ID   ARLY_ANADE              Reviewed;         467 AA.
AC   Q2IGX8;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   16-JUN-2009, entry version 28.
DE   RecName: Full=Argininosuccinate lyase;
DE            Short=ASAL;
DE            EC=4.3.2.1;
DE   AltName: Full=Arginosuccinase;
GN   Name=argH; OrderedLocusNames=Adeh_4071;
OS   Anaeromyxobacter dehalogenans (strain 2CP-C).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Myxococcaceae; Anaeromyxobacter.
OX   NCBI_TaxID=290397;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C.,
RA   Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S.,
RA   Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: 2-(N(omega)-L-arginino)succinate = fumarate +
CC       L-arginine.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; L-
CC       arginine from L-ornithine and carbamoyl phosphate: step 3/3.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the lyase 1 family. Argininosuccinate lyase
CC       subfamily.
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DR   EMBL; CP000251; ABC83835.1; -; Genomic_DNA.
DR   RefSeq; YP_467272.1; -.
DR   GeneID; 3888262; -.
DR   GenomeReviews; CP000251_GR; Adeh_4071.
DR   KEGG; ade:Adeh_4071; -.
DR   HOGENOM; Q2IGX8; -.
DR   OMA; Q2IGX8; MAEDLIF.
DR   BioCyc; ADEH290397:ADEH_4071-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004056; F:argininosuccinate lyase activity; IEA:HAMAP.
DR   GO; GO:0042450; P:arginine biosynthetic process via ornithine; IEA:InterPro.
DR   HAMAP; MF_00006; -; 1.
DR   InterPro; IPR009049; Argininosuccinate_lyase.
DR   InterPro; IPR003031; D_crystallin.
DR   InterPro; IPR000362; Fumarate_lyase.
DR   PANTHER; PTHR11444:SF3; argH; 1.
DR   Pfam; PF00206; Lyase_1; 1.
DR   PRINTS; PR00145; DCRYSTALLIN.
DR   PRINTS; PR00149; FUMRATELYASE.
DR   TIGRFAMs; TIGR00838; argH; 1.
DR   PROSITE; PS00163; FUMARATE_LYASES; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Arginine biosynthesis; Complete proteome;
KW   Cytoplasm; Lyase.
FT   CHAIN         1    467       Argininosuccinate lyase.
FT                                /FTId=PRO_0000240710.
SQ   SEQUENCE   467 AA;  50416 MW;  A6707CE7C612F6C0 CRC64;
     MRANSKAKPV SRAALAGEAD PRLVALSVSI QDDGALYAED IRGSQAHVSM LAAQGIVPKA
     AARRIVAALD QVRAEFAAGR IRFDPALEDV HTHVERRLGE LVGKDAGYLH AGRSRNDQVA
     LDERLFIVGA CDRCDAALER LQRAFLGQAR AHERTILPGY THLQRAQPVS LAHHLLAYVE
     MFGRDRERFA EVRRRAAVSP LGSGALAGTT LPLDREAVAA RLGLAGVTHN SLDAVSDRDS
     AAELLFACAL AAVHLSRIGE ELVLWTTKEF GFATLSDAFA TGSSLMPQKK NPDVGELARG
     RAGRALGDLV ALLAILKGLP LSYNRDLQED KRPLLGGPEA LVLTADAVAG AVGTATFHAE
     RMEEALGSGE ALATDAAEYL VERGVPFREA HEAVGKAAAF SAREGRPMAR LTAAEWASFH
     RRFEKDVLRC FDARRSLKRR ELPGAPGPRA VRAELRRWEK ALGKARR
//