Q2GFZ7 (Q2GFZ7_EHRCR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-polyprenylphenol 6-hydroxylase EMBL ABD45566.1
EC=1.14.13.- EMBL ABD45566.1

Gene names

Name:	ubiB EMBL ABD45566.1
Ordered Locus Names:	ECH_0840

Organism

Ehrlichia chaffeensis (strain Arkansas) [Complete proteome] [HAMAP] EMBL ABD45566.1

Taxonomic identifier

205920 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Ehrlichia › canis group › Ehrlichia chaffeensis

Protein attributes

Sequence length	480 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis By similarity. SAAS SAAS010232
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity SAAS SAAS010232. Cell inner membrane; Single-pass membrane protein By similarity SAAS SAAS010232.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis SAAS SAAS010232
Cellular component	Cell inner membrane SAAS SAAS010232 Cell membrane Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS010232
Molecular function	Oxidoreductase EMBL ABD45566.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ubiquinone biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW protein kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2GFZ7 [UniParc]. Last modified March 21, 2006. Version 1. Checksum: C773D8D1E970ED39	FASTA	480	55,357
	10 20 30 40 50 60 MLSTFSNIIS LLNILSVLVR YNILPYTYLF AKRSIRKKSR GEKIAMAMQK LGPIFIKFGQ 70 80 90 100 110 120 SISSRTDIIG EEIASHLLCL CDKLPAFPYV DVVKIVEEDF KCKINEVFCE FEQNPIAAAS 130 140 150 160 170 180 IAQVHKAKDI NGNVRAVKVL RPRIEKIFER DIKLMFWLAR VAQNFQSLQR FQLLQLVQTF 190 200 210 220 230 240 HEICKMEIDL RFEAANAEEL RSNIQSDKGC YVPEVDWTRT TRRVLTLEWI DAVPIYNVYK 250 260 270 280 290 300 SENCKALVEN LIFCFCNQVY RDRFFHADMH PGNLMVDAKG RVVIIDFGIV GRLDKATCMY 310 320 330 340 350 360 VTEILVGFLK RDYQYVADIH YRAGYVDAKY SNFVTACCAI GEPIVGKNTE NISISALLTQ 370 380 390 400 410 420 LFKVTADFNM KLQPQLFLLQ KTTVLIEGVC RQLCPEVNMW KIAELWMEKY AIEKNKYIQK 430 440 450 460 470 480 LKRSYLCQAI HDVPLFMKKV DKSLDLINNY QELSKAKTSI SRDVIWALIV LGLIIKLIIG

References

[1]

"Comparative genomics of emerging human ehrlichiosis agents." Hotopp J.C., Lin M., Madupu R., Crabtree J., Angiuoli S.V., Eisen J.A., Seshadri R., Ren Q., Wu M., Utterback T.R., Smith S., Lewis M., Khouri H., Zhang C., Niu H., Lin Q., Ohashi N., Zhi N. , Nelson W., Brinkac L.M., Dodson R.J., Rosovitz M.J., Sundaram J., Daugherty S.C., Davidsen T., Durkin A.S., Gwinn M., Haft D.H., Selengut J.D., Sullivan S.A., Zafar N., Zhou L., Benahmed F., Forberger H., Halpin R., Mulligan S., Robinson J., White O., Rikihisa Y., Tettelin H. PLoS Genet. 2:E21-E21(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Arkansas.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000236 Genomic DNA. Translation: ABD45566.1.
RefSeq	YP_507636.1. NC_007799.1.
3D structure databases
ProteinModelPortal	Q2GFZ7.
ModBase	Search...
Protein-protein interaction databases
STRING	205920.ECH_0840.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABD45566; ABD45566; ECH_0840.
GeneID	3927874.
KEGG	ech:ECH_0840.
PATRIC	20577094. VBIEhrCha103583_0730.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0661.
HOGENOM	HOG000264438.
KO	K03688.
OMA	SELAENM.
ProtClustDB	CLSK749567.
Enzyme and pathway databases
BioCyc	ECHA205920:GJNR-843-MONOMER.
Family and domain databases
InterPro	IPR002575. Aminoglycoside_PTrfase. IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR010232. UbiB. IPR004147. UbiB_dom. [Graphical view]
Pfam	PF03109. ABC1. 1 hit. PF01636. APH. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
TIGRFAMs	TIGR01982. UbiB. 1 hit.
PROSITE	PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2GFZ7_EHRCR

Accession

Primary (citable) accession number: Q2GFZ7

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2006
Last sequence update:	March 21, 2006
Last modified:	May 29, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)