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Q2IG43

- TRMB_ANADE

UniProt

Q2IG43 - TRMB_ANADE

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Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene
trmB, Adeh_3785
Organism
Anaeromyxobacter dehalogenans (strain 2CP-C)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei33 – 331S-adenosyl-L-methionine By similarity
Binding sitei58 – 581S-adenosyl-L-methionine By similarity
Binding sitei85 – 851S-adenosyl-L-methionine By similarity
Active sitei108 – 1081 By similarity
Binding sitei108 – 1081S-adenosyl-L-methionine By similarity
Binding sitei112 – 1121Substrate By similarity
Binding sitei144 – 1441Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciADEH290397:GI2Z-3840-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:Adeh_3785
OrganismiAnaeromyxobacter dehalogenans (strain 2CP-C)
Taxonomic identifieri290397 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeAnaeromyxobacter
ProteomesiUP000001935: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 201201tRNA (guanine-N(7)-)-methyltransferaseUniRule annotationPRO_0000288117Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290397.Adeh_3785.

Structurei

3D structure databases

ProteinModelPortaliQ2IG43.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000003597.
KOiK03439.
OMAiGFEVENS.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2IG43-1 [UniParc]FASTAAdd to Basket

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MIFSIEDDAP IVRDLLPDWR ARFGEAGGRL ELEIGCGHGG FALGFARAFP    50
ERALVGIEQR RKFAAELAAK GARHGLSNLL VLNGDARLLA PRLFAAGSLA 100
AIHVHFPDPW WKRRHHRRRL VDDRMSALLL GLLAPGGVLD FRTDVERYAR 150
EAVVRLEEVG FRNAAGPGRF AEAAPDEIPS TRERRYLASG EPVWRLRLVK 200
A 201
Length:201
Mass (Da):22,375
Last modified:March 7, 2006 - v1
Checksum:i3A642EC0FF43E3C5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000251 Genomic DNA. Translation: ABC83551.1.
RefSeqiWP_011422833.1. NC_007760.1.
YP_466988.1. NC_007760.1.

Genome annotation databases

EnsemblBacteriaiABC83551; ABC83551; Adeh_3785.
GeneIDi3888282.
KEGGiade:Adeh_3785.
PATRICi20923819. VBIAnaDeh31384_3866.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000251 Genomic DNA. Translation: ABC83551.1 .
RefSeqi WP_011422833.1. NC_007760.1.
YP_466988.1. NC_007760.1.

3D structure databases

ProteinModelPortali Q2IG43.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290397.Adeh_3785.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABC83551 ; ABC83551 ; Adeh_3785 .
GeneIDi 3888282.
KEGGi ade:Adeh_3785.
PATRICi 20923819. VBIAnaDeh31384_3866.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000003597.
KOi K03439.
OMAi GFEVENS.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci ADEH290397:GI2Z-3840-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2CP-C.

Entry informationi

Entry nameiTRMB_ANADE
AccessioniPrimary (citable) accession number: Q2IG43
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: March 7, 2006
Last modified: September 3, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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