ID   Q2GA33_NOVAD            Unreviewed;       429 AA.
AC   Q2GA33;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 80.
DE   SubName: Full=Metal dependent phosphohydrolase {ECO:0000313|EMBL:ABD25290.1};
GN   OrderedLocusNames=Saro_0845 {ECO:0000313|EMBL:ABD25290.1};
OS   Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG
OS   56034 / CIP 105152 / NBRC 16084 / F199).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Novosphingobium.
OX   NCBI_TaxID=279238 {ECO:0000313|EMBL:ABD25290.1, ECO:0000313|Proteomes:UP000009134};
RN   [1] {ECO:0000313|Proteomes:UP000009134}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084
RC   / F199 {ECO:0000313|Proteomes:UP000009134};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N.,
RA   Fredrickson J., Balkwill D., Romine M.F., Richardson P.;
RT   "Complete sequence of Novosphingobium aromaticivorans DSM 12444.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP000248; ABD25290.1; -; Genomic_DNA.
DR   RefSeq; WP_011444504.1; NC_007794.1.
DR   AlphaFoldDB; Q2GA33; -.
DR   STRING; 279238.Saro_0845; -.
DR   KEGG; nar:Saro_0845; -.
DR   eggNOG; COG2206; Bacteria.
DR   HOGENOM; CLU_000445_92_1_5; -.
DR   Proteomes; UP000009134; Chromosome.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:UniProt.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR021812; DUF3391.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR   PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR   Pfam; PF11871; DUF3391; 1.
DR   Pfam; PF13487; HD_5; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   PROSITE; PS51832; HD_GYP; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ABD25290.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009134}.
FT   DOMAIN          156..351
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
SQ   SEQUENCE   429 AA;  46923 MW;  BADFEC46043AB5F0 CRC64;
     MLKRISTDDI ELGMFIHKLE GSWFRHPFWK SRFLLEDQEL LDTLRGSGIE GVVIDTGRGK
     DTTEPVETEA STRLRTPARL AVEARIPERR AVAPVVTQHA VFARAAPALQ IAREFGRARR
     AAGDAMRVVS RTFIEARLGK AVTAHEVEPV LDAIYSSVQR NLYAFNGLLR CQSDSEPVYR
     HSLAVSALMI ALARHMKFSP VDIRDAGMAG LLMDIGVGQL PVDLASVGGD YTRLRPDLKQ
     QHVLLGYSFL KAAGDIPEAV LRTVLHHHER LDASGYPQGL GGNAIDRLSR MAAICDAYDT
     VISGGDVASR VDPAEAIVLL REQPGKFDAA ILEKFVETVG VYPIGSFVRL RSDRLAMVVD
     EDPADAARPA VRTFWSVPLN KRLKGETIAL AHCYGEDSIE GIADLSGLDL PEVSRLRETL
     LAAACKDTA
//