Superoxide dismutase - Anaplasma phagocytophilum (strain HZ)

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Q2GKX4 (Q2GKX4_ANAPZ) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 56. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Recommended name:
Superoxide dismutase RuleBase RU000414
EC=1.15.1.1 RuleBase RU000414

Gene names

Name:	sodB EMBL ABD43382.1
Ordered Locus Names:	APH_0371 EMBL ABD43382.1

Organism

Anaplasma phagocytophilum (strain HZ) [Complete proteome] [HAMAP] EMBL ABD43382.1

Taxonomic identifier

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Anaplasma › phagocytophilum group ›

Protein attributes

Sequence length	206 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity. RuleBase RU000414
Catalytic activity	2 superoxide + 2 H⁺ = O₂ + H₂O₂. RuleBase RU000414
Sequence similarities	Belongs to the iron/manganese superoxide dismutase family. RuleBase RU004477

Ontologies

Keywords
Ligand	Iron PDB 3JS4 Metal-binding PDB 3JS4
Molecular function	Oxidoreductase RuleBase RU000414 EMBL ABD43382.1
Technical term	3D-structure PDB 3JS4 Complete proteome
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

1

Iron; via tele nitrogen PDB 3JS4

Metal binding

1

Iron; via tele nitrogen PDB 3JS4

Metal binding

1

Metal binding

1

Iron; via tele nitrogen PDB 3JS4

Sequences

Sequence

Length

Mass (Da)

Tools

Q2GKX4 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: A7C3846EED519C5B
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206

23,167

        10         20         30         40         50         60 
MFELSDLPYE GLEPYISSHL LDRHYNGHHK TYVDVLNKLV VGTEFEGLGN ESLGDIVVKA 

        70         80         90        100        110        120 
HNSGSAGRAI FNNAAQIWNH DFYWQSMKPN GGGNPPEKLR EMIEHSFGSV EGFNNAFTTS 

       130        140        150        160        170        180 
GLGQFGSGWV WLVYDEDAKA LKVVSTANAD SPLLTQGQLP LATMDVWEHA YYLDYLNLRK 

       190        200 
KYIDVFLEHL LNWDFVLGRL EDAGVL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Comparative genomics of emerging human ehrlichiosis agents." Hotopp J.C., Lin M., Madupu R., Crabtree J., Angiuoli S.V., Eisen J.A., Seshadri R., Ren Q., Wu M., Utterback T.R., Smith S., Lewis M., Khouri H., Zhang C., Niu H., Lin Q., Ohashi N., Zhi N. Tettelin H. PLoS Genet. 2:E21-E21(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HZ EMBL ABD43382.1.
[2]	"Crystal structure of Iron superoxide dismutase from Anaplasma phagocytophilum." Seattle Structural Genomics Center for Infectious Disease (SSGCID) Edwards T.E., Staker B.L. Submitted (SEP-2009) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) IN COMPLEX WITH IRON.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000235 Genomic DNA. Translation: ABD43382.1.

RefSeq

YP_504977.1. NC_007797.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3JS4	X-ray	1.95	A/B/C/D	1-206	[»]

ProteinModelPortal

ModBase

Protein-protein interaction databases

STRING

212042.APH_0371.

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

EnsemblBacteria

ABD43382; ABD43382; APH_0371.

GeneID

KEGG

PATRIC

20949348. VBIAnaPha602_0394.

Organism-specific databases

CMR

Phylogenomic databases

eggNOG

HOGENOM

KO

OMA

ProtClustDB

Enzyme and pathway databases

BioCyc

APHA212042:GHPM-370-MONOMER.

Family and domain databases

InterPro

IPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]

PANTHER

PTHR11404. PTHR11404. 1 hit.

Pfam

PF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]

PIRSF

PIRSF000349. SODismutase. 1 hit.

PRINTS

PR01703. MNSODISMTASE.

SUPFAM

SSF46609. SODismutase. 1 hit.
SSF54719. SODismutase. 1 hit.

PROSITE

PS00088. SOD_MN. 1 hit.
[Graphical view]

ProtoNet

Other

EvolutionaryTrace

Entry information

Entry name

Q2GKX4_ANAPZ

Accession

Primary (citable) accession number: Q2GKX4

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2006
Last sequence update:	March 21, 2006
Last modified:	May 29, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info