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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei142GTPUniRule annotation1
Binding sitei146GTPUniRule annotation1
Binding sitei190GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 28GTPUniRule annotation5
Nucleotide bindingi111 – 113GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciECHA205920:G1G5L-949-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:ECH_1153Imported
OrganismiEhrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)Imported
Taxonomic identifieri205920 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeEhrlichia
Proteomesi
  • UP000008320 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi205920.ECH_1153

Structurei

3D structure databases

ProteinModelPortaliQ2GF46
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 208TubulinInterPro annotationAdd BLAST193
Domaini210 – 328Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiIMNQGGV
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q2GF46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLNICLPDQ SLLRPRITVF GVGGAGGNAV NNMIQSNLHG VNFVVANTDA
60 70 80 90 100
QALELSLSEK KIQLGIGLTK GLGAGSLPEV GRGAAEESIN EIIEEISDSN
110 120 130 140 150
MLFITAGMGG GTGTGAAPVI ARVAKENKIL TIGVVTKPFH FEGAHRMRTA
160 170 180 190 200
EFGLEELQRY VDTLIVIPNQ NLFRIANEKT TFADAFKLAD TVLHTGVRGI
210 220 230 240 250
TDLMVMPGLI NLDFADIRAI MSEMGKAMMG TGEAEGENRA IAAAEAAISN
260 270 280 290 300
PLLDNISMKG AKGILINITG GLDMTLFEVD AAANRIREEV DSHANIIFGS
310 320 330 340 350
TFNKESEGKI RVSVLATGID NEEVVIQNKS ALKDKEAHND KLSETSSKPF
360 370 380 390 400
NPLDNEIAYY KPSNPGEDMI HSINHTKKQD HNIENQKSNN KIPESAYKMQ
410 420
FNKNEYWDEE SFNIPTFLRK K
Length:421
Mass (Da):45,687
Last modified:March 21, 2006 - v1
Checksum:iE73CE027880B75FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000236 Genomic DNA Translation: ABD45501.1
RefSeqiWP_011453045.1, NC_007799.1

Genome annotation databases

EnsemblBacteriaiABD45501; ABD45501; ECH_1153
KEGGiech:ECH_1153

Similar proteinsi

Entry informationi

Entry nameiQ2GF46_EHRCR
AccessioniPrimary (citable) accession number: Q2GF46
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: March 28, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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