Q2GF85 (Q2GF85_EHRCR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dehydrogenase, isocitrate/isopropylmalate family EMBL ABD45001.1

Gene names

Ordered Locus Names:

ECH_1114

Organism

Ehrlichia chaffeensis (strain Arkansas) [Complete proteome] [HAMAP] EMBL ABD45001.1

Taxonomic identifier

205920 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Ehrlichia › canis group › Ehrlichia chaffeensis

Protein attributes

Sequence length	482 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004444
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glyoxylate cycle Inferred from electronic annotation. Source: InterPro tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	NAD binding Inferred from electronic annotation. Source: InterPro isocitrate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2GF85 [UniParc]. Last modified March 21, 2006. Version 1. Checksum: 32361B8B69B70C82	FASTA	482	54,138
	10 20 30 40 50 60 MSIPITVAYG DGIGPEIMEA VLLILSEAES GLVVETIEVG HNLYKKEWSS GIAPSSWDSI 70 80 90 100 110 120 YRTKVLLKSP TMTPQGRGHK SLNVTLRKRL GLYANIRPCI SYHPVIKTRY PNLNVVIVRE 130 140 150 160 170 180 NEEDTYTGIE HRLTNDTYQC SKVITRSGSE RICDYAFHYA KVHNRKRVTC LIKDNIMKMT 190 200 210 220 230 240 DGIFHKSFSK IAENYPDIES DHYIVDIGMA KVASNPENFD VIVTTNLYGD IVSDIVAELS 250 260 270 280 290 300 GSIGLAGSAN IGNNYAMFEA VHGSAPDIAG KNIANPSGLL NAAIQMLMYL KQFDKAQLIY 310 320 330 340 350 360 NAFLKTLEDG IHTADIYQSQ VSKKKVSTMD FAKAVVENFG QSPSQLPKSM FQDNVDRTGV 370 380 390 400 410 420 SYTYEPSYVT RVLVGVDITI GCDGVGLDFK QLINNLQNIT HDKLELVLIH NKGLEIWPDE 430 440 450 460 470 480 SVSVNLSYMD QVCCRFYMKS KDDKIMNEHI NQLLFDIEQK KIDVVKMEKL YLYNDQPGFF TM

References

[1]

"Comparative genomics of emerging human ehrlichiosis agents." Dunning Hotopp J.C., Lin M., Madupu R., Crabtree J., Angiuoli S.V., Eisen J.A., Seshadri R., Ren Q., Wu M., Utterback T.R., Smith S., Lewis M., Khouri H., Zhang C., Niu H., Lin Q., Ohashi N., Zhi N. , Nelson W.C., Brinkac L.M., Dodson R.J., Rosovitz M.J., Sundaram J.P., Daugherty S.C., Davidsen T., Durkin A.S., Gwinn M.L., Haft D.H., Selengut J.D., Sullivan S.A., Zafar N., Zhou L., Benahmed F., Forberger H., Halpin R., Mulligan S., Robinson J., White O., Rikihisa Y., Tettelin H. PLoS Genet. 2:208-222(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Arkansas.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000236 Genomic DNA. Translation: ABD45001.1.
RefSeq	YP_507898.1. NC_007799.1.
3D structure databases
ProteinModelPortal	Q2GF85.
ModBase	Search...
Protein-protein interaction databases
STRING	205920.ECH_1114.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABD45001; ABD45001; ECH_1114.
GeneID	3927888.
KEGG	ech:ECH_1114.
PATRIC	20577560. VBIEhrCha103583_0954.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0473.
HOGENOM	HOG000021113.
KO	K00031.
OMA	SGSERIC.
ProtClustDB	PRK09222.
Enzyme and pathway databases
BioCyc	ECHA205920:GJNR-1117-MONOMER.
Family and domain databases
Gene3D	3.40.718.10. 1 hit.
InterPro	IPR019818. IsoCit/isopropylmalate_DH_CS. IPR001804. Isocitrate/isopropylmalate_DH. IPR014273. Isocitrate_DH_aproteobac-typ. IPR024084. IsoPropMal-DH-like_dom. [Graphical view]
PANTHER	PTHR11835. PTHR11835. 1 hit.
Pfam	PF00180. Iso_dh. 1 hit. [Graphical view]
TIGRFAMs	TIGR02924. ICDH_alpha. 1 hit.
PROSITE	PS00470. IDH_IMDH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2GF85_EHRCR

Accession

Primary (citable) accession number: Q2GF85

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2006
Last sequence update:	March 21, 2006
Last modified:	May 1, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)