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Protein

Respiratory burst oxidase homolog protein C

Gene

RBOHC

Organism
Solanum tuberosum (Potato)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Calcium-dependent NADPH oxidase that generates superoxide. May be responsible for the oxidative burst in response to pathogen attack in the leaves.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi258CalciumBy similarity1
Metal bindingi260CalciumBy similarity1
Metal bindingi262CalciumBy similarity1
Metal bindingi264Calcium; via carbonyl oxygenBy similarity1
Metal bindingi269CalciumBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi258 – 269PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase, Peroxidase
LigandCalcium, FAD, Flavoprotein, Metal-binding, NADP

Protein family/group databases

PeroxiBasei4547. StRboh03.

Names & Taxonomyi

Protein namesi
Recommended name:
Respiratory burst oxidase homolog protein C (EC:1.11.1.-, EC:1.6.3.-)
Alternative name(s):
NADPH oxidase RBOHC
StRBOHC
Gene namesi
Name:RBOHC
OrganismiSolanum tuberosum (Potato)
Taxonomic identifieri4113 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
Proteomesi
  • UP000011115 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 369CytoplasmicSequence analysisAdd BLAST369
Transmembranei370 – 390HelicalSequence analysisAdd BLAST21
Topological domaini391 – 402ExtracellularSequence analysisAdd BLAST12
Transmembranei403 – 423HelicalSequence analysisAdd BLAST21
Topological domaini424 – 454CytoplasmicSequence analysisAdd BLAST31
Transmembranei455 – 475HelicalSequence analysisAdd BLAST21
Topological domaini476 – 509ExtracellularSequence analysisAdd BLAST34
Transmembranei510 – 530HelicalSequence analysisAdd BLAST21
Topological domaini531 – 545CytoplasmicSequence analysisAdd BLAST15
Transmembranei546 – 566HelicalSequence analysisAdd BLAST21
Topological domaini567 – 580ExtracellularSequence analysisAdd BLAST14
Transmembranei581 – 599HelicalSequence analysisAdd BLAST19
Topological domaini600 – 732CytoplasmicSequence analysisAdd BLAST133
Transmembranei733 – 753HelicalSequence analysisAdd BLAST21
Topological domaini754 – 938ExtracellularSequence analysisAdd BLAST185

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003137651 – 938Respiratory burst oxidase homolog protein CAdd BLAST938

Post-translational modificationi

Phosphorylated by CPK.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ2HXL0.

Expressioni

Tissue specificityi

Expressed in leaves.1 Publication

Interactioni

Subunit structurei

Monomer and homodimer.By similarity

Protein-protein interaction databases

STRINGi4113.PGSC0003DMT400036734.

Structurei

3D structure databases

ProteinModelPortaliQ2HXL0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini245 – 280EF-hand 1PROSITE-ProRule annotationAdd BLAST36
Domaini289 – 324EF-hand 2PROSITE-ProRule annotationAdd BLAST36
Domaini408 – 565Ferric oxidoreductaseAdd BLAST158
Domaini599 – 727FAD-binding FR-typePROSITE-ProRule annotationAdd BLAST129

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni185 – 195EF-hand-like 1By similarityAdd BLAST11
Regioni222 – 233EF-hand-like 2By similarityAdd BLAST12

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili115 – 141Sequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi7 – 15His-rich9

Sequence similaritiesi

Keywords - Domaini

Coiled coil, Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0039. Eukaryota.
ENOG410XNZY. LUCA.
InParanoidiQ2HXL0.
KOiK13447.

