ID   MTA70_MEDTR             Reviewed;         614 AA.
AC   Q2HVD6;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   16-JUN-2009, entry version 16.
DE   RecName: Full=Putative N6-adenosine-methyltransferase MT-A70-like;
DE            EC=2.1.1.62;
GN   ORFNames=MtrDRAFT_AC148918g15v1;
OS   Medicago truncatula (Barrel medic).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   rosids; eurosids I; Fabales; Fabaceae; Papilionoideae; Trifolieae;
OC   Medicago.
OX   NCBI_TaxID=3880;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The International Medicago Genome Annotation Group;
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Putative N6-methyltransferase that methylates adenosine
CC       residues of some mRNAs. N6-methyladenosine (m6A), which is present
CC       at internal sites of some mRNAs, may play a role in the efficiency
CC       of mRNA splicing, transport or translation (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-
CC       adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am.
CC   -!- SUBCELLULAR LOCATION: Nucleus (Probable).
CC   -!- SIMILARITY: Belongs to the MT-A70-like family.
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DR   EMBL; AC148918; ABD28511.1; -; Genomic_DNA.
DR   BRENDA; 2.1.1.62; 266820.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016422; F:mRNA (2'-O-methyladenosine-N6-)-methyltrans...; IEA:EC.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006139; P:nucleobase, nucleoside, nucleotide and nucl...; IEA:InterPro.
DR   InterPro; IPR007757; MT-A70.
DR   Pfam; PF05063; MT-A70; 1.
DR   PROSITE; PS51143; MT_A70; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Nucleus; RNA-binding; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN         1    614       Putative N6-adenosine-methyltransferase
FT                                MT-A70-like.
FT                                /FTId=PRO_0000260071.
FT   COMPBIAS    206    213       Poly-Gln.
FT   COMPBIAS    362    365       Poly-Pro.
SQ   SEQUENCE   614 AA;  69286 MW;  6D23498646697FAA CRC64;
     MEMETDEGIN SLKARIETQH KSHMYMLSSV QSVIPNFVSS LDLSLKVLSS FNHRPFAPTP
     PLTNFNPPKS SSLQQLPQKP SVKTLKTSLV VTTNPVLEKV TPLSVVLSMV AVCLLSRLPF
     MEIDSSTLWR KLENDETFTP QDKAAFQELA GDSGGPTLAV EIALRSMADD NGAVELEEFA
     VSGKSRIMVL NIDRTRLLRQ LPETAQHQLQ QQQDELSLGD GNMNQNQQQI AKCSMNLEDV
     DALINKKSFR EMQKYETAKE LLKIIQTPSI REAAVAAKFK TKGGSQMRPY CDLPTKEDCR
     RRTGSFIACN KLHFRRIIAL HTDINLGDCP FLRTCRHMNT CKYVHYEEDP TPDLPPTMMC
     APPPPLKPLK QQRAEYCSEA ELGQPQWINC DIRNFRMDIL GKFGVIMADP PWDIHMELPY
     GTMADDEMRT LNVPALQTHG LIFLWVTGRA MELGRECLER WGYKCVEEII WVKTNQLQRI
     IRTGRTGHWL NHSKEHCLVG IKGSPEVNRN IDTNVIVSEV RETSRKPDEM YAMMERISPG
     TRKVELFARM HNTHAGWMSL GNQLSGVRLV DEGLRARFKA AYPDVEVQPA SPSRASAMEL
     DSSVAAQTTT SAMM
//