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Q2GK20

- SYR_ANAPZ

UniProt

Q2GK20 - SYR_ANAPZ

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Anaplasma phagocytophilum (strain HZ)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAPHA212042:GHPM-700-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:APH_0700
OrganismiAnaplasma phagocytophilum (strain HZ)
Taxonomic identifieri212042 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeAnaplasmaphagocytophilum group
ProteomesiUP000001943: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 580580Arginine--tRNA ligasePRO_0000241977Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi212042.APH_0700.

Structurei

3D structure databases

ProteinModelPortaliQ2GK20.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi137 – 14711"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247214.
KOiK01887.
OMAiLCNVLAK.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2GK20-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLLDDKILDI FGFFRNAIEE RIRAVWSGDN IPESLFKRII VGPPAQPKHG
60 70 80 90 100
DLYTNAALIL GKFDKKNPME LASTLCNAFE NIEGIESINV VAPGFINFHC
110 120 130 140 150
VNSVWHGVVR NINKLGREYG RTDLGHNKKV NIEFVSANPT GPLHIGHARG
160 170 180 190 200
AVFGDVLSNL LKWVGYDVIK EYYVNDAGSQ VKTLVSSVFL RYKEALGEEI
210 220 230 240 250
TIGAGLYPGE YLKPIARDLV EKYGSDLLNA SDKDEIIRSF TLSSMLNLIK
260 270 280 290 300
EDLALLGVEH DVFVSESDLQ NRNVIEECVK YLRERGIIYE GVLEKPKRED
310 320 330 340 350
ELSEWQPRVQ MLFKSTEFGD DSDRALQKED GTWSYFAGDI GYHFHKISRG
360 370 380 390 400
FDSMIMTLGF DHKGYVSRLK AAVAALSNGK ASIDIKLYNL VNFLENGTPV
410 420 430 440 450
KMSKRKGEFL TVRDVIDEVG RDVARFMMLT RRNDVVLDFD FAKAREESKD
460 470 480 490 500
SQIFYIQYAH ARIRSIVRRC PELLAIEKID FSCVITEQEL SLLRLLSRWP
510 520 530 540 550
SVIKTSAENY EPHTIAFYLI EVAEAFHALW GCGNSDPSMR FIVEGDLHTT
560 570 580
SARIYIAIAV SHVIASGLDI FSITPSEEMR
Length:580
Mass (Da):65,545
Last modified:March 21, 2006 - v1
Checksum:iA5A0216ABAD6C597
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000235 Genomic DNA. Translation: ABD43701.1.
RefSeqiYP_505281.1. NC_007797.1.

Genome annotation databases

EnsemblBacteriaiABD43701; ABD43701; APH_0700.
GeneIDi3930454.
KEGGiaph:APH_0700.
PATRICi20950086. VBIAnaPha602_0753.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000235 Genomic DNA. Translation: ABD43701.1 .
RefSeqi YP_505281.1. NC_007797.1.

3D structure databases

ProteinModelPortali Q2GK20.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 212042.APH_0700.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABD43701 ; ABD43701 ; APH_0700 .
GeneIDi 3930454.
KEGGi aph:APH_0700.
PATRICi 20950086. VBIAnaPha602_0753.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247214.
KOi K01887.
OMAi LCNVLAK.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci APHA212042:GHPM-700-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HZ.

Entry informationi

Entry nameiSYR_ANAPZ
AccessioniPrimary (citable) accession number: Q2GK20
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: March 21, 2006
Last modified: October 29, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3