ID   TRMB_ANADE              Reviewed;         201 AA.
AC   Q2IG43;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   05-MAY-2009, entry version 21.
DE   RecName: Full=tRNA (guanine-N(7)-)-methyltransferase;
DE            EC=2.1.1.33;
DE   AltName: Full=tRNA(m7G46)-methyltransferase;
GN   Name=trmB; OrderedLocusNames=Adeh_3785;
OS   Anaeromyxobacter dehalogenans (strain 2CP-C).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Myxococcaceae; Anaeromyxobacter.
OX   NCBI_TaxID=290397;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C.,
RA   Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S.,
RA   Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the formation of N(7)-methylguanine at
CC       position 46 (m7G46) in tRNA (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-
CC       homocysteine + tRNA containing N(7)-methylguanine.
CC   -!- PATHWAY: tRNA modification; N(7)-methylguanine-tRNA biosynthesis.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. TrmB
CC       family.
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DR   EMBL; CP000251; ABC83551.1; -; Genomic_DNA.
DR   RefSeq; YP_466988.1; -.
DR   GeneID; 3888282; -.
DR   GenomeReviews; CP000251_GR; Adeh_3785.
DR   KEGG; ade:Adeh_3785; -.
DR   HOGENOM; Q2IG43; -.
DR   OMA; Q2IG43; PDPWWKR.
DR   BioCyc; ADEH290397:ADEH_3785-MON; -.
DR   GO; GO:0008176; F:tRNA (guanine-N7-)-methyltransferase activity; IEA:HAMAP.
DR   GO; GO:0006400; P:tRNA modification; IEA:HAMAP.
DR   HAMAP; MF_01057; -; 1.
DR   InterPro; IPR003358; tRNA_(Gua-N-7)_MeTrfase.
DR   PANTHER; PTHR23417:SF1; Methyltransf_4; 1.
DR   Pfam; PF02390; Methyltransf_4; 1.
DR   TIGRFAMs; TIGR00091; CHP91; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Methyltransferase; S-adenosyl-L-methionine;
KW   Transferase; tRNA processing.
FT   CHAIN         1    201       tRNA (guanine-N(7)-)-methyltransferase.
FT                                /FTId=PRO_0000288117.
FT   BINDING      33     33       S-adenosyl-L-methionine (By similarity).
FT   BINDING      58     58       S-adenosyl-L-methionine (By similarity).
FT   BINDING      85     85       S-adenosyl-L-methionine (By similarity).
FT   BINDING     108    108       S-adenosyl-L-methionine (By similarity).
FT   BINDING     112    112       Substrate (By similarity).
FT   BINDING     144    144       Substrate (Potential).
SQ   SEQUENCE   201 AA;  22375 MW;  3A642EC0FF43E3C5 CRC64;
     MIFSIEDDAP IVRDLLPDWR ARFGEAGGRL ELEIGCGHGG FALGFARAFP ERALVGIEQR
     RKFAAELAAK GARHGLSNLL VLNGDARLLA PRLFAAGSLA AIHVHFPDPW WKRRHHRRRL
     VDDRMSALLL GLLAPGGVLD FRTDVERYAR EAVVRLEEVG FRNAAGPGRF AEAAPDEIPS
     TRERRYLASG EPVWRLRLVK A
//