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Q2II78

- EFTU_ANADE

UniProt

Q2II78 - EFTU_ANADE

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Protein

Elongation factor Tu

Gene
tuf1, Adeh_1584
tuf2, Adeh_1947
Organism
Anaeromyxobacter dehalogenans (strain 2CP-C)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarity
Nucleotide bindingi81 – 855GTP By similarity
Nucleotide bindingi136 – 1394GTP By similarity

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciADEH290397:GI2Z-1607-MONOMER.
ADEH290397:GI2Z-1975-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor Tu
Short name:
EF-Tu
Gene namesi
Name:tuf1
Ordered Locus Names:Adeh_1584
AND
Name:tuf2
Ordered Locus Names:Adeh_1947
OrganismiAnaeromyxobacter dehalogenans (strain 2CP-C)
Taxonomic identifieri290397 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeAnaeromyxobacter
ProteomesiUP000001935: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 396396Elongation factor TuUniRule annotationPRO_0000337313Add
BLAST

Proteomic databases

PRIDEiQ2II78.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi290397.Adeh_1947.

Structurei

3D structure databases

ProteinModelPortaliQ2II78.
SMRiQ2II78. Positions 2-395.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 206197tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni19 – 268G1 By similarity
Regioni60 – 645G2 By similarity
Regioni81 – 844G3 By similarity
Regioni136 – 1394G4 By similarity
Regioni174 – 1763G5 By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
KOiK02358.
OMAiISAPAAC.
OrthoDBiEOG6R5C6X.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2II78-1 [UniParc]FASTAAdd to Basket

« Hide

MAKEKFERSK PHVNVGTIGH VDHGKTTLTA AITKVLAQKG GAQFLAYDQI    50
DKAPEERERG ITIATAHVEY QTEKRHYAHV DCPGHADYVK NMITGAAQMD 100
GAILVVSAAD GPMPQTREHI LLARQVGVPY IVVFLNKVDM VDDKELLDLV 150
ELEVRELLSE YDFPGNEIPI VKGSALKALE GDKGELGEQA IFKLMEAVDA 200
YIPTPQRATD KPFLMPVEDV FSISGRGTVA TGRVERGIVK VGEEVEVVGL 250
KATAKTVVTG VEMFRKLLDE GRAGDNIGAL LRGLKREEVE RGQVLAKPGS 300
ITPHTKFKAE VYVLTKEEGG RHTPFFNGYR PQFYFRTTDV TGSVQLPQGV 350
EMVMPGDNIG MEVELITPIA MEKELRFAIR EGGRTVGAGV VAEVIQ 396
Length:396
Mass (Da):43,331
Last modified:March 7, 2006 - v1
Checksum:i888CE245F25A4F4F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000251 Genomic DNA. Translation: ABC81357.1.
CP000251 Genomic DNA. Translation: ABC81718.1.
RefSeqiYP_464794.1. NC_007760.1.
YP_465155.1. NC_007760.1.

Genome annotation databases

EnsemblBacteriaiABC81357; ABC81357; Adeh_1584.
ABC81718; ABC81718; Adeh_1947.
GeneIDi3887228.
3887832.
KEGGiade:Adeh_1584.
ade:Adeh_1947.
PATRICi20919307. VBIAnaDeh31384_1637.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000251 Genomic DNA. Translation: ABC81357.1 .
CP000251 Genomic DNA. Translation: ABC81718.1 .
RefSeqi YP_464794.1. NC_007760.1.
YP_465155.1. NC_007760.1.

3D structure databases

ProteinModelPortali Q2II78.
SMRi Q2II78. Positions 2-395.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290397.Adeh_1947.

Proteomic databases

PRIDEi Q2II78.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABC81357 ; ABC81357 ; Adeh_1584 .
ABC81718 ; ABC81718 ; Adeh_1947 .
GeneIDi 3887228.
3887832.
KEGGi ade:Adeh_1584.
ade:Adeh_1947.
PATRICi 20919307. VBIAnaDeh31384_1637.

Phylogenomic databases

eggNOGi COG0050.
HOGENOMi HOG000229290.
KOi K02358.
OMAi ISAPAAC.
OrthoDBi EOG6R5C6X.

Enzyme and pathway databases

BioCyci ADEH290397:GI2Z-1607-MONOMER.
ADEH290397:GI2Z-1975-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2CP-C.

Entry informationi

Entry nameiEFTU_ANADE
AccessioniPrimary (citable) accession number: Q2II78
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 7, 2006
Last modified: September 3, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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