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Q2GKG5 (PSD_ANAPZ) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:APH_0544
OrganismAnaplasma phagocytophilum (strain HZ) [Complete proteome] [HAMAP]
Taxonomic identifier212042 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Anaplasma › phagocytophilum group

Protein attributes

Sequence length227 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 180180Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000262181
Chain181 – 22747Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000262182

Sites

Site180 – 1812Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1811Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2GKG5 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: 3C2D525B22CC4CF7

FASTA22724,487
        10         20         30         40         50         60 
MCFPNIHKQG YPFIAIAFVL TCIGFAFSFG LGLVFQIITV LCACFFRNPD RIVPVDDKLI 

        70         80         90        100        110        120 
ISPADGLVTS VAEVESPIEA GKMVTRVSVF LSILNVHVNR APVSGSVKLV EHRPGRFSPA 

       130        140        150        160        170        180 
CTDGSTSENE RVRSVIESTF GNHNIVIEQV AGVLARRIVC DLKVGDNVKL GSRMGIIRFG 

       190        200        210        220 
SRVNVYVPAG VPVLVTEGHT LVGGETVIAD LDSERTAGYP RATFEKV

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000235 Genomic DNA. Translation: ABD43741.1.
RefSeqYP_505136.1. NC_007797.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ2GKG5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3931063.
GenomeReviewsGene locus APH_0544 in contig CP000235_GR.
KEGGaph:APH_0544.
NMPDRfig|212042.5.peg.535.
PATRIC20949744. VBIAnaPha602_0588.
TIGRAPH_0544.

Phylogenomic databases

eggNOGCOG0688.
HOGENOMHBG541103.
OMAIFMSVFN.
PhylomeDBQ2GKG5.
ProtClustDBPRK05305.

Enzyme and pathway databases

BioCycAPHA212042:APH_0544-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_ANAPZ
AccessionPrimary (citable) accession number: Q2GKG5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: March 21, 2006
Last modified: January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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