Unreviewed, UniProtKB/TrEMBL Q2I7G4 (Q2I7G4_HUMAN)

Names and origin

Protein names

Submitted name:
    ADAM metallopeptidase with thrombospondin type 1 motif 17 EMBL ABB70740.1

Gene names

Name:

ADAMTS17 EMBL ABB70740.1

Organism

Homo sapiens (Human) EMBL ABB70740.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1095 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 peptidase M12B domain. RuleBase RU004141V0 Spearmint SPM001590

Ontologies

Keywords
PTM	Disulfide bond Spearmint SPM002870
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro proteinaceous extracellular matrix Inferred from electronic annotation. Source: InterPro
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2I7G4-1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: A5D66E0793554D5D	FASTA	1,095	121,072
	10 20 30 40 50 60 MCDGALLPPL VLPVLLLLVW GLDPGTAVGD AAADVEVVLP WRVRPDDVHL PPLPAAPGPR 70 80 90 100 110 120 RRRRPRTPPA APRARPGERA LLLHLPAFGR DLYLQLRRDL RFLSRGFEVE EAGAARRRGR 130 140 150 160 170 180 PAELCFYSGR VLGHPGSLVS LSACGAAGGL VGLIQLGQEQ VLIQPLNNSQ GPFSGREHLI 190 200 210 220 230 240 RRKWSLTPSP SAEAQRPEQL CKVLTEKKKP TWGRPSRDWR ERRNAIRLTS EHTVETLVVA 250 260 270 280 290 300 DADMVQYHGA EAAQRFILTV MNMVYNMFQH QSLGIKINIQ VTKLVLLRQR PAKLSIGHHG 310 320 330 340 350 360 ERSLESFCHW QNEEYGGARY LGNNQVPGGK DDPPLVDAAV FVTRTDFCVH KDEPCDTVGI 370 380 390 400 410 420 AYLGGVCSAK RKCVLAEDNG LNLAFTIAHE LGHNLGMNHD DDHSSCAGRS HIMSGEWVKG 430 440 450 460 470 480 RNPSDLSWSS CSRDDLENFL KSKVSTCLLV TDPRSQHTVR LPHKLPGMHY SANEQCQILF 490 500 510 520 530 540 GMNATFCRNM EHLMCAGLWC LVEGDTSCKT KLDPPLDGTE CGADKWCRAG ECVSKTPIPE 550 560 570 580 590 600 HVDGDWSPWG AWSMCSRTCG TGARFTQRKC DNPPPGPGGT HCPGASVEHA VCENLPCPKG 610 620 630 640 650 660 LPSFRDQQCQ AHDRLSPKKK GLLTAVVVDD KPCELYCSPL GKESPLLVAD RVLDGTPCGP 670 680 690 700 710 720 YETDLCVHGK CQKIGCDGII GSAAKEDRCG VCSGDGKTCH LVKGDFSHAR GTALKDSGKG 730 740 750 760 770 780 SINSDWKIEL PGEFQIAGTT VRYVRRGLWE KISAKGPTKL PLHLMVLLFH DQDYGIHYEY 790 800 810 820 830 840 TVPVNRTAEN QSEPEKPQDS LFIWTHSGWE GCSVQCGGGE RRTIVSCTRI VNKTTTLVND 850 860 870 880 890 900 SDCPQASRPE PQVRRCNLHP CQSRWVAGPW SPCSATCEKG FQHREVTCVY QLQNGTHVAT 910 920 930 940 950 960 RPLYCPGPRP AAVQSCEGQD CLSIWEASEW SQCSASCGKG VWKRTVACTN SQGKCDASTR 970 980 990 1000 1010 1020 PRAEEACEDY SGCYEWKTGD WSTCSSTCGK GLQSRVVQCM HKVTGRHGSE CPALSKPAPY 1030 1040 1050 1060 1070 1080 RQCYQEVCND RINANTITSP RLAALTYKCT RDQWTVYCRV IREKNLCQDM RWYQRCCQTC 1090 RDFYANKMRQ PPPNS

References

[1]	"Genetic variation in ADAMTS17 gene." Tan J., Davila S., Hibberd M.L., Seielstad M. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ217943 Genomic DNA. Translation: ABB70740.1.
IPI	IPI00152635.
UniGene	Hs.513200
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000140470. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:17109. ADAMTS17.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q2I7G4.
Gene expression databases
ArrayExpress	Q2I7G4.
Bgee	Q2I7G4.
Family and domain databases
InterPro	IPR010294. ADAM_spacer1. IPR001590. Peptidase_M12B. IPR013273. Peptidase_M12B_ADAM-TS. IPR002870. Peptidase_M12B_N. IPR010909. PLAC. IPR000884. Thrombospondin_1_rpt. IPR007087. Znf_C2H2. [Graphical view]
Pfam	PF05986. ADAM_spacer1. 1 hit. PF01562. Pep_M12B_propep. 1 hit. PF08686. PLAC. 1 hit. PF01421. Reprolysin. 1 hit. PF00090. TSP_1. 4 hits. [Graphical view]
PRINTS	PR01857. ADAMTSFAMILY.
SMART	SM00209. TSP1. 5 hits. [Graphical view]
PROSITE	PS50215. ADAM_MEPRO. 1 hit. PS50900. PLAC. 1 hit. PS50092. TSP1. 5 hits. PS00028. ZINC_FINGER_C2H2_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2I7G4_HUMAN

Accession

Primary (citable) accession number: Q2I7G4

Entry history

Integrated into UniProtKB/TrEMBL:	March 7, 2006
Last sequence update:	March 7, 2006
Last modified:	May 5, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)