Q2G3P3 (Q2G3P3_NOVAD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP-Rule MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP-Rule MF_01401
EC=1.8.4.11 HAMAP-Rule MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP-Rule MF_01401

Gene names

Name:	msrA HAMAP-Rule MF_01401
Ordered Locus Names:	Saro_3095 EMBL ABD27530.1

Organism

Novosphingobium aromaticivorans (strain DSM 12444) [Complete proteome] [HAMAP] EMBL ABD27530.1

Taxonomic identifier

279238 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Novosphingobium › Sphingomonas aromaticivorans

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP-Rule MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP-Rule MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP-Rule MF_01401 SAAS SAAS002569 EMBL ABD27530.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cellular protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular_function	peptide-methionine (S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	13	1	By similarity HAMAP-Rule MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q2G3P3 [UniParc]. Last modified March 21, 2006. Version 1. Checksum: 23E4303151466F74	FASTA	178	19,690
	10 20 30 40 50 60 MSEQATAILA GGCFWCTEAV FRDVIGVSNV ESGYIGGTVE SPTYKQVCSG STGHAEAIRV 70 80 90 100 110 120 TFDPQVIGYG QILDIFFATH DPTQLNRQGN DIGTQYRSAL FPLDDEQRSE AKAAIGRAQP 130 140 150 160 170 DWPRPIVTTI EGPATWYPAE DYHQEYWEGE GQRNPYCLAV IPPKLMKLRK SFANKVKA

References

[1]

"Complete sequence of Novosphingobium aromaticivorans DSM 12444." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N. , Fredrickson J., Balkwill D., Romine M.F., Richardson P. Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 12444.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000248 Genomic DNA. Translation: ABD27530.1.
RefSeq	YP_498364.1. NC_007794.1.
3D structure databases
ProteinModelPortal	Q2G3P3.
ModBase	Search...
Protein-protein interaction databases
STRING	279238.Saro_3095.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABD27530; ABD27530; Saro_3095.
GeneID	3918137.
KEGG	nar:Saro_3095.
PATRIC	22789042. VBINovAro50627_3173.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
HOGENOM	HOG000263863.
KO	K07304.
OMA	YCLAVIP.
ProtClustDB	CLSK844902.
Enzyme and pathway databases
BioCyc	NARO279238:GHBU-3787-MONOMER.
Family and domain databases
Gene3D	3.30.1060.10. 1 hit.
HAMAP	MF_01401. MsrA.
InterPro	IPR002569. Met_Sox_Rdtase_MsrA. [Graphical view]
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. msrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2G3P3_NOVAD

Accession

Primary (citable) accession number: Q2G3P3

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2006
Last sequence update:	March 21, 2006
Last modified:	May 1, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)