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Q2HFZ9

- SSU72_CHAGB

UniProt

Q2HFZ9 - SSU72_CHAGB

Protein

RNA polymerase II subunit A C-terminal domain phosphatase SSU72

Gene

SSU72

Organism
Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (21 Mar 2006)
      Previous versions | rss
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    Functioni

    Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).By similarity
    Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs By similarity.By similarity

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    GO - Molecular functioni

    1. phosphoprotein phosphatase activity Source: UniProtKB-KW

    GO - Biological processi

    1. mRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Biological processi

    mRNA processing

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (EC:3.1.3.16)
    Short name:
    CTD phosphatase SSU72
    Alternative name(s):
    Suppressor of SUA7 protein 2 homolog
    Gene namesi
    Name:SSU72
    ORF Names:CHGG_00855
    OrganismiChaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)
    Taxonomic identifieri306901 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesChaetomiaceaeChaetomium
    ProteomesiUP000001056: Unassembled WGS sequence

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 257257RNA polymerase II subunit A C-terminal domain phosphatase SSU72PRO_0000255606Add
    BLAST

    Interactioni

    Subunit structurei

    Component of the cleavage and polyadenylation factor (CPF) complex.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ2HFZ9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the SSU72 phosphatase family.Curated

    Phylogenomic databases

    OrthoDBiEOG7GTTG0.

    Family and domain databases

    InterProiIPR006811. RNA_pol_II_suA.
    [Graphical view]
    PANTHERiPTHR20383. PTHR20383. 1 hit.
    PfamiPF04722. Ssu72. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2HFZ9-1 [UniParc]FASTAAdd to Basket

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    METANGNAGS AATAQNGQQE DASGFKLKFC TVCASNQNRS MEGHLRLAQA    50
    NYPVISFGTG SLVRLPGPTI TQPNVYKFNE TSYDSIYREL EAKDPRLYRA 100
    NGLLNMLGRN RVIKWGPERW QDWQVGMPRV KHEKDQGSIG MEAGVPDIVI 150
    TCEERCWDAV VDDLLNRGSP LNRPVHVINI DIKDNHQDAS IGGGAMVDLA 200
    DSLNRAAMEE RDKVGAAVFD AGGAASRASF DERVPEVLGE WQERWPGLPS 250
    TWTLSWF 257
    Length:257
    Mass (Da):28,393
    Last modified:March 21, 2006 - v1
    Checksum:iC629C0EEBBDCD527
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH408029 Genomic DNA. Translation: EAQ92620.1.
    RefSeqiXP_001220076.1. XM_001220075.1.

    Genome annotation databases

    GeneIDi4388085.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH408029 Genomic DNA. Translation: EAQ92620.1 .
    RefSeqi XP_001220076.1. XM_001220075.1.

    3D structure databases

    ProteinModelPortali Q2HFZ9.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 4388085.

    Phylogenomic databases

    OrthoDBi EOG7GTTG0.

    Family and domain databases

    InterProi IPR006811. RNA_pol_II_suA.
    [Graphical view ]
    PANTHERi PTHR20383. PTHR20383. 1 hit.
    Pfami PF04722. Ssu72. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970.

    Entry informationi

    Entry nameiSSU72_CHAGB
    AccessioniPrimary (citable) accession number: Q2HFZ9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: March 21, 2006
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3