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Protein

Putative fluoride ion transporter CrcB

Gene

crcB

Organism
Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Important for reducing fluoride concentration in the cell, thus reducing its toxicity.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Putative fluoride ion transporter CrcBUniRule annotation
Gene namesi
Name:crcBUniRule annotation
Ordered Locus Names:Saro_2836
OrganismiNovosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199)
Taxonomic identifieri279238 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeNovosphingobium
Proteomesi
  • UP000009134 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1 – 21HelicalUniRule annotationAdd BLAST21
Transmembranei33 – 53HelicalUniRule annotationAdd BLAST21
Transmembranei72 – 92HelicalUniRule annotationAdd BLAST21
Transmembranei97 – 117HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002529061 – 126Putative fluoride ion transporter CrcBAdd BLAST126

Interactioni

Protein-protein interaction databases

STRINGi279238.Saro_2836.

Family & Domainsi

Sequence similaritiesi

Belongs to the CrcB (TC 9.B.71) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG41082CG. Bacteria.
COG0239. LUCA.
HOGENOMiHOG000052573.
KOiK06199.
OMAiFGAMARY.
OrthoDBiPOG091H017F.

Family and domain databases

HAMAPiMF_00454. CrcB. 1 hit.
InterProiIPR003691. CrcB.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00494. crcB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2G4F1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTATAFVAIG GGIGAVLRFH AGRLATAIAG PNAVFPWGTF AINVVGSLLM
60 70 80 90 100
GVLAGWLARS GGGESLRLML GVGVLGGFTT FSAFSLETAL LVQRGTIGLA
110 120
ALYAAGSVVA GVTGLFLGLS IMRGVA
Length:126
Mass (Da):12,454
Last modified:October 17, 2006 - v2
Checksum:i4BD28D6A0AB95EEA
GO

Sequence cautioni

The sequence ABD27272 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000248 Genomic DNA. Translation: ABD27272.1. Different initiation.

Genome annotation databases

EnsemblBacteriaiABD27272; ABD27272; Saro_2836.
KEGGinar:Saro_2836.
PATRICi22788492. VBINovAro50627_2903.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000248 Genomic DNA. Translation: ABD27272.1. Different initiation.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi279238.Saro_2836.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD27272; ABD27272; Saro_2836.
KEGGinar:Saro_2836.
PATRICi22788492. VBINovAro50627_2903.

Phylogenomic databases

eggNOGiENOG41082CG. Bacteria.
COG0239. LUCA.
HOGENOMiHOG000052573.
KOiK06199.
OMAiFGAMARY.
OrthoDBiPOG091H017F.

Family and domain databases

HAMAPiMF_00454. CrcB. 1 hit.
InterProiIPR003691. CrcB.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00494. crcB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCRCB_NOVAD
AccessioniPrimary (citable) accession number: Q2G4F1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: October 17, 2006
Last modified: November 2, 2016
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.