ID   G6PI_ANADE              Reviewed;         550 AA.
AC   Q2IE39;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=Glucose-6-phosphate isomerase;
DE            Short=GPI;
DE            EC=5.3.1.9;
DE   AltName: Full=Phosphoglucose isomerase;
DE            Short=PGI;
DE   AltName: Full=Phosphohexose isomerase;
DE            Short=PHI;
GN   Name=pgi; OrderedLocusNames=Adeh_3080;
OS   Anaeromyxobacter dehalogenans (strain 2CP-C).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Myxococcaceae; Anaeromyxobacter.
OX   NCBI_TaxID=290397;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C.,
RA   Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S.,
RA   Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: D-glucose 6-phosphate = D-fructose 6-
CC       phosphate.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 2/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the GPI family.
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DR   EMBL; CP000251; ABC82849.1; -; Genomic_DNA.
DR   RefSeq; YP_466286.1; -.
DR   GeneID; 3889158; -.
DR   GenomeReviews; CP000251_GR; Adeh_3080.
DR   KEGG; ade:Adeh_3080; -.
DR   HOGENOM; Q2IE39; -.
DR   OMA; Q2IE39; PYSNDLA.
DR   BioCyc; ADEH290397:ADEH_3080-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:HAMAP.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:HAMAP.
DR   GO; GO:0006096; P:glycolysis; IEA:HAMAP.
DR   HAMAP; MF_00473; -; 1.
DR   InterPro; IPR001672; G6P_Isomerase.
DR   InterPro; IPR018189; Phosphoglucose_isomerase_CS.
DR   PANTHER; PTHR11469; G6P_Isomerase; 1.
DR   Pfam; PF00342; PGI; 1.
DR   PRINTS; PR00662; G6PISOMERASE.
DR   PROSITE; PS00765; P_GLUCOSE_ISOMERASE_1; 1.
DR   PROSITE; PS00174; P_GLUCOSE_ISOMERASE_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Gluconeogenesis; Glycolysis; Isomerase.
FT   CHAIN         1    550       Glucose-6-phosphate isomerase.
FT                                /FTId=PRO_0000252607.
FT   ACT_SITE    357    357       Proton donor (By similarity).
FT   ACT_SITE    389    389       By similarity.
FT   ACT_SITE    509    509       By similarity.
SQ   SEQUENCE   550 AA;  59816 MW;  03D0A07868C37B35 CRC64;
     MADRNDPLLR TPAWRALETH LAEVRPLHLR ELFARDPGRG DRLAAEGAGL YLDYSKQRVT
     EETVRLLVAL AEARGLPGRR AAMFRGEKVN ATEGRAALHV ALRAPRGERI EVDGKDVVPE
     VHAVLDRMAA FAEQVRSGAW TGFTGRRIRT VVNVGIGGSD LGPAMAYRAL RAYTTREIAF
     RFVSNVDGTD LAEAVRDLDP AETLFLVASK TFTTLETMTN AASARAWLLA ALGDERAVAR
     HFVAISTNEA EVRRFGIDPA NMFGFWDWVG GRYSMDSAIG LSTMIAVGPG GFRELLAGFR
     AMDEHFRDAP LERNLPALVG LIGVWNASLL GAETVAVLPY DQYLDRFPAY LQQLTMESNG
     KRVTASGAPV EGHGTGAIYW GEPGTNGQHS FYQLLHQGTH LVACDFIGFC RTLNPLGRHH
     DLLMANLFAQ GEALAFGKTA EEARAEGTPE ALVPHRTFPG NRPSSTILAD RLGPGTLGAL
     VALYEHAVFT QGVIWDVDSF DQWGVELGKV LANRIVKELE APADPALAHD GSTNALIRRY
     RARRGGSASS
//