ID   LACA_STAA8              Reviewed;         142 AA.
AC   Q2G2R4; P26594;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   16-JUN-2009, entry version 20.
DE   RecName: Full=Galactose-6-phosphate isomerase subunit lacA;
DE            EC=5.3.1.26;
GN   Name=lacA; OrderedLocusNames=SAOUHSC_02455;
OS   Staphylococcus aureus (strain NCTC 8325).
OC   Bacteria; Firmicutes; Bacillales; Staphylococcus.
OX   NCBI_TaxID=93061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W.,
RA   Iandolo J.J.;
RT   "The Staphylococcus aureus NCTC8325 genome.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-63.
RX   MEDLINE=90299802; PubMed=2163387;
RA   Oskouian B., Stewart G.C.;
RT   "Repression and catabolite repression of the lactose operon of
RT   Staphylococcus aureus.";
RL   J. Bacteriol. 172:3804-3812(1990).
CC   -!- CATALYTIC ACTIVITY: D-galactose 6-phosphate = D-tagatose 6-
CC       phosphate.
CC   -!- PATHWAY: Carbohydrate metabolism; galactose degradation; D-
CC       tagatose 6-phosphate from D-galactose 6-phosphate: step 1/1.
CC   -!- SUBUNIT: Heteromultimeric protein consisting of lacA and lacB (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the lacAB/rpiB family.
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DR   EMBL; CP000253; ABD31475.1; -; Genomic_DNA.
DR   EMBL; M32103; AAA67855.1; -; Genomic_DNA.
DR   PIR; A38158; A38158.
DR   RefSeq; YP_500922.1; -.
DR   GeneID; 3919018; -.
DR   GenomeReviews; CP000253_GR; SAOUHSC_02455.
DR   KEGG; sao:SAOUHSC_02455; -.
DR   HOGENOM; Q2G2R4; -.
DR   OMA; Q2G2R4; SAMASNK.
DR   BioCyc; SAUR93061:SAOUHSC_02455-MON; -.
DR   GO; GO:0050044; F:galactose-6-phosphate isomerase activity; IEA:HAMAP.
DR   GO; GO:0019512; P:lactose catabolic process via tagatose-6-ph...; IEA:HAMAP.
DR   HAMAP; MF_01555; -; 1.
DR   InterPro; IPR004783; LacA.
DR   InterPro; IPR003500; Rib/Gal_isomrase.
DR   Gene3D; G3DSA:3.40.1400.10; Rib/Gal_isomrase; 1.
DR   Pfam; PF02502; LacAB_rpiB; 1.
DR   PIRSF; PIRSF005384; RpiB_LacA_B; 1.
DR   TIGRFAMs; TIGR01118; lacA; 1.
DR   TIGRFAMs; TIGR00689; rpiB_lacA_lacB; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Isomerase; Lactose metabolism.
FT   CHAIN         1    142       Galactose-6-phosphate isomerase subunit
FT                                lacA.
FT                                /FTId=PRO_0000247669.
SQ   SEQUENCE   142 AA;  15395 MW;  A52C4A7DBF30BE19 CRC64;
     MAIIIGSDEA GKRLKEVIKS YLLDNKYDVV DVTEGQEVDF VDATLAVAKD VQSQEGNLGI
     VIDAFGAGSF MVATKIKGMI AAEVSDERSG YMTRGHNNSR MITMGSEIVG DTLAKNVVKG
     FVEGKYDGGR HQIRVDMLNK MC
//