Family and domain databases

CDDicd00051. EFh. 1 hit.
InterProiView protein in InterPro
IPR000778. Cyt_b245_heavy_chain.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR013112. FAD-bd_8.
IPR017927. Fd_Rdtase_FAD-bd.
IPR013130. Fe3_Rdtase_TM_dom.
IPR013121. Fe_red_NAD-bd_6.
IPR013623. NADPH_Ox.
IPR017938. Riboflavin_synthase-like_b-brl.
PfamiView protein in Pfam
PF08022. FAD_binding_8. 1 hit.
PF01794. Ferric_reduct. 1 hit.
PF08030. NAD_binding_6. 1 hit.
PF08414. NADPH_Ox. 1 hit.
PRINTSiPR00466. GP91PHOX.
SUPFAMiSSF47473. SSF47473. 1 hit.
SSF63380. SSF63380. 1 hit.
PROSITEiView protein in PROSITE
PS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 2 hits.
PS51384. FAD_FR. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2HXL0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQNSENHHPH HHHHHSDTEI IGNDRASYSG PLSGPLNKRG GKKSARFNIP
60 70 80 90 100
ESTDIGTSAG AGAKSNDDAY VEITLDVRED SVAVHSVKTA GGADVEDPEL
110 120 130 140 150
ALLAKGLEKK STLGASLVRN ASSRIRQVSQ ELKRLASLNK RPIPTGRFDR
160 170 180 190 200
NKSAAAHALK GLKFISKTDG GAGWAAVEKR FDEITAPTTG LLPRAKFGEC
210 220 230 240 250
IGMNKESKEF AGELYDALAR RRNITTDSIN KAQLKEFWDQ VADQSFDTRL
260 270 280 290 300
QTFFDMVDKD ADGRITEEEV REIIGLSASA NRLSTIQKQS DEYAAMIMEE
310 320 330 340 350
LDPNNLGYIM IENLEMLLLQ APNQSVQRGG ESRNLSQMLS QKLKHTQEPN
360 370 380 390 400
PLVRWYKSFM YFLLDNWQRV WVLLLWIGIM AVLFTWKYIQ YKQKAAYDVM
410 420 430 440 450
GPCVCLAKGA AETIKLNMAI ILLPVCRNTI TWLRNKTRLG SAVPFDDNLN
460 470 480 490 500
FHKVIAVAIA LGVAIHGLAH LTCDFPKLLN ASEEAYEPMI YYFGEQPESY
510 520 530 540 550
WWFVRGVEGV TGIIMVVLMA IAFTLATPWF RRGRVSFPKP FHKLTGFNAF
560 570 580 590 600
WYSHHLFIIV YTLLIVHGEK LYITKDWYKR STWMYLTVPL VLYAGERLLR
610 620 630 640 650
AFRSSIKAVK ILKVAVYPGN VLALHMSKPQ GYKYKSGQYM FVNCAAVSPF
660 670 680 690 700
EWHPFSITSA PGDDHLSVHI RTLGDWTRQL KTVFSEVCQP PPNGKSGLLR
710 720 730 740 750
ADYLQGENNP NFPRVLIDGP YGAPAQDYKQ YEVVLLVGLG IGATPMISIV
760 770 780 790 800
KDIVNNMKAM DEEENSLENG NGMSNAAQNA SPNMAQKRGK SSSASGGNSF
810 820 830 840 850
NTRRAYFYWV TREQGSFDWF KGIMNEAAEM DHKGVIEMHN YCTSVYEEGD
860 870 880 890 900
ARSALITMLQ SLHHAKSGVD IVSGTRVKSH FAKPNWRNVY KRIALNHPEA
910 920 930
KVGVFYCGAP ALTKELKQHA LNFSHKTSTK FDFHKENF
Length:938
Mass (Da):105,302
Last modified:June 12, 2007 - v2
Checksum:i9189D640D118A35B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB198716 mRNA. Translation: BAE79344.2.
RefSeqiNP_001275453.1. NM_001288524.1.
UniGeneiStu.19474.

Genome annotation databases

GeneIDi102598898.
KEGGisot:102598898.

Similar proteinsi

Entry informationi

Entry nameiRBOHC_SOLTU
AccessioniPrimary (citable) accession number: Q2HXL0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 12, 2007
Last modified: May 10, 2017
This is version 75 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families