eggNOGi COG1181.
HOGENOMi HOG000002979.
KOi K01921.
OMAi YFLEINA.
OrthoDBi EOG66MQKK.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci ADEH290397:GI2Z-2480-MONOMER.

Family and domain databases

Gene3Di 3.30.1490.20. 2 hits.
3.30.470.20. 2 hits.
InterProi IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view ]
PANTHERi PTHR23132. PTHR23132. 1 hit.
Pfami PF07478. Dala_Dala_lig_C. 2 hits.
[Graphical view ]
SUPFAMi SSF52440. SSF52440. 2 hits.
PROSITEi PS50975. ATP_GRASP. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2CP-C.

Entry informationi

Entry nameiQ2IKN7_ANADE
AccessioniPrimary (citable) accession number: Q2IKN7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: May 14, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi