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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei337Proton donorUniRule annotation1
Active sitei368UniRule annotation1
Active sitei478UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciNARO279238:G1G5T-1829-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Saro_1809
OrganismiNovosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199)
Taxonomic identifieri279238 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeNovosphingobium
Proteomesi
  • UP000009134 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002526321 – 507Glucose-6-phosphate isomeraseAdd BLAST507

Interactioni

Protein-protein interaction databases

STRINGi279238.Saro_1809

Structurei

3D structure databases

ProteinModelPortaliQ2G7C4
SMRiQ2G7C4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q2G7C4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVAEAETYW TALAGLPRPT LKELFSDAGR LDRYAATLDL PGGPIRFDWS
60 70 80 90 100
KTHLSAEVEA VFAALASAMD FEGRRAALIE GAKINNTEGR AAEHTAQRGI
110 120 130 140 150
GNEASVEEAE ALHARMRMLV DAIHAGALGE VRSLIHIGIG GSALGPALAI
160 170 180 190 200
DALTRDGAKV AVHVVSNIDG CALEAAMKAC DPATTMIAVA SKTFTTTETM
210 220 230 240 250
TNAASALEWL RENGVADPYG QVVALTAAPE KAVEWGVDET RVLPFSETVG
260 270 280 290 300
GRYSLWSSIG FPVAMALGWE GFAAFLDGAA AIDRHFIDAD LAGNVVVRAA
310 320 330 340 350
FADLYYTQVR GCQTRAVFAY DERLALLPDY LQQLEMESNG KRVLADGSPL
360 370 380 390 400
TRPSAPVTWG GVGTDAQHAV FQLLHQGTHL IPVDFLAVKT QGHDLDPAHH
410 420 430 440 450
QILLSNCFAQ GAALMAGKAS DDGARAYPGD RPSATILCDD LNPATLGALI
460 470 480 490 500
AFHEHRTFVS AVMLGINPFD QFGVELGKAI AKQIESGGGE GFDPSTEALL

AAVGLAG
Length:507
Mass (Da):53,414
Last modified:March 21, 2006 - v1
Checksum:iF9DFF60CDE1C7A18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000248 Genomic DNA Translation: ABD26249.1
RefSeqiWP_011445459.1, NC_007794.1

Genome annotation databases

EnsemblBacteriaiABD26249; ABD26249; Saro_1809
KEGGinar:Saro_1809

Similar proteinsi

Entry informationi

Entry nameiG6PI_NOVAD
AccessioniPrimary (citable) accession number: Q2G7C4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: March 21, 2006
Last modified: February 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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