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Q2GKX4

- Q2GKX4_ANAPZ

UniProt

Q2GKX4 - Q2GKX4_ANAPZ

Protein

Superoxide dismutase

Gene

sodB

Organism
Anaplasma phagocytophilum (strain HZ)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (21 Mar 2006)
      Previous versions | rss
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    Functioni

    Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation
    Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.

    Catalytic activityi

    2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi24 – 241Iron; via tele nitrogenImported
    Metal bindingi80 – 801Iron; via tele nitrogenImported
    Metal bindingi165 – 1651IronImported
    Metal bindingi169 – 1691Iron; via tele nitrogenImported

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. superoxide dismutase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationImported

    Keywords - Ligandi

    IronImported, Metal-bindingImported

    Enzyme and pathway databases

    BioCyciAPHA212042:GHPM-370-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
    Gene namesi
    Name:sodBImported
    Ordered Locus Names:APH_0371Imported
    OrganismiAnaplasma phagocytophilum (strain HZ)Imported
    Taxonomic identifieri212042 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeAnaplasmaphagocytophilum group
    ProteomesiUP000001943: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi212042.APH_0371.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3JS4X-ray1.95A/B/C/D1-206[»]
    ProteinModelPortaliQ2GKX4.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ2GKX4.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0605.
    HOGENOMiHOG000013584.
    KOiK04564.
    OMAiWTWLVKG.
    OrthoDBiEOG63NMNT.

    Family and domain databases

    InterProiIPR001189. Mn/Fe_SOD.
    IPR019833. Mn/Fe_SOD_BS.
    IPR019832. Mn/Fe_SOD_C.
    IPR019831. Mn/Fe_SOD_N.
    [Graphical view]
    PANTHERiPTHR11404. PTHR11404. 1 hit.
    PfamiPF02777. Sod_Fe_C. 1 hit.
    PF00081. Sod_Fe_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000349. SODismutase. 1 hit.
    PRINTSiPR01703. MNSODISMTASE.
    SUPFAMiSSF46609. SSF46609. 1 hit.
    SSF54719. SSF54719. 1 hit.
    PROSITEiPS00088. SOD_MN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2GKX4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFELSDLPYE GLEPYISSHL LDRHYNGHHK TYVDVLNKLV VGTEFEGLGN    50
    ESLGDIVVKA HNSGSAGRAI FNNAAQIWNH DFYWQSMKPN GGGNPPEKLR 100
    EMIEHSFGSV EGFNNAFTTS GLGQFGSGWV WLVYDEDAKA LKVVSTANAD 150
    SPLLTQGQLP LATMDVWEHA YYLDYLNLRK KYIDVFLEHL LNWDFVLGRL 200
    EDAGVL 206
    Length:206
    Mass (Da):23,167
    Last modified:March 21, 2006 - v1
    Checksum:iA7C3846EED519C5B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000235 Genomic DNA. Translation: ABD43382.1.
    RefSeqiYP_504977.1. NC_007797.1.

    Genome annotation databases

    EnsemblBacteriaiABD43382; ABD43382; APH_0371.
    GeneIDi3929965.
    KEGGiaph:APH_0371.
    PATRICi20949348. VBIAnaPha602_0394.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000235 Genomic DNA. Translation: ABD43382.1 .
    RefSeqi YP_504977.1. NC_007797.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3JS4 X-ray 1.95 A/B/C/D 1-206 [» ]
    ProteinModelPortali Q2GKX4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 212042.APH_0371.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABD43382 ; ABD43382 ; APH_0371 .
    GeneIDi 3929965.
    KEGGi aph:APH_0371.
    PATRICi 20949348. VBIAnaPha602_0394.

    Phylogenomic databases

    eggNOGi COG0605.
    HOGENOMi HOG000013584.
    KOi K04564.
    OMAi WTWLVKG.
    OrthoDBi EOG63NMNT.

    Enzyme and pathway databases

    BioCyci APHA212042:GHPM-370-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q2GKX4.

    Family and domain databases

    InterProi IPR001189. Mn/Fe_SOD.
    IPR019833. Mn/Fe_SOD_BS.
    IPR019832. Mn/Fe_SOD_C.
    IPR019831. Mn/Fe_SOD_N.
    [Graphical view ]
    PANTHERi PTHR11404. PTHR11404. 1 hit.
    Pfami PF02777. Sod_Fe_C. 1 hit.
    PF00081. Sod_Fe_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000349. SODismutase. 1 hit.
    PRINTSi PR01703. MNSODISMTASE.
    SUPFAMi SSF46609. SSF46609. 1 hit.
    SSF54719. SSF54719. 1 hit.
    PROSITEi PS00088. SOD_MN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HZImported.
    2. "Crystal structure of Iron superoxide dismutase from Anaplasma phagocytophilum."
      Seattle Structural Genomics Center for Infectious Disease (SSGCID)
      Edwards T.E., Staker B.L.
      Submitted (SEP-2009) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) IN COMPLEX WITH IRON.

    Entry informationi

    Entry nameiQ2GKX4_ANAPZ
    AccessioniPrimary (citable) accession number: Q2GKX4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 21, 2006
    Last sequence update: March 21, 2006
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3