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Q2II39

- Q2II39_ANADE

UniProt

Q2II39 - Q2II39_ANADE

Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Anaeromyxobacter dehalogenans (strain 2CP-C)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (07 Mar 2006)
      Previous versions | rss
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    Functioni

    Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotationSAAS annotation

    Catalytic activityi

    tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei53 – 531NucleophileUniRule annotation
    Binding sitei111 – 1111SubstrateUniRule annotation

    GO - Molecular functioni

    1. lyase activity Source: UniProtKB-KW
    2. pseudouridine synthase activity Source: UniProtKB-HAMAP
    3. RNA binding Source: InterPro

    GO - Biological processi

    1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation, LyaseImported

    Keywords - Biological processi

    tRNA processingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciADEH290397:GI2Z-1562-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
    Alternative name(s):
    tRNA pseudouridine(38-40) synthaseUniRule annotation
    tRNA pseudouridylate synthase IUniRule annotation
    tRNA-uridine isomerase IUniRule annotation
    Gene namesi
    Name:truAUniRule annotation
    Ordered Locus Names:Adeh_1544Imported
    OrganismiAnaeromyxobacter dehalogenans (strain 2CP-C)Imported
    Taxonomic identifieri290397 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeAnaeromyxobacteraceaeAnaeromyxobacter
    ProteomesiUP000001935: Chromosome

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi290397.Adeh_1544.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2II39.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0101.
    HOGENOMiHOG000248674.
    KOiK06173.
    OMAiPDARAFP.
    OrthoDBiEOG6Z9B4R.

    Family and domain databases

    Gene3Di3.30.70.580. 1 hit.
    3.30.70.660. 1 hit.
    HAMAPiMF_00171. TruA.
    InterProiIPR020103. PsdUridine_synth_cat_dom.
    IPR001406. PsdUridine_synth_TruA.
    IPR020097. PsdUridine_synth_TruA_a/b_dom.
    IPR020095. PsdUridine_synth_TruA_C.
    IPR020094. PsdUridine_synth_TruA_N.
    [Graphical view]
    PANTHERiPTHR11142. PTHR11142. 1 hit.
    PfamiPF01416. PseudoU_synth_1. 2 hits.
    [Graphical view]
    PIRSFiPIRSF001430. tRNA_psdUrid_synth. 1 hit.
    SUPFAMiSSF55120. SSF55120. 1 hit.
    TIGRFAMsiTIGR00071. hisT_truA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2II39-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERRSYALRL AYDGGRFRGF QRQPGLPTVQ QALEEALERL GVRAQLHVAA    50
    RTDAGVHALA QVVSFSARAA LDPAALRRGL NEGLPEGILV LDAARVGPSF 100
    HARGSAASRT YVYLVGAPPP EGLRPYAWTL PDARAFPELA EVPPLDAAAM 150
    REALGAAVGE HDFVGFARPG EQRGTVRTLL RAEVVEAGWA PLVAVVLEGK 200
    GFLRAMVRNL VGTAVAVGLG RAPPDVIRTL LATRGRYRGV RAPGWGLTLA 250
    AVRYPDGAWP SPAAPPDPAA SR 272
    Length:272
    Mass (Da):28,851
    Last modified:March 7, 2006 - v1
    Checksum:i3F9044D34321EA21
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000251 Genomic DNA. Translation: ABC81317.1.
    RefSeqiWP_011420600.1. NC_007760.1.
    YP_464754.1. NC_007760.1.

    Genome annotation databases

    EnsemblBacteriaiABC81317; ABC81317; Adeh_1544.
    GeneIDi3888071.
    KEGGiade:Adeh_1544.
    PATRICi20919211. VBIAnaDeh31384_1594.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000251 Genomic DNA. Translation: ABC81317.1 .
    RefSeqi WP_011420600.1. NC_007760.1.
    YP_464754.1. NC_007760.1.

    3D structure databases

    ProteinModelPortali Q2II39.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 290397.Adeh_1544.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABC81317 ; ABC81317 ; Adeh_1544 .
    GeneIDi 3888071.
    KEGGi ade:Adeh_1544.
    PATRICi 20919211. VBIAnaDeh31384_1594.

    Phylogenomic databases

    eggNOGi COG0101.
    HOGENOMi HOG000248674.
    KOi K06173.
    OMAi PDARAFP.
    OrthoDBi EOG6Z9B4R.

    Enzyme and pathway databases

    BioCyci ADEH290397:GI2Z-1562-MONOMER.

    Family and domain databases

    Gene3Di 3.30.70.580. 1 hit.
    3.30.70.660. 1 hit.
    HAMAPi MF_00171. TruA.
    InterProi IPR020103. PsdUridine_synth_cat_dom.
    IPR001406. PsdUridine_synth_TruA.
    IPR020097. PsdUridine_synth_TruA_a/b_dom.
    IPR020095. PsdUridine_synth_TruA_C.
    IPR020094. PsdUridine_synth_TruA_N.
    [Graphical view ]
    PANTHERi PTHR11142. PTHR11142. 1 hit.
    Pfami PF01416. PseudoU_synth_1. 2 hits.
    [Graphical view ]
    PIRSFi PIRSF001430. tRNA_psdUrid_synth. 1 hit.
    SUPFAMi SSF55120. SSF55120. 1 hit.
    TIGRFAMsi TIGR00071. hisT_truA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 2CP-CImported.

    Entry informationi

    Entry nameiQ2II39_ANADE
    AccessioniPrimary (citable) accession number: Q2II39
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 7, 2006
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3