ID   DCD_ANAPZ               Reviewed;         185 AA.
AC   Q2GLJ4;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=Deoxycytidine triphosphate deaminase;
DE            Short=dCTP deaminase;
DE            EC=3.5.4.13;
GN   Name=dcd; OrderedLocusNames=APH_0130;
OS   Anaplasma phagocytophilum (strain HZ).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Anaplasma; phagocytophilum group.
OX   NCBI_TaxID=212042;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16482227; DOI=10.1371/journal.pgen.0020021;
RA   Dunning Hotopp J.C., Lin M., Madupu R., Crabtree J., Angiuoli S.V.,
RA   Eisen J.A., Seshadri R., Ren Q., Wu M., Utterback T.R., Smith S.,
RA   Lewis M., Khouri H., Zhang C., Niu H., Lin Q., Ohashi N., Zhi N.,
RA   Nelson W.C., Brinkac L.M., Dodson R.J., Rosovitz M.J., Sundaram J.P.,
RA   Daugherty S.C., Davidsen T., Durkin A.S., Gwinn M.L., Haft D.H.,
RA   Selengut J.D., Sullivan S.A., Zafar N., Zhou L., Benahmed F.,
RA   Forberger H., Halpin R., Mulligan S., Robinson J., White O.,
RA   Rikihisa Y., Tettelin H.;
RT   "Comparative genomics of emerging human ehrlichiosis agents.";
RL   PLoS Genet. 2:208-222(2006).
CC   -!- CATALYTIC ACTIVITY: dCTP + H(2)O = dUTP + NH(3).
CC   -!- PATHWAY: Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP
CC       (dUTP route): step 1/2.
CC   -!- SIMILARITY: Belongs to the dCTP deaminase family.
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DR   EMBL; CP000235; ABD43468.1; -; Genomic_DNA.
DR   RefSeq; YP_504757.1; -.
DR   GeneID; 3930370; -.
DR   GenomeReviews; CP000235_GR; APH_0130.
DR   KEGG; aph:APH_0130; -.
DR   NMPDR; fig|212042.5.peg.125; -.
DR   TIGR; APH_0130; -.
DR   HOGENOM; Q2GLJ4; -.
DR   OMA; Q2GLJ4; CAQVLFF.
DR   BioCyc; APHA212042:APH_0130-MON; -.
DR   GO; GO:0008829; F:dCTP deaminase activity; IEA:HAMAP.
DR   GO; GO:0006229; P:dUTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0009220; P:pyrimidine ribonucleotide biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00146; -; 1.
DR   InterPro; IPR011962; dCTP_deam.
DR   ProDom; PD004900; dCTP_deaminase; 1.
DR   TIGRFAMs; TIGR02274; dCTP_deam; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Nucleotide metabolism.
FT   CHAIN         1    185       Deoxycytidine triphosphate deaminase.
FT                                /FTId=PRO_1000009677.
SQ   SEQUENCE   185 AA;  20591 MW;  CEB4032A48EEE38F CRC64;
     MSVMPDHWIK ERALKDGMIS PFVDHKEGTG VLSYGLSSYG YDARLDNKFK IFANTHSVVV
     DPKNFSQDSF VDREGDFCII PPNSFMLAKT VEYFNIPRDV MVVCVGKSTY ARCGIVVNVT
     PLEPGWSGYV TLEFSNTSPL PVKVYAFEGA CQFLFFSGKE RCSKSYDEAG GKYMGQSDVT
     LPIIS
//