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Q2HJ94 (DNJA2_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DnaJ homolog subfamily A member 2
Gene names
Name:DNAJA2
OrganismBos taurus (Bovine) [Reference proteome]
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length412 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Co-chaperone of Hsc70 By similarity.

Subcellular location

Membrane; Lipid-anchor Potential.

Post-translational modification

Farnesylated By similarity.

Sequence similarities

Contains 1 CR-type zinc finger.

Contains 1 J domain.

Ontologies

Keywords
   Cellular componentMembrane
   DomainRepeat
Zinc-finger
   LigandMetal-binding
Zinc
   Molecular functionChaperone
   PTMLipoprotein
Methylation
Phosphoprotein
Prenylation
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: InterPro

response to heat

Inferred from electronic annotation. Source: InterPro

   Cellular_componentmembrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: InterPro

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 409409DnaJ homolog subfamily A member 2
PRO_0000290026
Propeptide410 – 4123Removed in mature form By similarity
PRO_0000396757

Regions

Domain8 – 7063J
Repeat143 – 1508CXXCXGXG motif
Repeat159 – 1668CXXCXGXG motif
Repeat186 – 1938CXXCXGXG motif
Repeat202 – 2098CXXCXGXG motif
Zinc finger130 – 21485CR-type

Sites

Metal binding1431Zinc 1 By similarity
Metal binding1461Zinc 1 By similarity
Metal binding1591Zinc 2 By similarity
Metal binding1621Zinc 2 By similarity
Metal binding1861Zinc 2 By similarity
Metal binding1891Zinc 2 By similarity
Metal binding2021Zinc 1 By similarity
Metal binding2051Zinc 1 By similarity

Amino acid modifications

Modified residue781Phosphoserine By similarity
Modified residue4091Cysteine methyl ester By similarity
Lipidation4091S-farnesyl cysteine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2HJ94 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: 27674EA20658ADE0

FASTA41245,762
        10         20         30         40         50         60 
MANVADTKLY DILGVPPGAS ENELKKAYRK LAKEYHPDKN PNAGDKFKEI SFAYEVLSNP 

        70         80         90        100        110        120 
EKRELYDRYG EQGLREGSGG GGGMDDIFSH IFGGGLFSFM GNQSRSRNGR RRGEDMMHPL 

       130        140        150        160        170        180 
KVSLEDLYNG KTTKLQLSKN VLCSACSGQG GKSGAVQKCS ACRGRGVRIM IRQLAPGMVQ 

       190        200        210        220        230        240 
QMQSVCSDCN GEGEVINEKD RCKKCEGKKV IKEVKILEVH VDKGMKHGQR ITFTGEADQA 

       250        260        270        280        290        300 
PGVEPGDIVL LLQEKEHEVF QRDGNDLHMT YKIGLVEALC GFQFTFKHLD GRQIVVKYPP 

       310        320        330        340        350        360 
GKVIEPGCVR VVRGEGMPQY RNPFEKGDLY IKFDVQFPEN NWINPDKLSE LEDLLPSRPE 

       370        380        390        400        410 
VPNIIGDTEE VELQEFDSTR GSGGGQRREA YNDSSDEESS SHHGPGVQCA HQ

« Hide

References

[1]NIH - Mammalian Gene Collection (MGC) project
Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Hereford.
Tissue: Uterus.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC113244 mRNA. Translation: AAI13245.1.
IPIIPI00733615.
RefSeqNP_001035581.1. NM_001040491.1.
UniGeneBt.7595.

3D structure databases

ProteinModelPortalQ2HJ94.
SMRQ2HJ94. Positions 6-70.
ModBaseSearch...

Proteomic databases

PRIDEQ2HJ94.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSBTAT00000004890; ENSBTAP00000004890; ENSBTAG00000003757.
GeneID360006.
KEGGbta:360006.

Organism-specific databases

CTD10294.

Phylogenomic databases

eggNOGCOG0484.
GeneTreeENSGT00490000043321.
HOGENOMHOG000226718.
HOVERGENHBG066727.
InParanoidQ2HJ94.
KOK09503.
OMAIPDPCHQ.
OrthoDBEOG4T783H.

Family and domain databases

Gene3D1.10.287.110. 1 hit.
2.10.230.10. 1 hit.
InterProIPR012724. DnaJ.
IPR002939. DnaJ_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR008971. HSP40/DnaJ_pept-bd.
IPR001305. HSP_DnaJ_Cys-rich_dom.
[Graphical view]
PfamPF00226. DnaJ. 1 hit.
PF01556. DnaJ_C. 1 hit.
PF00684. DnaJ_CXXCXGXG. 1 hit.
[Graphical view]
PRINTSPR00625. JDOMAIN.
SMARTSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMSSF46565. DnaJ_N. 1 hit.
SSF49493. HSP40_DnaJ_pep. 2 hits.
SSF57938. HSP_DnaJ_cys-rich. 1 hit.
PROSITEPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
PS51188. ZF_CR. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20812768.

Entry information

Entry nameDNJA2_BOVIN
AccessionPrimary (citable) accession number: Q2HJ94
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: March 21, 2006
Last modified: April 3, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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