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Q2GFN6

- EFTU_EHRCR

UniProt

Q2GFN6 - EFTU_EHRCR

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Protein
Elongation factor Tu
Gene
tuf1, ECH_0407
tuf2, ECH_0960
Organism
Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 228GTP By similarity
Nucleotide bindingi80 – 845GTP By similarity
Nucleotide bindingi135 – 1384GTP By similarity

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciECHA205920:GJNR-408-MONOMER.
ECHA205920:GJNR-963-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor Tu
Short name:
EF-Tu
Gene namesi
Name:tuf1
Ordered Locus Names:ECH_0407
AND
Name:tuf2
Ordered Locus Names:ECH_0960
OrganismiEhrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)
Taxonomic identifieri205920 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeEhrlichia
ProteomesiUP000008320: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 395395Elongation factor TuUniRule annotation
PRO_0000337375Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi205920.ECH_0960.

Structurei

3D structure databases

ProteinModelPortaliQ2GFN6.
SMRiQ2GFN6. Positions 3-394.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 205200tr-type G
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni15 – 228G1 By similarity
Regioni59 – 635G2 By similarity
Regioni80 – 834G3 By similarity
Regioni135 – 1384G4 By similarity
Regioni173 – 1753G5 By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
KOiK02358.
OMAiERKPHIN.
OrthoDBiEOG6R5C6X.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2GFN6-1 [UniParc]FASTAAdd to Basket

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MVEERKPHIN VGTIGHVDHG KTTLTAALTT VLAKRLSGEG NKSVKYDEID    50
KAPEEKARGI TISTAHVEYE TENRHYAHVD CPGHADYIKN MITGAAQMDA 100
AILVVSATDG AMPQTREHIL LAKQVGVKDI VVWMNKCDVV DDEEMLSLVE 150
MEIRELLSKY GYPGDDIDVV RGSAVKALEE ETGSGVWSEK IMELMNALEK 200
ISLPTREKDK PFLMSIEDVF SIPGRGTVVT GRIERGVIRV GDKIEIVGLR 250
DIQSTVCTGV EMFHKALDAG EAGDNAGILL RGIKKEDVER GQVLSAPGQI 300
HSYKKFKAEV YILKKEEGGR HTPFFSNYQP QFYVRTTDVT GSIKLPEGVE 350
MVMPGDNISI EVSLDKPVAI DKGLRFAIRE GGRTVGSGII TEILE 395
Length:395
Mass (Da):43,387
Last modified:March 21, 2006 - v1
Checksum:iED84EAF10C6F59F7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000236 Genomic DNA. Translation: ABD45144.1.
CP000236 Genomic DNA. Translation: ABD45570.1.
RefSeqiYP_507225.1. NC_007799.1.
YP_507747.1. NC_007799.1.

Genome annotation databases

EnsemblBacteriaiABD45144; ABD45144; ECH_0407.
ABD45570; ABD45570; ECH_0960.
GeneIDi3927003.
3927878.
KEGGiech:ECH_0407.
ech:ECH_0960.
PATRICi20576291. VBIEhrCha103583_0344.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000236 Genomic DNA. Translation: ABD45144.1 .
CP000236 Genomic DNA. Translation: ABD45570.1 .
RefSeqi YP_507225.1. NC_007799.1.
YP_507747.1. NC_007799.1.

3D structure databases

ProteinModelPortali Q2GFN6.
SMRi Q2GFN6. Positions 3-394.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 205920.ECH_0960.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABD45144 ; ABD45144 ; ECH_0407 .
ABD45570 ; ABD45570 ; ECH_0960 .
GeneIDi 3927003.
3927878.
KEGGi ech:ECH_0407.
ech:ECH_0960.
PATRICi 20576291. VBIEhrCha103583_0344.

Phylogenomic databases

eggNOGi COG0050.
HOGENOMi HOG000229290.
KOi K02358.
OMAi ERKPHIN.
OrthoDBi EOG6R5C6X.

Enzyme and pathway databases

BioCyci ECHA205920:GJNR-408-MONOMER.
ECHA205920:GJNR-963-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC CRL-10679 / Arkansas.

Entry informationi

Entry nameiEFTU_EHRCR
AccessioniPrimary (citable) accession number: Q2GFN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 21, 2006
Last modified: September 3, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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