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Q2HZD7

- Q2HZD7_CHICK

UniProt

Q2HZD7 - Q2HZD7_CHICK

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Protein
Submitted name: Receptor tyrosine-protein kinase
Gene
erbB3
Organism
Gallus gallus (Chicken)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.SAAS annotations

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. receptor signaling protein tyrosine kinase activity Source: InterPro
  3. transmembrane receptor protein tyrosine kinase activity Source: InterPro

GO - Biological processi

  1. transmembrane receptor protein tyrosine kinase signaling pathway Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, ReceptorImported, Transferase, Tyrosine-protein kinaseSAAS annotations

Keywords - Ligandi

ATP-bindingSAAS annotations, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Receptor tyrosine-protein kinaseImported
Gene namesi
Name:erbB3Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

PhosphoproteinSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliQ2HZD7.
SMRiQ2HZD7. Positions 29-632, 688-980.

Family & Domainsi

Sequence similaritiesi

Contains protein kinase domain.SAAS annotations

Phylogenomic databases

HOVERGENiHBG000490.
KOiK05084.
PhylomeDBiQ2HZD7.

Family and domain databases

Gene3Di3.80.20.20. 2 hits.
InterProiIPR000494. EGF_rcpt_L.
IPR006211. Furin-like_Cys-rich_dom.
IPR006212. Furin_repeat.
IPR009030. Growth_fac_rcpt_N_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR020635. Tyr_kinase_cat_dom.
IPR016245. Tyr_kinase_EGF/ERB/XmrK_rcpt.
[Graphical view]
PfamiPF00757. Furin-like. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
PF01030. Recep_L_domain. 2 hits.
[Graphical view]
PIRSFiPIRSF000619. TyrPK_EGF-R. 1 hit.
PRINTSiPR00109. TYRKINASE.
SMARTiSM00261. FU. 5 hits.
SM00219. TyrKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
SSF57184. SSF57184. 2 hits.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2HZD7-1 [UniParc]FASTAAdd to Basket

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MPRSRFRPRA LLCAVLLLLL HSPAPGSGQA VCAGTLNGLS VTGDAQHQYR     50
TLHKMYNNCE IVMGNLEIVL IDHTQDLSFL QTIREVTGYI LIAMNVFSTL 100
PLRNLRVIRG TQFYEEKYAL FVLLNYNPNA THALRQLGLN RLTEILAGGV 150
YIEKNEQLCH VDTVEWRDIM RDPRLEPVVG DNGRACAPCH ESCGGHCWGP 200
GPEDCQQLTK TICAPQCNGR CFGRAPNECC HEECAGGCTG PLQTHCFACR 250
HFNDSGACVP LCPQPLIYNK LTFQLEPNPD TKYQYGSVCV RSCPHNFVVD 300
QSSCVRACPS NKMEVEKNGL KMCEPCAGLC PKACEGTGAG SHYQTVDSSN 350
IDSFVNCTKI LGNLDFLITG LEGDPWRNIS ALDPEKLNVF RTVREITGYL 400
NIQSWPKHMH NFSVFSNLET IGGRSLYNRG FSLLIMKNDN VTSLGLRSLR 450
EVSAGRVYIT ENRRLCYLHT VQWAALSRRR ADLDIRNNKP RGKCQQEGKV 500
CDPLCSADGC WGPGPAQCLS CRHYSRRGVC VESCSFTQGE TREFAEGTEC 550
FECHPECERV EGGITCNGSG ADTCTRCAHY RDGPHCVERC PEGILGERGP 600
IYKYPDSSRE CRPCHENCTR GCTGPLLQDC LGDALPSARR APTVIAVLVV 650
GGLFLSCSCV LLSLLYWRGK KIQKKRAMRR YLERGESLEP LDPSEKANKV 700
LARIFKETEL KRLKVLGSGV FGTVHKGIWI PDGDSIKIPV SIKVIQDWSG 750
QQSFHAVTDH MLAIGSLDHA YIVRLLGICP GPQLQLVTQL LPLGSLLDYV 800
RKNRGSISPQ LLLNWCVQVA KGMYYLEEHR MVHRNLAARN VLLKSPSQAQ 850
VADFGIADLL YPDDKKYFYN EVKTPIKWMA LESIHFGKYT HQSDVWSYGV 900
TLWEMMTFGA EPYAGIRLPE VPDLLEKGER LPQPHICTID VYMVMVKCWM 950
IDENIRPTFK ELANEFTRMA RDPPRYLVIK ESGAVPPAEP PTLSDKELDE 1000
METLELEEEE LDVSFGLCPP RPRGSCTRSP SLLSPPAGYI PMNQPGLGSR 1050
QGTGTRPPRR SRQESVGRTV SESSEGRGTA SELDLAEGLS LSGSLCRSLR 1100
SRGDSAYLSQ RESFPPPPPG SEGSEEDANG YVTPSCAGRE PGPTGGSVPE 1150
LEEEYEYMNR QPGAPLQAPP PRPASLEELG YEYMEVGSEL GSPAGPPQSR 1200
GEEEEDYEYM NKQPRLSRSL GNVVGGLGPR HESCPPRHDG YTDMRPGEPT 1250
PAPPEEQGYE EMEAVLAPRG PPCPGCRSPP GPPPTCMKPL RSLEASDCAF 1300
DNPDYWHSRL FAKVDAQRT 1319
Length:1,319
Mass (Da):146,222
Last modified:March 7, 2006 - v1
Checksum:iD6E487257700A0B2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ358720 mRNA. Translation: ABC88378.1.
RefSeqiNP_001038134.1. NM_001044669.1.
UniGeneiGga.33709.

Genome annotation databases

GeneIDi693245.
KEGGigga:693245.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ358720 mRNA. Translation: ABC88378.1 .
RefSeqi NP_001038134.1. NM_001044669.1.
UniGenei Gga.33709.

3D structure databases

ProteinModelPortali Q2HZD7.
SMRi Q2HZD7. Positions 29-632, 688-980.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 693245.
KEGGi gga:693245.

Organism-specific databases

CTDi 2065.

Phylogenomic databases

HOVERGENi HBG000490.
KOi K05084.
PhylomeDBi Q2HZD7.

Miscellaneous databases

NextBioi 20902513.
PROi Q2HZD7.

Family and domain databases

Gene3Di 3.80.20.20. 2 hits.
InterProi IPR000494. EGF_rcpt_L.
IPR006211. Furin-like_Cys-rich_dom.
IPR006212. Furin_repeat.
IPR009030. Growth_fac_rcpt_N_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR020635. Tyr_kinase_cat_dom.
IPR016245. Tyr_kinase_EGF/ERB/XmrK_rcpt.
[Graphical view ]
Pfami PF00757. Furin-like. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
PF01030. Recep_L_domain. 2 hits.
[Graphical view ]
PIRSFi PIRSF000619. TyrPK_EGF-R. 1 hit.
PRINTSi PR00109. TYRKINASE.
SMARTi SM00261. FU. 5 hits.
SM00219. TyrKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
SSF57184. SSF57184. 2 hits.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning of Chicken erbB-3 and Characterization of its Expression in the Chicken Ovary."
    Wang Y., Li J., Leung F.C.
    Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ2HZD7_CHICK
AccessioniPrimary (citable) accession number: Q2HZD7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: July 9, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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