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Q2GEZ6 (SYR_NEOSM) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:NSE_0049
OrganismNeorickettsia sennetsu (strain Miyayama) [Complete proteome] [HAMAP]
Taxonomic identifier222891 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeNeorickettsia

Protein attributes

Sequence length570 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 570570Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242054

Regions

Motif127 – 13711"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q2GEZ6 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: C34A9D601631AEA0

FASTA57064,103
        10         20         30         40         50         60 
MDLFLRLGNV LTEVVTSIFG VTLSEQVLLW NSPKKREYGD FSTAISFLIA KEVRLSLHEV 

        70         80         90        100        110        120 
ACSIADGLRS FKDLFKNVSV ASGGFINVFL TSDTWSEFLA AVSDDAGGYG FSDIGHAVPL 

       130        140        150        160        170        180 
NLEFVSANPT GPLHLGHIRG AVLFDIFAEL LDKFGFSLTR EYYINDAGKQ IDLLVYSVFV 

       190        200        210        220        230        240 
RFCEQLRKKE SDNFPSNCYA GDYIRDIASY LISTFPDSVK DTTELKSFSD TFREVILSLT 

       250        260        270        280        290        300 
MDMIKSDLAK LGISYDCYVR EKELHEGNYI EKVIAVLDEK GYLDEEELPS PKGKSGDWVE 

       310        320        330        340        350        360 
RRQKVFLSTK FGDDTNRALQ KVDGSWTYFA SDVAYHYHKL ERGFNHMIVG LGADHAGYVK 

       370        380        390        400        410        420 
RLSGVVEALS GGDARIDIKL YNLVNLFRNG KPVKLSKRNG DLITLDDVLE SGITVSEIRF 

       430        440        450        460        470        480 
AMLTKSSEIV LDFDLDKFVR ASYDNPLFYV QYAHARCSSL LRKRGPSAKC DAAMLVEKQE 

       490        500        510        520        530        540 
LDLMVTLAKL PSLLKVIVVS GEVHKLTFYL HEVAERFHAL WNAGMIENKF RFIIEDEPEL 

       550        560        570 
TNARLILVKA VKNTLASVLK VMKIEPAERM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000237 Genomic DNA. Translation: ABD45830.1.
RefSeqYP_505950.1. NC_007798.1.

3D structure databases

ProteinModelPortalQ2GEZ6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING222891.NSE_0049.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABD45830; ABD45830; NSE_0049.
GeneID3931760.
KEGGnse:NSE_0049.
PATRIC22680213. VBINeoSen119815_0050.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAIRNTIND.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycNSEN222891:GHFU-50-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_NEOSM
AccessionPrimary (citable) accession number: Q2GEZ6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: March 21, 2006
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries