Q2GHG6 (Q2GHG6_EHRCR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase HAMAP MF_00146
Short name=dCTP deaminase HAMAP MF_00146
EC=3.5.4.13 HAMAP MF_00146

Gene names

Name:	dcd HAMAP MF_00146
Ordered Locus Names:	ECH_0296

Organism

Ehrlichia chaffeensis (strain Arkansas) [Complete proteome] [HAMAP]

Taxonomic identifier

205920 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Ehrlichia

Protein attributes

Sequence length	187 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146 SAAS SAAS011962
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146 SAAS SAAS011962
Sequence similarities	Belongs to the dCTP deaminase family. HAMAP MF_00146

Ontologies

Keywords
Biological process	Nucleotide metabolism HAMAP MF_00146 SAAS SAAS011962
Molecular function	Hydrolase HAMAP MF_00146 SAAS SAAS011962
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2GHG6 [UniParc]. Last modified March 21, 2006. Version 1. Checksum: 66065049F315F9B0	FASTA	187	21,086
	10 20 30 40 50 60 MSVMPDHWIK DKAIKEKMID PFIDYKRSSG ILSYGLSSYG YDARIDNKFK VFTNVNSVTV 70 80 90 100 110 120 DPKNFPLGSF IDKEEDVCII PPNSFVLAKT VEYFKIPKDI LVMCVGKSTY ARCGIVVNVT 130 140 150 160 170 180 PLEPGWEGYV TLEFSNTTPL PAKIYAFEGA CQFIFLKGDS QCNLSYNEMQ GKYMNQLDVT LPIVNNS

References

[1]

"Comparative genomics of emerging human ehrlichiosis agents." Dunning Hotopp J.C., Lin M., Madupu R., Crabtree J., Angiuoli S.V., Eisen J.A., Seshadri R., Ren Q., Wu M., Utterback T.R., Smith S., Lewis M., Khouri H., Zhang C., Niu H., Lin Q., Ohashi N., Zhi N. , Nelson W.C., Brinkac L.M., Dodson R.J., Rosovitz M.J., Sundaram J.P., Daugherty S.C., Davidsen T., Durkin A.S., Gwinn M.L., Haft D.H., Selengut J.D., Sullivan S.A., Zafar N., Zhou L., Benahmed F., Forberger H., Halpin R., Mulligan S., Robinson J., White O., Rikihisa Y., Tettelin H. PLoS Genet. 2:208-222(2006) [PubMed: 16482227] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000236 Genomic DNA. Translation: ABD45481.1.
RefSeq	YP_507117.1. NC_007799.1.
3D structure databases
ProteinModelPortal	Q2GHG6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2GHG6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3927502.
GenomeReviews	Gene locus ECH_0296 in contig CP000236_GR.
KEGG	ech:ECH_0296.
PATRIC	20576097. VBIEhrCha103583_0250.
TIGR	ECH_0296.
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HBG553199.
OMA	IFRHIPG.
PhylomeDB	Q2GHG6.
ProtClustDB	PRK00416.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
KO	K01494.
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2GHG6_EHRCR

Accession

Primary (citable) accession number: Q2GHG6

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2006
Last sequence update:	March 21, 2006
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)