Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Dehydrogenase, isocitrate/isopropylmalate family

Gene

ECH_1114

Organism
Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: InterPro
  2. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Enzyme and pathway databases

BioCyciECHA205920:GJNR-1117-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Dehydrogenase, isocitrate/isopropylmalate familyImported
Gene namesi
Ordered Locus Names:ECH_1114Imported
OrganismiEhrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)Imported
Taxonomic identifieri205920 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeEhrlichia
ProteomesiUP000008320: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi205920.ECH_1114.

Structurei

3D structure databases

ProteinModelPortaliQ2GF85.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0473.
HOGENOMiHOG000021113.
KOiK00031.
OMAiLRPCKTY.
OrthoDBiEOG65XN31.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2GF85-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIPITVAYG DGIGPEIMEA VLLILSEAES GLVVETIEVG HNLYKKEWSS
60 70 80 90 100
GIAPSSWDSI YRTKVLLKSP TMTPQGRGHK SLNVTLRKRL GLYANIRPCI
110 120 130 140 150
SYHPVIKTRY PNLNVVIVRE NEEDTYTGIE HRLTNDTYQC SKVITRSGSE
160 170 180 190 200
RICDYAFHYA KVHNRKRVTC LIKDNIMKMT DGIFHKSFSK IAENYPDIES
210 220 230 240 250
DHYIVDIGMA KVASNPENFD VIVTTNLYGD IVSDIVAELS GSIGLAGSAN
260 270 280 290 300
IGNNYAMFEA VHGSAPDIAG KNIANPSGLL NAAIQMLMYL KQFDKAQLIY
310 320 330 340 350
NAFLKTLEDG IHTADIYQSQ VSKKKVSTMD FAKAVVENFG QSPSQLPKSM
360 370 380 390 400
FQDNVDRTGV SYTYEPSYVT RVLVGVDITI GCDGVGLDFK QLINNLQNIT
410 420 430 440 450
HDKLELVLIH NKGLEIWPDE SVSVNLSYMD QVCCRFYMKS KDDKIMNEHI
460 470 480
NQLLFDIEQK KIDVVKMEKL YLYNDQPGFF TM
Length:482
Mass (Da):54,138
Last modified:March 21, 2006 - v1
Checksum:i32361B8B69B70C82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000236 Genomic DNA. Translation: ABD45001.1.
RefSeqiWP_006011301.1. NC_007799.1.
YP_507898.1. NC_007799.1.

Genome annotation databases

EnsemblBacteriaiABD45001; ABD45001; ECH_1114.
GeneIDi3927888.
KEGGiech:ECH_1114.
PATRICi20577560. VBIEhrCha103583_0954.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000236 Genomic DNA. Translation: ABD45001.1.
RefSeqiWP_006011301.1. NC_007799.1.
YP_507898.1. NC_007799.1.

3D structure databases

ProteinModelPortaliQ2GF85.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi205920.ECH_1114.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD45001; ABD45001; ECH_1114.
GeneIDi3927888.
KEGGiech:ECH_1114.
PATRICi20577560. VBIEhrCha103583_0954.

Phylogenomic databases

eggNOGiCOG0473.
HOGENOMiHOG000021113.
KOiK00031.
OMAiLRPCKTY.
OrthoDBiEOG65XN31.

Enzyme and pathway databases

BioCyciECHA205920:GJNR-1117-MONOMER.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC CRL-10679 / ArkansasImported.

Entry informationi

Entry nameiQ2GF85_EHRCR
AccessioniPrimary (citable) accession number: Q2GF85
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: March 4, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.