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Q2GKX4 (Q2GKX4_ANAPZ) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Superoxide dismutase RuleBase RU000414

EC=1.15.1.1 RuleBase RU000414
Gene names
Name:sodB EMBL ABD43382.1
Ordered Locus Names:APH_0371 EMBL ABD43382.1
OrganismAnaplasma phagocytophilum (strain HZ) [Complete proteome] [HAMAP] EMBL ABD43382.1
Taxonomic identifier212042 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeAnaplasmaphagocytophilum group

Protein attributes

Sequence length206 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.

Catalytic activity

2 superoxide + 2 H+ = O2 + H2O2.

Sequence similarities

Belongs to the iron/manganese superoxide dismutase family. RuleBase RU004477

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding241Iron; via tele nitrogen PDB 3JS4
Metal binding801Iron; via tele nitrogen PDB 3JS4
Metal binding1521Sodium; via carbonyl oxygen PDB 3JS4
Metal binding1551Sodium; via carbonyl oxygen PDB 3JS4
Metal binding1581Sodium; via carbonyl oxygen PDB 3JS4
Metal binding1651Iron PDB 3JS4
Metal binding1691Iron; via tele nitrogen PDB 3JS4

Sequences

Sequence LengthMass (Da)Tools
Q2GKX4 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: A7C3846EED519C5B

FASTA20623,167
        10         20         30         40         50         60 
MFELSDLPYE GLEPYISSHL LDRHYNGHHK TYVDVLNKLV VGTEFEGLGN ESLGDIVVKA 

        70         80         90        100        110        120 
HNSGSAGRAI FNNAAQIWNH DFYWQSMKPN GGGNPPEKLR EMIEHSFGSV EGFNNAFTTS 

       130        140        150        160        170        180 
GLGQFGSGWV WLVYDEDAKA LKVVSTANAD SPLLTQGQLP LATMDVWEHA YYLDYLNLRK 

       190        200 
KYIDVFLEHL LNWDFVLGRL EDAGVL 

« Hide

References

« Hide 'large scale' references
[1]"Comparative genomics of emerging human ehrlichiosis agents."
Dunning Hotopp J.C., Lin M., Madupu R., Crabtree J., Angiuoli S.V., Eisen J.A., Seshadri R., Ren Q., Wu M., Utterback T.R., Smith S., Lewis M., Khouri H., Zhang C., Niu H., Lin Q., Ohashi N., Zhi N. expand/collapse author list , Nelson W., Brinkac L.M., Dodson R.J., Rosovitz M.J., Sundaram J., Daugherty S.C., Davidsen T., Durkin A.S., Gwinn M., Haft D.H., Selengut J.D., Sullivan S.A., Zafar N., Zhou L., Benahmed F., Forberger H., Halpin R., Mulligan S., Robinson J., White O., Rikihisa Y., Tettelin H.
PLoS Genet. 2:E21-E21(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HZ EMBL ABD43382.1.
[2]"Crystal structure of Iron superoxide dismutase from Anaplasma phagocytophilum."
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Edwards T.E., Staker B.L.
Submitted (SEP-2009) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) IN COMPLEX WITH IRON AND SODIUM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000235 Genomic DNA. Translation: ABD43382.1.
RefSeqYP_504977.1. NC_007797.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3JS4X-ray1.95A/B/C/D1-206[»]
ProteinModelPortalQ2GKX4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING212042.APH_0371.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABD43382; ABD43382; APH_0371.
GeneID3929965.
KEGGaph:APH_0371.
PATRIC20949348. VBIAnaPha602_0394.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0605.
HOGENOMHOG000013584.
KOK04564.
OMAWTWLVKG.
OrthoDBEOG63NMNT.

Enzyme and pathway databases

BioCycAPHA212042:GHPM-370-MONOMER.

Family and domain databases

InterProIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERPTHR11404. PTHR11404. 1 hit.
PfamPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFPIRSF000349. SODismutase. 1 hit.
PRINTSPR01703. MNSODISMTASE.
SUPFAMSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ2GKX4.

Entry information

Entry nameQ2GKX4_ANAPZ
AccessionPrimary (citable) accession number: Q2GKX4
Entry history
Integrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: July 9, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)