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Q2GC39 (RSMG_NOVAD) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase G

EC=2.1.1.170
Alternative name(s):
16S rRNA 7-methylguanosine methyltransferase
Short name=16S rRNA m7G methyltransferase
Gene names
Name:rsmG
Ordered Locus Names:Saro_0135
OrganismNovosphingobium aromaticivorans (strain DSM 12444) [Complete proteome] [HAMAP]
Taxonomic identifier279238 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeNovosphingobium

Protein attributes

Sequence length230 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the N7 position of guanine in position 527 of 16S rRNA By similarity. HAMAP-Rule MF_00074

Catalytic activity

S-adenosyl-L-methionine + guanine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(527) in 16S rRNA. HAMAP-Rule MF_00074

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00074.

Sequence similarities

Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionrRNA (guanine-N7-)-methyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 230230Ribosomal RNA small subunit methyltransferase G HAMAP-Rule MF_00074
PRO_0000335387

Regions

Region131 – 1322S-adenosyl-L-methionine binding By similarity

Sites

Binding site801S-adenosyl-L-methionine; via carbonyl oxygen By similarity
Binding site851S-adenosyl-L-methionine; via carbonyl oxygen By similarity
Binding site1451S-adenosyl-L-methionine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2GC39 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: E226713AF1608F88

FASTA23025,305
        10         20         30         40         50         60 
MTLVTEVEAQ AWLREVLHVD DASMSRLAHL VDLLLAENER QNLVARGTLP HVWVRHIVDS 

        70         80         90        100        110        120 
AQLLHVSRET SGSGEWLDLG TGAGFPGLVI AAIQSDRPVT LVDSRRLRTE WLQRAADALE 

       130        140        150        160        170        180 
LSNVRVILSR VEDLESGAYA AISARAFAPL DKLLAISARF STPDTLWLLP KGAGAQHELQ 

       190        200        210        220        230 
MLPESWHHMF HVEQSLTDPA AGIIVGRLLA GKQPAPHVSR QQAPRKGKRT 

« Hide

References

[1]"Complete sequence of Novosphingobium aromaticivorans DSM 12444."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N. expand/collapse author list , Fredrickson J., Balkwill D., Romine M.F., Richardson P.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 12444.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000248 Genomic DNA. Translation: ABD24584.1.
RefSeqYP_495418.1. NC_007794.1.

3D structure databases

ProteinModelPortalQ2GC39.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING279238.Saro_0135.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABD24584; ABD24584; Saro_0135.
GeneID3916021.
KEGGnar:Saro_0135.
PATRIC22782848. VBINovAro50627_0141.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0357.
HOGENOMHOG000221015.
KOK03501.
OMAHNERAEN.
OrthoDBEOG6HF639.
ProtClustDBCLSK844134.

Enzyme and pathway databases

BioCycNARO279238:GHBU-135-MONOMER.

Family and domain databases

HAMAPMF_00074. 16SrRNA_methyltr_G.
InterProIPR003682. rRNA_ssu_MeTfrase_G.
[Graphical view]
PfamPF02527. GidB. 1 hit.
[Graphical view]
PIRSFPIRSF003078. GidB. 1 hit.
TIGRFAMsTIGR00138. gidB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRSMG_NOVAD
AccessionPrimary (citable) accession number: Q2GC39
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 21, 2006
Last modified: April 16, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families