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Q2G302 (Q2G302_NOVAD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Saro_3336
OrganismNovosphingobium aromaticivorans (strain DSM 12444) [Complete proteome] [HAMAP]
Taxonomic identifier279238 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Novosphingobium

Protein attributes

Sequence length337 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2051Iron By similarity HAMAP MF_00323
Metal binding2881Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
Q2G302 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: 7AA54BB9E842672D

FASTA33736,918
        10         20         30         40         50         60 
MQRPADHPTV LTGKVGVLLV NLGTPDAPDA GAVKRYLKEF LSDRRVVEIP ALVWQPILRG 

        70         80         90        100        110        120 
IILNTRPRKS AHAYAQVWTD EGSPLAAITA AQARALQARL GESAIVRHAM RYQSPAMAKE 

       130        140        150        160        170        180 
LDALLQAGCE RILVAPLYPH YSGATTASAL DAVADWIKAR RRLPALRTLP PYHDDPAYIG 

       190        200        210        220        230        240 
ALHADLSRQI DALDFAPELL LLSYHGMPER TLHLGDPYHC HCRKTSRLLG ERFAQSNPAL 

       250        260        270        280        290        300 
RLETTFQSRF GKAKWLEPAT DAVLVDEARK GTRRIAIAAP GFSADCLETL EELAIRGKED 

       310        320        330 
FVAAGGTHFA SLACLNAGDD GMDMIEALVR RELSGWI

« Hide

References

[1]"Complete sequence of Novosphingobium aromaticivorans DSM 12444."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N. expand/collapse author list , Fredrickson J., Balkwill D., Romine M.F., Richardson P.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 12444.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000248 Genomic DNA. Translation: ABD27771.1.
RefSeqYP_498605.1. NC_007794.1.

3D structure databases

ProteinModelPortalQ2G302.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2G302.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3915983.
GenomeReviewsGene locus Saro_3336 in contig CP000248_GR.
KEGGnar:Saro_3336.
NMPDRfig|48935.1.peg.3854.
PATRIC22789550. VBINovAro50627_3426.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAIRPAKSA.
PhylomeDBQ2G302.
ProtClustDBCLSK844073.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2G302_NOVAD
AccessionPrimary (citable) accession number: Q2G302
Entry history
Integrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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