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Q2HVD6 (MTA70_MEDTR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative N6-adenosine-methyltransferase MT-A70-like

EC=2.1.1.62
Gene names
ORF Names:MtrDRAFT_AC148918g15v1
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
Taxonomic identifier3880 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeTrifolieaeMedicago

Protein attributes

Sequence length614 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Putative N6-methyltransferase that methylates adenosine residues of some mRNAs. N6-methyladenosine (m6A), which is present at internal sites of some mRNAs, may play a role in the efficiency of mRNA splicing, transport or translation By similarity.

Catalytic activity

S-adenosyl-L-methionine + m7G(5')pppAm = S-adenosyl-L-homocysteine + m7G(5')pppm6Am.

Subcellular location

Nucleus Probable.

Sequence similarities

Belongs to the MT-A70-like family.

Ontologies

Keywords
   Cellular componentNucleus
   LigandRNA-binding
S-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 614614Putative N6-adenosine-methyltransferase MT-A70-like
PRO_0000260071

Regions

Compositional bias206 – 2138Poly-Gln
Compositional bias362 – 3654Poly-Pro

Sequences

Sequence LengthMass (Da)Tools
Q2HVD6 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: 6D23498646697FAA

FASTA61469,286
        10         20         30         40         50         60 
MEMETDEGIN SLKARIETQH KSHMYMLSSV QSVIPNFVSS LDLSLKVLSS FNHRPFAPTP 

        70         80         90        100        110        120 
PLTNFNPPKS SSLQQLPQKP SVKTLKTSLV VTTNPVLEKV TPLSVVLSMV AVCLLSRLPF 

       130        140        150        160        170        180 
MEIDSSTLWR KLENDETFTP QDKAAFQELA GDSGGPTLAV EIALRSMADD NGAVELEEFA 

       190        200        210        220        230        240 
VSGKSRIMVL NIDRTRLLRQ LPETAQHQLQ QQQDELSLGD GNMNQNQQQI AKCSMNLEDV 

       250        260        270        280        290        300 
DALINKKSFR EMQKYETAKE LLKIIQTPSI REAAVAAKFK TKGGSQMRPY CDLPTKEDCR 

       310        320        330        340        350        360 
RRTGSFIACN KLHFRRIIAL HTDINLGDCP FLRTCRHMNT CKYVHYEEDP TPDLPPTMMC 

       370        380        390        400        410        420 
APPPPLKPLK QQRAEYCSEA ELGQPQWINC DIRNFRMDIL GKFGVIMADP PWDIHMELPY 

       430        440        450        460        470        480 
GTMADDEMRT LNVPALQTHG LIFLWVTGRA MELGRECLER WGYKCVEEII WVKTNQLQRI 

       490        500        510        520        530        540 
IRTGRTGHWL NHSKEHCLVG IKGSPEVNRN IDTNVIVSEV RETSRKPDEM YAMMERISPG 

       550        560        570        580        590        600 
TRKVELFARM HNTHAGWMSL GNQLSGVRLV DEGLRARFKA AYPDVEVQPA SPSRASAMEL 

       610 
DSSVAAQTTT SAMM 

« Hide

References

[1]The International Medicago Genome Annotation Group
Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC148918 Genomic DNA. Translation: ABD28511.1.
RefSeqXP_003597586.1. XM_003597538.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID11429893.
KEGGmtr:MTR_2g099870.

Phylogenomic databases

KOK05925.

Family and domain databases

InterProIPR007757. MT-A70-like.
[Graphical view]
PfamPF05063. MT-A70. 1 hit.
[Graphical view]
PROSITEPS51143. MT_A70. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTA70_MEDTR
AccessionPrimary (citable) accession number: Q2HVD6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: March 21, 2006
Last modified: April 16, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families