Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q2GDY1

- NUOA_NEOSM

UniProt

Q2GDY1 - NUOA_NEOSM

Protein

NADH-quinone oxidoreductase subunit A

Gene

nuoA

Organism
Neorickettsia sennetsu (strain Miyayama)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
  1. Functioni

    NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.UniRule annotation

    Catalytic activityi

    NADH + quinone = NAD+ + quinol.UniRule annotation

    GO - Molecular functioni

    1. NADH dehydrogenase (quinone) activity Source: TIGR
    2. NADH dehydrogenase (ubiquinone) activity Source: InterPro
    3. quinone binding Source: UniProtKB-KW

    GO - Biological processi

    1. transport Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    NAD, Ubiquinone

    Enzyme and pathway databases

    BioCyciNSEN222891:GHFU-430-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    NADH-quinone oxidoreductase subunit AUniRule annotation (EC:1.6.99.5UniRule annotation)
    Alternative name(s):
    NADH dehydrogenase I subunit AUniRule annotation
    NDH-1 subunit AUniRule annotation
    NUO1UniRule annotation
    Gene namesi
    Name:nuoAUniRule annotation
    Ordered Locus Names:NSE_0429
    OrganismiNeorickettsia sennetsu (strain Miyayama)
    Taxonomic identifieri222891 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeNeorickettsia
    ProteomesiUP000001942: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 130130NADH-quinone oxidoreductase subunit APRO_0000362705Add
    BLAST

    Keywords - PTMi

    Quinone

    Interactioni

    Subunit structurei

    NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.UniRule annotation

    Protein-protein interaction databases

    STRINGi222891.NSE_0429.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei17 – 3721HelicalUniRule annotationAdd
    BLAST
    Transmembranei74 – 9421HelicalUniRule annotationAdd
    BLAST
    Transmembranei99 – 11921HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the complex I subunit 3 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0838.
    HOGENOMiHOG000100119.
    KOiK00330.
    OrthoDBiEOG6QVRQ6.

    Family and domain databases

    HAMAPiMF_01394. NDH1_NuoA.
    InterProiIPR023043. NAD(P)H_OxRDtase_bac/plastid.
    IPR000440. NADH_UbQ/plastoQ_OxRdtase_su3.
    [Graphical view]
    PANTHERiPTHR11058. PTHR11058. 1 hit.
    PfamiPF00507. Oxidored_q4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2GDY1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLESSVVGIG KWVVEDYIFV GLFFVVACFI SCVMLALPVF IAPSSHERHK    50
    GDSYECGFDK LSSTGERFNV RFYLVGILFI IFDLEIIFLF PWAVSARELG 100
    PAAFVSVLIF LIILTVGFVY EFVSGALDWR 130
    Length:130
    Mass (Da):14,633
    Last modified:February 10, 2009 - v2
    Checksum:iB3835B3675DC6972
    GO

    Sequence cautioni

    The sequence ABD45956.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000237 Genomic DNA. Translation: ABD45956.1. Different initiation.
    RefSeqiYP_506315.1. NC_007798.1.

    Genome annotation databases

    EnsemblBacteriaiABD45956; ABD45956; NSE_0429.
    GeneIDi3932227.
    KEGGinse:NSE_0429.
    PATRICi22680913. VBINeoSen119815_0385.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000237 Genomic DNA. Translation: ABD45956.1 . Different initiation.
    RefSeqi YP_506315.1. NC_007798.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 222891.NSE_0429.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABD45956 ; ABD45956 ; NSE_0429 .
    GeneIDi 3932227.
    KEGGi nse:NSE_0429.
    PATRICi 22680913. VBINeoSen119815_0385.

    Phylogenomic databases

    eggNOGi COG0838.
    HOGENOMi HOG000100119.
    KOi K00330.
    OrthoDBi EOG6QVRQ6.

    Enzyme and pathway databases

    BioCyci NSEN222891:GHFU-430-MONOMER.

    Family and domain databases

    HAMAPi MF_01394. NDH1_NuoA.
    InterProi IPR023043. NAD(P)H_OxRDtase_bac/plastid.
    IPR000440. NADH_UbQ/plastoQ_OxRdtase_su3.
    [Graphical view ]
    PANTHERi PTHR11058. PTHR11058. 1 hit.
    Pfami PF00507. Oxidored_q4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Miyayama.

    Entry informationi

    Entry nameiNUOA_NEOSM
    AccessioniPrimary (citable) accession number: Q2GDY1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 10, 2009
    Last sequence update: February 10, 2009
    Last modified: October 1, 2014
    This is version 57 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3