Q2HRC6 (Q2HRC6_HHV8P) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ORF2 EMBL ABD28857.1

Gene names

Name:

ORF2 EMBL ABD28857.1

Organism

Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's sarcoma-associated herpesvirus) [Reference proteome]

Taxonomic identifier

868565 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Herpesvirales › Herpesviridae › Gammaherpesvirinae › Rhadinovirus › Human herpesvirus 8

Virus host

Homo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length	210 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dihydrofolate reductase family. RuleBase RU004474

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2HRC6 [UniParc]. Last modified March 21, 2006. Version 1. Checksum: 1F7EC5D5D82690D2	FASTA	210	23,354
	10 20 30 40 50 60 MDPTLYCVVA VDTKLGIGKN RCLPWPALRG DMRRFRQLTT DCAPGKQNMV VMGRRTWLSI 70 80 90 100 110 120 PAGCRPLAGR INVVLSRTLE TPPPGAHFLA SSLDAALGLA RSPELAQQID KVWVIGGGNL 130 140 150 160 170 180 YREALTGPWP VRLFLTRVLH DFACDVFLSH DSLAAYARVN PKPGEQERVF QERGIFYMFE 190 200 210 TYIKVTQSSD TALPDLERPR PATPPFSETS

References

[1]	"Identification of a spliced gene from Kaposi's sarcoma-associated herpesvirus encoding a protein with similarities to latent membrane proteins 1 and 2A of Epstein-Barr virus." Glenn M., Rainbow L., Aurade F., Davison A., Schulz T.F. J. Virol. 73:6953-6963(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Isolate GK18.
[2]	"Kaposi's sarcoma-associated herpesvirus immune modulation: an overview." Rezaee S.A.R., Cunningham C., Davison A.J., Blackbourn D.J. J. Gen. Virol. 87:1781-1804(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Isolate GK18.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF148805 Genomic DNA. Translation: ABD28857.1.
RefSeq	YP_001129359.1. NC_009333.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4961454.
Phylogenomic databases
ProtClustDB	CLSP2509646.
Family and domain databases
Gene3D	3.40.430.10. 1 hit.
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2HRC6_HHV8P

Accession

Primary (citable) accession number: Q2HRC6

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2006
Last sequence update:	March 21, 2006
Last modified:	April 3, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)