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Reviewed, UniProtKB/Swiss-Prot Q2GAB9 (XYLA_NOVAD)

Last modified June 16, 2009. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Xylose isomerase
    EC=5.3.1.5
Gene names
Name: xylA
Ordered Locus Names: Saro_0757
OrganismNovosphingobium aromaticivorans (strain DSM 12444) [Complete proteome] [HAMAP]
Taxonomic identifier279238 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Novosphingobium

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Protein attributes

Sequence length437 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the xylose isomerase family.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 437437Xylose isomerase HAMAP MF_00455
PRO_0000236965

Sites

Active site1021 By similarity
Active site1051 By similarity
Metal binding2331Magnesium 1 By similarity
Metal binding2691Magnesium 1 By similarity
Metal binding2691Magnesium 2 By similarity
Metal binding2721Magnesium 2 By similarity
Metal binding2971Magnesium 1 By similarity
Metal binding3081Magnesium 2 By similarity
Metal binding3101Magnesium 2 By similarity
Metal binding3401Magnesium 1 By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q2GAB9-1 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: 68C4F2157114A246

FASTA43748,845
        10         20         30         40         50         60 
MSADYFADFQ TVRYEGPDSD NDFAYRWYDK DRVILGKRME DHLRFAVCMW HTFCWPGSDV 

        70         80         90        100        110        120 
FGAGTFTRPW LQGPMDARNA AAKREAALAF VEKLDVPFYC FHDVDVMAEA EGIGEFRSSF 

       130        140        150        160        170        180 
AEAVDHLEEL QGKHGRKLLW GTANLFGHPR YMAGAATNPD PEVFAWGASQ VRDALEATHR 

       190        200        210        220        230        240 
LGGANYVLWG GREGYDSILN TEIGIEQENF GRFLSLVVDH KHRIGFKGTI LIEPKPHEPT 

       250        260        270        280        290        300 
KHQYDFDTQT VFGFLKRFGL ESEVKVNIEA NHATLSGHTF EHELAMARAL GILGSIDANR 

       310        320        330        340        350        360 
GDHQNGWDTD QFPNSVEELT LAMLELIRAG GFTDGGFNFD AKVRRQSIDA ADLFHGHIGG 

       370        380        390        400        410        420 
IDTIAHALVK AAALIEDGKL DAFRAERYAG WQGELGRKIH ADGTTLADIA DIAVARDLAP 

       430 
VRRSGRQEWC ENLINRV

« Hide

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References

[1]"Complete sequence of Novosphingobium aromaticivorans DSM 12444."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N. expand/collapse author list , Fredrickson J., Balkwill D., Romine M.F., Richardson P.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000248 Genomic DNA. Translation: ABD25204.1.
RefSeqYP_496038.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3918581.
GenomeReviewsGene locus Saro_0757 in contig CP000248_GR.
KEGGnar:Saro_0757.
NMPDRfig|48935.1.peg.1772.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ2GAB9.
OMAQ2GAB9. QFLIEPK.

Enzyme and pathway databases

BioCycNARO279238:SARO_0757-MON.

Family and domain databases

HAMAPMF_00455.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase-typ_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
IPR018115. Xylose_isomerase_AS.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameXYLA_NOVAD
AccessionPrimary (citable) accession number: Q2GAB9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: March 21, 2006
Last modified: June 16, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents