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Protein

Elongation factor Tu

Gene

tuf1

more
Organism
Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi15 – 22GTPUniRule annotation8
Nucleotide bindingi80 – 84GTPUniRule annotation5
Nucleotide bindingi135 – 138GTPUniRule annotation4

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tuf1UniRule annotation
Ordered Locus Names:ECH_0407
AND
Name:tuf2UniRule annotation
Ordered Locus Names:ECH_0960
OrganismiEhrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)
Taxonomic identifieri205920 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeEhrlichia
Proteomesi
  • UP000008320 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003373751 – 395Elongation factor TuAdd BLAST395

Proteomic databases

PRIDEiQ2GFN6.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi205920.ECH_0960.

Structurei

3D structure databases

ProteinModelPortaliQ2GFN6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 205tr-type GAdd BLAST200

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni15 – 22G1By similarity8
Regioni59 – 63G2By similarity5
Regioni80 – 83G3By similarity4
Regioni135 – 138G4By similarity4
Regioni173 – 175G5By similarity3

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CGV. Bacteria.
COG0050. LUCA.
HOGENOMiHOG000229290.
KOiK02358.
OMAiIEMFHKE.
OrthoDBiPOG091H00LA.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiIPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2GFN6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVEERKPHIN VGTIGHVDHG KTTLTAALTT VLAKRLSGEG NKSVKYDEID
60 70 80 90 100
KAPEEKARGI TISTAHVEYE TENRHYAHVD CPGHADYIKN MITGAAQMDA
110 120 130 140 150
AILVVSATDG AMPQTREHIL LAKQVGVKDI VVWMNKCDVV DDEEMLSLVE
160 170 180 190 200
MEIRELLSKY GYPGDDIDVV RGSAVKALEE ETGSGVWSEK IMELMNALEK
210 220 230 240 250
ISLPTREKDK PFLMSIEDVF SIPGRGTVVT GRIERGVIRV GDKIEIVGLR
260 270 280 290 300
DIQSTVCTGV EMFHKALDAG EAGDNAGILL RGIKKEDVER GQVLSAPGQI
310 320 330 340 350
HSYKKFKAEV YILKKEEGGR HTPFFSNYQP QFYVRTTDVT GSIKLPEGVE
360 370 380 390
MVMPGDNISI EVSLDKPVAI DKGLRFAIRE GGRTVGSGII TEILE
Length:395
Mass (Da):43,387
Last modified:March 21, 2006 - v1
Checksum:iED84EAF10C6F59F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000236 Genomic DNA. Translation: ABD45144.1.
CP000236 Genomic DNA. Translation: ABD45570.1.
RefSeqiWP_006011505.1. NC_007799.1.

Genome annotation databases

EnsemblBacteriaiABD45144; ABD45144; ECH_0407.
ABD45570; ABD45570; ECH_0960.
KEGGiech:ECH_0407.
ech:ECH_0960.
PATRICi20576291. VBIEhrCha103583_0344.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000236 Genomic DNA. Translation: ABD45144.1.
CP000236 Genomic DNA. Translation: ABD45570.1.
RefSeqiWP_006011505.1. NC_007799.1.

3D structure databases

ProteinModelPortaliQ2GFN6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi205920.ECH_0960.

Proteomic databases

PRIDEiQ2GFN6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD45144; ABD45144; ECH_0407.
ABD45570; ABD45570; ECH_0960.
KEGGiech:ECH_0407.
ech:ECH_0960.
PATRICi20576291. VBIEhrCha103583_0344.

Phylogenomic databases

eggNOGiENOG4105CGV. Bacteria.
COG0050. LUCA.
HOGENOMiHOG000229290.
KOiK02358.
OMAiIEMFHKE.
OrthoDBiPOG091H00LA.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiIPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiEFTU_EHRCR
AccessioniPrimary (citable) accession number: Q2GFN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 21, 2006
Last modified: November 2, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.