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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Neorickettsia sennetsu (strain ATCC VR-367 / Miyayama) (Ehrlichia sennetsu)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciNSEN222891:G1G5M-41-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:NSE_0049
OrganismiNeorickettsia sennetsu (strain ATCC VR-367 / Miyayama) (Ehrlichia sennetsu)
Taxonomic identifieri222891 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeNeorickettsia
Proteomesi
  • UP000001942 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420541 – 570Arginine--tRNA ligaseAdd BLAST570

Proteomic databases

PRIDEiQ2GEZ6

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi222891.NSE_0049

Structurei

3D structure databases

ProteinModelPortaliQ2GEZ6
SMRiQ2GEZ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi127 – 137"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q2GEZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLFLRLGNV LTEVVTSIFG VTLSEQVLLW NSPKKREYGD FSTAISFLIA
60 70 80 90 100
KEVRLSLHEV ACSIADGLRS FKDLFKNVSV ASGGFINVFL TSDTWSEFLA
110 120 130 140 150
AVSDDAGGYG FSDIGHAVPL NLEFVSANPT GPLHLGHIRG AVLFDIFAEL
160 170 180 190 200
LDKFGFSLTR EYYINDAGKQ IDLLVYSVFV RFCEQLRKKE SDNFPSNCYA
210 220 230 240 250
GDYIRDIASY LISTFPDSVK DTTELKSFSD TFREVILSLT MDMIKSDLAK
260 270 280 290 300
LGISYDCYVR EKELHEGNYI EKVIAVLDEK GYLDEEELPS PKGKSGDWVE
310 320 330 340 350
RRQKVFLSTK FGDDTNRALQ KVDGSWTYFA SDVAYHYHKL ERGFNHMIVG
360 370 380 390 400
LGADHAGYVK RLSGVVEALS GGDARIDIKL YNLVNLFRNG KPVKLSKRNG
410 420 430 440 450
DLITLDDVLE SGITVSEIRF AMLTKSSEIV LDFDLDKFVR ASYDNPLFYV
460 470 480 490 500
QYAHARCSSL LRKRGPSAKC DAAMLVEKQE LDLMVTLAKL PSLLKVIVVS
510 520 530 540 550
GEVHKLTFYL HEVAERFHAL WNAGMIENKF RFIIEDEPEL TNARLILVKA
560 570
VKNTLASVLK VMKIEPAERM
Length:570
Mass (Da):64,103
Last modified:March 21, 2006 - v1
Checksum:iC34A9D601631AEA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000237 Genomic DNA Translation: ABD45830.1
RefSeqiWP_011451456.1, NC_007798.1

Genome annotation databases

EnsemblBacteriaiABD45830; ABD45830; NSE_0049
KEGGinse:NSE_0049

Similar proteinsi

Entry informationi

Entry nameiSYR_NEOSM
AccessioniPrimary (citable) accession number: Q2GEZ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: March 21, 2006
Last modified: May 23, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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