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Q2G7C4 (G6PI_NOVAD) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:Saro_1809
OrganismNovosphingobium aromaticivorans (strain DSM 12444) [Complete proteome] [HAMAP]
Taxonomic identifier279238 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeNovosphingobium

Protein attributes

Sequence length507 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 507507Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000252632

Sites

Active site3371Proton donor By similarity
Active site3681 By similarity
Active site4781 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2G7C4 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: F9DFF60CDE1C7A18

FASTA50753,414
        10         20         30         40         50         60 
MTVAEAETYW TALAGLPRPT LKELFSDAGR LDRYAATLDL PGGPIRFDWS KTHLSAEVEA 

        70         80         90        100        110        120 
VFAALASAMD FEGRRAALIE GAKINNTEGR AAEHTAQRGI GNEASVEEAE ALHARMRMLV 

       130        140        150        160        170        180 
DAIHAGALGE VRSLIHIGIG GSALGPALAI DALTRDGAKV AVHVVSNIDG CALEAAMKAC 

       190        200        210        220        230        240 
DPATTMIAVA SKTFTTTETM TNAASALEWL RENGVADPYG QVVALTAAPE KAVEWGVDET 

       250        260        270        280        290        300 
RVLPFSETVG GRYSLWSSIG FPVAMALGWE GFAAFLDGAA AIDRHFIDAD LAGNVVVRAA 

       310        320        330        340        350        360 
FADLYYTQVR GCQTRAVFAY DERLALLPDY LQQLEMESNG KRVLADGSPL TRPSAPVTWG 

       370        380        390        400        410        420 
GVGTDAQHAV FQLLHQGTHL IPVDFLAVKT QGHDLDPAHH QILLSNCFAQ GAALMAGKAS 

       430        440        450        460        470        480 
DDGARAYPGD RPSATILCDD LNPATLGALI AFHEHRTFVS AVMLGINPFD QFGVELGKAI 

       490        500 
AKQIESGGGE GFDPSTEALL AAVGLAG 

« Hide

References

[1]"Complete sequence of Novosphingobium aromaticivorans DSM 12444."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N. expand/collapse author list , Fredrickson J., Balkwill D., Romine M.F., Richardson P.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 12444.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000248 Genomic DNA. Translation: ABD26249.1.
RefSeqYP_497083.1. NC_007794.1.

3D structure databases

ProteinModelPortalQ2G7C4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING279238.Saro_1809.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABD26249; ABD26249; Saro_1809.
GeneID3918368.
KEGGnar:Saro_1809.
PATRIC22786306. VBINovAro50627_1848.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMARLKYFAA.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycNARO279238:GHBU-1834-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_NOVAD
AccessionPrimary (citable) accession number: Q2G7C4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: March 21, 2006
Last modified: February 19, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways