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Q2GJ61

- EFTU_ANAPZ

UniProt

Q2GJ61 - EFTU_ANAPZ

Protein

Elongation factor Tu

Gene

tuf1

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Organism
Anaplasma phagocytophilum (strain HZ)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (21 Mar 2006)
      Previous versions | rss
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    • Comment

    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi15 – 228GTPUniRule annotation
    Nucleotide bindingi79 – 835GTPUniRule annotation
    Nucleotide bindingi134 – 1374GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciAPHA212042:GHPM-1032-MONOMER.
    APHA212042:GHPM-277-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tuf1UniRule annotation
    Synonyms:tuf-1
    Ordered Locus Names:APH_0278
    AND
    Name:tuf2UniRule annotation
    Synonyms:tuf-2
    Ordered Locus Names:APH_1032
    OrganismiAnaplasma phagocytophilum (strain HZ)
    Taxonomic identifieri212042 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeAnaplasmaphagocytophilum group
    ProteomesiUP000001943: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 393393Elongation factor TuPRO_0000337316Add
    BLAST

    Proteomic databases

    PRIDEiQ2GJ61.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi212042.APH_1032.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2GJ61.
    SMRiQ2GJ61. Positions 3-392.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini6 – 204199tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni15 – 228G1By similarity
    Regioni58 – 625G2By similarity
    Regioni79 – 824G3By similarity
    Regioni134 – 1374G4By similarity
    Regioni172 – 1743G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0050.
    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiERKPHIN.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2GJ61-1 [UniParc]FASTAAdd to Basket

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    MTEGRKPHIN VGTIGHVDHG KTTLTAALTT VLARKLSGAN KVVKYDEIDK    50
    APEEKARGIT ISTAHVEYET EGRHYAHVDC PGHADYIKNM ITGAAQMDVA 100
    ILVVSATDGA MPQTREHILL AKQVGVKDIV VWINKCDVVE DEEMLSLVDM 150
    EIRELLSQYG YDGDSIDAVR GSAVKALEED ADGPWSDKIM ELVGALEKIE 200
    LPMREKDKPF LMSVEDVFSI PGRGTVVTGR IERGVVRVGD KIDIVGLREL 250
    QSTVCTGVEM FHKALEAGEA GDNAGILLRG IKKEDVERGQ VLSAPGQMKS 300
    YKKFKAEVYV LKKEEGGRHT PFFANYQPQF YVRTTDVTGS ISLPAGVEMV 350
    MPGDNLSIEV ALDKPVAIDK GLRFAVREGG RTVGSGIITE ILE 393
    Length:393
    Mass (Da):42,858
    Last modified:March 21, 2006 - v1
    Checksum:iF07EF9769616EFE6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000235 Genomic DNA. Translation: ABD44063.1.
    CP000235 Genomic DNA. Translation: ABD44111.1.
    RefSeqiYP_504890.1. NC_007797.1.
    YP_505590.1. NC_007797.1.

    Genome annotation databases

    EnsemblBacteriaiABD44063; ABD44063; APH_0278.
    ABD44111; ABD44111; APH_1032.
    GeneIDi3930524.
    3930925.
    KEGGiaph:APH_0278.
    aph:APH_1032.
    PATRICi20949130. VBIAnaPha602_0287.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000235 Genomic DNA. Translation: ABD44063.1 .
    CP000235 Genomic DNA. Translation: ABD44111.1 .
    RefSeqi YP_504890.1. NC_007797.1.
    YP_505590.1. NC_007797.1.

    3D structure databases

    ProteinModelPortali Q2GJ61.
    SMRi Q2GJ61. Positions 3-392.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 212042.APH_1032.

    Proteomic databases

    PRIDEi Q2GJ61.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABD44063 ; ABD44063 ; APH_0278 .
    ABD44111 ; ABD44111 ; APH_1032 .
    GeneIDi 3930524.
    3930925.
    KEGGi aph:APH_0278.
    aph:APH_1032.
    PATRICi 20949130. VBIAnaPha602_0287.

    Phylogenomic databases

    eggNOGi COG0050.
    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi ERKPHIN.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci APHA212042:GHPM-1032-MONOMER.
    APHA212042:GHPM-277-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HZ.

    Entry informationi

    Entry nameiEFTU_ANAPZ
    AccessioniPrimary (citable) accession number: Q2GJ61
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: March 21, 2006
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3