ID   PSD_ANAPZ               Reviewed;         227 AA.
AC   Q2GKG5;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=Phosphatidylserine decarboxylase proenzyme;
DE            EC=4.1.1.65;
DE   Contains:
DE     RecName: Full=Phosphatidylserine decarboxylase alpha chain;
DE   Contains:
DE     RecName: Full=Phosphatidylserine decarboxylase beta chain;
GN   Name=psd; OrderedLocusNames=APH_0544;
OS   Anaplasma phagocytophilum (strain HZ).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Anaplasma; phagocytophilum group.
OX   NCBI_TaxID=212042;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16482227; DOI=10.1371/journal.pgen.0020021;
RA   Dunning Hotopp J.C., Lin M., Madupu R., Crabtree J., Angiuoli S.V.,
RA   Eisen J.A., Seshadri R., Ren Q., Wu M., Utterback T.R., Smith S.,
RA   Lewis M., Khouri H., Zhang C., Niu H., Lin Q., Ohashi N., Zhi N.,
RA   Nelson W.C., Brinkac L.M., Dodson R.J., Rosovitz M.J., Sundaram J.P.,
RA   Daugherty S.C., Davidsen T., Durkin A.S., Gwinn M.L., Haft D.H.,
RA   Selengut J.D., Sullivan S.A., Zafar N., Zhou L., Benahmed F.,
RA   Forberger H., Halpin R., Mulligan S., Robinson J., White O.,
RA   Rikihisa Y., Tettelin H.;
RT   "Comparative genomics of emerging human ehrlichiosis agents.";
RL   PLoS Genet. 2:208-222(2006).
CC   -!- CATALYTIC ACTIVITY: Phosphatidyl-L-serine =
CC       phosphatidylethanolamine + CO(2).
CC   -!- COFACTOR: Pyruvoyl group (By similarity).
CC   -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC       biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol:
CC       step 2/2.
CC   -!- SIMILARITY: Belongs to the phosphatidylserine decarboxylase
CC       family. Type 3 subfamily.
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DR   EMBL; CP000235; ABD43741.1; -; Genomic_DNA.
DR   RefSeq; YP_505136.1; -.
DR   GeneID; 3931063; -.
DR   GenomeReviews; CP000235_GR; APH_0544.
DR   KEGG; aph:APH_0544; -.
DR   NMPDR; fig|212042.5.peg.535; -.
DR   TIGR; APH_0544; -.
DR   HOGENOM; Q2GKG5; -.
DR   OMA; Q2GKG5; DKASEDN.
DR   BioCyc; APHA212042:APH_0544-MON; -.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:HAMAP.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00664; -; 1.
DR   InterPro; IPR003817; PS_Dcarbxylase.
DR   InterPro; IPR004428; PtdSer_deCO2ase_related.
DR   Pfam; PF02666; PS_Dcarbxylase; 1.
DR   TIGRFAMs; TIGR00164; PS_decarb_rel; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Decarboxylase; Lyase; Phospholipid biosynthesis;
KW   Pyruvate; Zymogen.
FT   CHAIN         1    180       Phosphatidylserine decarboxylase beta
FT                                chain (By similarity).
FT                                /FTId=PRO_0000262181.
FT   CHAIN       181    227       Phosphatidylserine decarboxylase alpha
FT                                chain (By similarity).
FT                                /FTId=PRO_0000262182.
FT   SITE        180    181       Cleavage (non-hydrolytic) (By
FT                                similarity).
FT   MOD_RES     181    181       Pyruvic acid (Ser) (By similarity).
SQ   SEQUENCE   227 AA;  24487 MW;  3C2D525B22CC4CF7 CRC64;
     MCFPNIHKQG YPFIAIAFVL TCIGFAFSFG LGLVFQIITV LCACFFRNPD RIVPVDDKLI
     ISPADGLVTS VAEVESPIEA GKMVTRVSVF LSILNVHVNR APVSGSVKLV EHRPGRFSPA
     CTDGSTSENE RVRSVIESTF GNHNIVIEQV AGVLARRIVC DLKVGDNVKL GSRMGIIRFG
     SRVNVYVPAG VPVLVTEGHT LVGGETVIAD LDSERTAGYP RATFEKV
//