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Q2GHW4 (PTH_EHRCR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptidyl-tRNA hydrolase
Short name=PTH
EC=3.1.1.29
Gene names
Name:pth
Ordered Locus Names:ECH_0141
OrganismEhrlichia chaffeensis (strain Arkansas) [Complete proteome] [HAMAP]
Taxonomic identifier205920 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Ehrlichia

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP MF_00083

Catalytic activity

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00083

Subunit structure

Monomer By similarity. HAMAP MF_00083

Subcellular location

Cytoplasm By similarity HAMAP MF_00083.

Sequence similarities

Belongs to the PTH family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionaminoacyl-tRNA hydrolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 198198Peptidyl-tRNA hydrolase HAMAP MF_00083
PRO_0000264035

Sequences

Sequence LengthMass (Da)Tools
Q2GHW4 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: BAA597EA427AD012

FASTA19822,626
        10         20         30         40         50         60 
MFYLLAGLGN PGKKYELSRH NAGFMIVDAI ASEFYFPSFR ERHNALISIG NIKSHRVILV 

        70         80         90        100        110        120 
KPWTFMNNSG APIMSIASLY KIPLDNIIIF HDEVEINFCT IRVKKSGGNA GHNGLKSIDN 

       130        140        150        160        170        180 
LLGKDYWRVR FGIGRPINKT NLKIDLSYYV LSQFHNIKAV NNTILNIVEH ITLLLEKKPS 

       190 
MFMEKVKNLI KYEDIPTE

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000236 Genomic DNA. Translation: ABD45087.1.
RefSeqYP_506969.1. NC_007799.1.

3D structure databases

ProteinModelPortalQ2GHW4.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2GHW4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3927185.
GenomeReviewsGene locus ECH_0141 in contig CP000236_GR.
KEGGech:ECH_0141.
PATRIC20575827. VBIEhrCha103583_0121.
TIGRECH_0141.

Phylogenomic databases

eggNOGCOG0193.
HOGENOMHBG610927.
OMAFNILMNG.
PhylomeDBQ2GHW4.
ProtClustDBPRK05426.

Enzyme and pathway databases

BioCycECHA205920:ECH_0141-MONOMER.

Family and domain databases

HAMAPMF_00083. Pept_tRNA_hydro_bact.
[Tree]
InterProIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
Gene3DG3DSA:3.40.50.1470. Pept_tRNA_hydro. 1 hit.
KOK01056.
PANTHERPTHR17224. Pept_tRNA_hydro. 1 hit.
PfamPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMSSF53178. Pept_tRNA_hydro. 1 hit.
TIGRFAMsTIGR00447. Pth. 1 hit.
PROSITEPS01195. PEPT_TRNA_HYDROL_1. False negative.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePTH_EHRCR
AccessionPrimary (citable) accession number: Q2GHW4
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: March 21, 2006
Last modified: January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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