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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Anaeromyxobacter dehalogenans (strain 2CP-C)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei138GTPUniRule annotation1
Binding sitei142GTPUniRule annotation1
Binding sitei186GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi20 – 24GTPUniRule annotation5
Nucleotide bindingi107 – 109GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciADEH290397:G1G5W-3918-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Adeh_3778Imported
OrganismiAnaeromyxobacter dehalogenans (strain 2CP-C)Imported
Taxonomic identifieri290397 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeAnaeromyxobacteraceaeAnaeromyxobacter
Proteomesi

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi290397.Adeh_3778

Structurei

3D structure databases

ProteinModelPortaliQ2IG37
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 204TubulinInterPro annotationAdd BLAST193
Domaini206 – 324Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q2IG37-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEYTDRQDA AKIKVIGVGG GGGNAINTMV AGRLEGVEFI AANTDVQALA
60 70 80 90 100
ANKAGVKIQL GKSASRGLGA GANPEVGRTA ALEEREQIAA ALEGADMVFV
110 120 130 140 150
TAGMGGGTGT GGAPVVADIA KATGALTVGV VTKPFLFEGN KRRKQAEAGI
160 170 180 190 200
AELAAAVDTL IVIPNQRLLS VAGENMSLAD AFKRADEVLL NAVQGISDLI
210 220 230 240 250
TVHGIVNVDF ADVRTIMGGQ GMALMGTGRS SGEQRTMEAM QAAISSPLLE
260 270 280 290 300
DVTLDGATGL LVNITGGPNL TLHEVNEAVS MAQAAADSDA NIIFGSVIDE
310 320 330 340 350
RLGDEVKITV IATGFQAREE RSRAIARKVE PVEARAPATV RQVPPPLPVE
360 370 380 390 400
AAAKPPIRLQ TPAAPAHVTA PAKVSFRREA PVYRPADEDQ YDIPAFLRRG

NPPRE
Length:405
Mass (Da):41,931
Last modified:March 7, 2006 - v1
Checksum:iEB8AAEA0B7307154
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000251 Genomic DNA Translation: ABC83544.1
RefSeqiWP_011422826.1, NC_007760.1

Genome annotation databases

EnsemblBacteriaiABC83544; ABC83544; Adeh_3778
KEGGiade:Adeh_3778

Entry informationi

Entry nameiQ2IG37_ANADE
AccessioniPrimary (citable) accession number: Q2IG37
Entry historyiIntegrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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