ID   NTPA_ANADE              Reviewed;         235 AA.
AC   Q2IEX2;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   16-JUN-2009, entry version 22.
DE   RecName: Full=Nucleoside-triphosphatase;
DE            EC=3.6.1.15;
DE   AltName: Full=Nucleoside triphosphate phosphohydrolase;
DE            Short=NTPase;
GN   OrderedLocusNames=Adeh_3360;
OS   Anaeromyxobacter dehalogenans (strain 2CP-C).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Myxococcaceae; Anaeromyxobacter.
OX   NCBI_TaxID=290397;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C.,
RA   Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S.,
RA   Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and
CC       dITP/ITP. Might exclude non-standard purines from DNA precursor
CC       pool, preventing thus incorporation into DNA and avoiding
CC       chromosomal lesions (By similarity).
CC   -!- CATALYTIC ACTIVITY: NTP + H(2)O = NDP + phosphate.
CC   -!- COFACTOR: Divalent cations (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the HAM1 NTPase family.
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DR   EMBL; CP000251; ABC83127.1; -; Genomic_DNA.
DR   RefSeq; YP_466564.1; -.
DR   GeneID; 3889350; -.
DR   GenomeReviews; CP000251_GR; Adeh_3360.
DR   KEGG; ade:Adeh_3360; -.
DR   HOGENOM; Q2IEX2; -.
DR   OMA; Q2IEX2; NACLKAS.
DR   BioCyc; ADEH290397:ADEH_3360-MON; -.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:HAMAP.
DR   HAMAP; MF_01405; -; 1.
DR   InterPro; IPR002637; Ham1p-like.
DR   PANTHER; PTHR11067; Ham1p_like; 1.
DR   Pfam; PF01725; Ham1p_like; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase.
FT   CHAIN         1    235       Nucleoside-triphosphatase.
FT                                /FTId=PRO_1000068407.
SQ   SEQUENCE   235 AA;  24465 MW;  BDF0A6FB224A2B89 CRC64;
     MDLLFGSTNP GKLRELRRLV AGLPLRVVSP DDLGRPLPVV VEDGATFQAN AEKKAVAWAR
     WSGLHAVADD SGLCVDALGG APGVHSARWS DLEPEGPASP VCELAGVAEL ELGPVAGRAA
     RDERNNDKLL AALSGLPDPR RGARYEAVLA LARPDGTLVG TVTGTCPGRI GHARRGDGGF
     GYDPLFVPAA ELAAGEGARV RTMAELSSDE KDALSHRGEA FRKLLPMLAA LARGA
//