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Q2II39 (Q2II39_ANADE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
tRNA pseudouridine synthase A HAMAP-Rule MF_00171

EC=5.4.99.12 HAMAP-Rule MF_00171
Alternative name(s):
tRNA pseudouridine(38-40) synthase HAMAP-Rule MF_00171
tRNA pseudouridylate synthase I HAMAP-Rule MF_00171
tRNA-uridine isomerase I HAMAP-Rule MF_00171
Gene names
Name:truA HAMAP-Rule MF_00171
Ordered Locus Names:Adeh_1544 EMBL ABC81317.1
OrganismAnaeromyxobacter dehalogenans (strain 2CP-C) [Complete proteome] [HAMAP] EMBL ABC81317.1
Taxonomic identifier290397 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeAnaeromyxobacter

Protein attributes

Sequence length272 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs By similarity. HAMAP-Rule MF_00171 SAAS SAAS020097

Catalytic activity

tRNA uridine(38-40) = tRNA pseudouridine(38-40). HAMAP-Rule MF_00171 RuleBase RU003792 SAAS SAAS020097

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00171

Sequence similarities

Belongs to the tRNA pseudouridine synthase TruA family. HAMAP-Rule MF_00171 RuleBase RU003792

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site531Nucleophile By similarity HAMAP-Rule MF_00171 PIRSR PIRSR001430-1
Binding site1111Substrate By similarity HAMAP-Rule MF_00171 PIRSR PIRSR001430-2

Sequences

Sequence LengthMass (Da)Tools
Q2II39 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: 3F9044D34321EA21

FASTA27228,851
        10         20         30         40         50         60 
MERRSYALRL AYDGGRFRGF QRQPGLPTVQ QALEEALERL GVRAQLHVAA RTDAGVHALA 

        70         80         90        100        110        120 
QVVSFSARAA LDPAALRRGL NEGLPEGILV LDAARVGPSF HARGSAASRT YVYLVGAPPP 

       130        140        150        160        170        180 
EGLRPYAWTL PDARAFPELA EVPPLDAAAM REALGAAVGE HDFVGFARPG EQRGTVRTLL 

       190        200        210        220        230        240 
RAEVVEAGWA PLVAVVLEGK GFLRAMVRNL VGTAVAVGLG RAPPDVIRTL LATRGRYRGV 

       250        260        270 
RAPGWGLTLA AVRYPDGAWP SPAAPPDPAA SR 

« Hide

References

[1]"Complete sequence of Anaeromyxobacter dehalogenans 2CP-C."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. expand/collapse author list , Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S., Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 2CP-C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000251 Genomic DNA. Translation: ABC81317.1.
RefSeqYP_464754.1. NC_007760.1.

3D structure databases

ProteinModelPortalQ2II39.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290397.Adeh_1544.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABC81317; ABC81317; Adeh_1544.
GeneID3888071.
KEGGade:Adeh_1544.
PATRIC20919211. VBIAnaDeh31384_1594.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0101.
HOGENOMHOG000248674.
KOK06173.
OMAPDARAFP.
OrthoDBEOG6Z9B4R.

Enzyme and pathway databases

BioCycADEH290397:GI2Z-1562-MONOMER.

Family and domain databases

Gene3D3.30.70.580. 1 hit.
3.30.70.660. 1 hit.
HAMAPMF_00171. TruA.
InterProIPR020103. PsdUridine_synth_cat_dom.
IPR001406. PsdUridine_synth_TruA.
IPR020097. PsdUridine_synth_TruA_a/b_dom.
IPR020095. PsdUridine_synth_TruA_C.
IPR020094. PsdUridine_synth_TruA_N.
[Graphical view]
PANTHERPTHR11142. PTHR11142. 1 hit.
PfamPF01416. PseudoU_synth_1. 2 hits.
[Graphical view]
PIRSFPIRSF001430. tRNA_psdUrid_synth. 1 hit.
SUPFAMSSF55120. SSF55120. 1 hit.
TIGRFAMsTIGR00071. hisT_truA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ2II39_ANADE
AccessionPrimary (citable) accession number: Q2II39
Entry history
Integrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: June 11, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)