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Q2GJ61 (EFTU_ANAPZ) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor Tu

Short name=EF-Tu
Gene names
Name:tuf1
Synonyms:tuf-1
Ordered Locus Names:APH_0278
AND
Name:tuf2
Synonyms:tuf-2
Ordered Locus Names:APH_1032
OrganismAnaplasma phagocytophilum (strain HZ) [Complete proteome] [HAMAP]
Taxonomic identifier212042 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeAnaplasmaphagocytophilum group

Protein attributes

Sequence length393 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processGTP catabolic process

Inferred from electronic annotation. Source: GOC

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 393393Elongation factor Tu HAMAP-Rule MF_00118
PRO_0000337316

Regions

Nucleotide binding15 – 228GTP By similarity
Nucleotide binding79 – 835GTP By similarity
Nucleotide binding134 – 1374GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2GJ61 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: F07EF9769616EFE6

FASTA39342,858
        10         20         30         40         50         60 
MTEGRKPHIN VGTIGHVDHG KTTLTAALTT VLARKLSGAN KVVKYDEIDK APEEKARGIT 

        70         80         90        100        110        120 
ISTAHVEYET EGRHYAHVDC PGHADYIKNM ITGAAQMDVA ILVVSATDGA MPQTREHILL 

       130        140        150        160        170        180 
AKQVGVKDIV VWINKCDVVE DEEMLSLVDM EIRELLSQYG YDGDSIDAVR GSAVKALEED 

       190        200        210        220        230        240 
ADGPWSDKIM ELVGALEKIE LPMREKDKPF LMSVEDVFSI PGRGTVVTGR IERGVVRVGD 

       250        260        270        280        290        300 
KIDIVGLREL QSTVCTGVEM FHKALEAGEA GDNAGILLRG IKKEDVERGQ VLSAPGQMKS 

       310        320        330        340        350        360 
YKKFKAEVYV LKKEEGGRHT PFFANYQPQF YVRTTDVTGS ISLPAGVEMV MPGDNLSIEV 

       370        380        390 
ALDKPVAIDK GLRFAVREGG RTVGSGIITE ILE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000235 Genomic DNA. Translation: ABD44063.1.
CP000235 Genomic DNA. Translation: ABD44111.1.
RefSeqYP_504890.1. NC_007797.1.
YP_505590.1. NC_007797.1.

3D structure databases

ProteinModelPortalQ2GJ61.
SMRQ2GJ61. Positions 3-392.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING212042.APH_1032.

Proteomic databases

PRIDEQ2GJ61.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABD44063; ABD44063; APH_0278.
ABD44111; ABD44111; APH_1032.
GeneID3930524.
3930925.
KEGGaph:APH_0278.
aph:APH_1032.
PATRIC20949130. VBIAnaPha602_0287.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMASHIEYST.
OrthoDBEOG6R5C6X.
ProtClustDBPRK00049.

Enzyme and pathway databases

BioCycAPHA212042:GHPM-1032-MONOMER.
APHA212042:GHPM-277-MONOMER.

Family and domain databases

HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_ANAPZ
AccessionPrimary (citable) accession number: Q2GJ61
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 21, 2006
Last modified: February 19, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families