Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Uncharacterized protein

Gene

SAOUHSC_00107

Organism
Staphylococcus aureus (strain NCTC 8325)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi11 – 111Manganese 1Combined sources
Metal bindingi11 – 111ZincCombined sources
Metal bindingi13 – 131Manganese 1; via tele nitrogenCombined sources
Metal bindingi13 – 131Zinc; via tele nitrogenCombined sources
Metal bindingi56 – 561MagnesiumCombined sources
Metal bindingi56 – 561Manganese 1Combined sources
Metal bindingi56 – 561Manganese 2Combined sources
Metal bindingi56 – 561ZincCombined sources
Metal bindingi93 – 931MagnesiumCombined sources
Metal bindingi93 – 931Manganese 2Combined sources
Metal bindingi191 – 1911Magnesium; via tele nitrogenCombined sources
Metal bindingi191 – 1911Manganese 2; via tele nitrogenCombined sources
Metal bindingi231 – 2311Magnesium; via pros nitrogenCombined sources
Metal bindingi231 – 2311Manganese 2; via pros nitrogenCombined sources
Metal bindingi233 – 2331Manganese 1; via tele nitrogenCombined sources
Metal bindingi233 – 2331Zinc; via tele nitrogenCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Keywords - Ligandi

MagnesiumCombined sources, ManganeseCombined sources, Metal-bindingCombined sources, Nucleotide-bindingUniRule annotation, ZincCombined sources

Enzyme and pathway databases

BioCyciSAUR93061:GIWJ-101-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Ordered Locus Names:SAOUHSC_00107Imported
OrganismiStaphylococcus aureus (strain NCTC 8325)Imported
Taxonomic identifieri93061 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000008816 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi93061.SAOUHSC_00107.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3QFKX-ray2.05A2-511[»]
4Q7FX-ray1.98A2-511[»]
ProteinModelPortaliQ2G1L5.
SMRiQ2G1L5. Positions 2-511.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ2G1L5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 234229MetallophosInterPro annotationAdd
BLAST
Domaini313 – 4711595_nucleotid_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the 5'-nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CGH. Bacteria.
COG0737. LUCA.
HOGENOMiHOG000248801.
OMAiYYTSDVH.
OrthoDBiEOG696BW0.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
3.90.780.10. 1 hit.
InterProiIPR008334. 5'-Nucleotdase_C.
IPR006146. 5'-Nucleotdase_CS.
IPR006179. 5_nucleotidase/apyrase.
IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PANTHERiPTHR11575. PTHR11575. 2 hits.
PfamiPF02872. 5_nucleotid_C. 1 hit.
PF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR01607. APYRASEFAMLY.
SUPFAMiSSF55816. SSF55816. 1 hit.
SSF56300. SSF56300. 1 hit.
PROSITEiPS00786. 5_NUCLEOTIDASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2G1L5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNIAFYVVS DVHGYIFPTD FTSRNQYQPM GLLLANHVIE QDRRQYDQSF
60 70 80 90 100
KIDNGDFLQG SPFCNYLIAH SGSSQPLVDF YNRMAFDFGT LGNHEFNYGL
110 120 130 140 150
PYLKDTLRRL NYPVLCANIY ENDSTLTDNG VKYFQVGDQT VGVIGLTTQF
160 170 180 190 200
IPHWEQPEHI QSLTFHSAFE ILQQYLPEMK RHADIIVVCY HGGFEKDLES
210 220 230 240 250
GTPTEVLTGE NEGYAMLEAF SKDIDIFITG HQHRQIAERF KQTAVIQPGT
260 270 280 290 300
RGTTVGRVVL STDEYENLSV ESCELLPVID DSTFTIDEDD QHLRKQLEDW
310 320 330 340 350
LDYEITTLPY DMTINHAFEA RVAPHPFTNF MNYALLEKSD ADVACTALFD
360 370 380 390 400
SASGFKQVVT MRDVINNYPF PNTFKVLAVS GAKLKEAIER SAEYFDVKND
410 420 430 440 450
EVSVSADFLE PKPQHFNYDI YGGVSYTIHV GRPKGQRVSN MMIQGHAVDL
460 470 480 490 500
KQTYTICVNN YRAVGGGQYD MYIDAPVVKD IQVEGAQLLI DFLSNNNLMR
510
IPQVVDFKVE K
Length:511
Mass (Da):58,110
Last modified:March 21, 2006 - v1
Checksum:iE901F488CFA0DD69
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000253 Genomic DNA. Translation: ABD29288.1.
RefSeqiYP_498707.1. NC_007795.1.

Genome annotation databases

EnsemblBacteriaiABD29288; ABD29288; SAOUHSC_00107.
GeneIDi3919816.
KEGGisao:SAOUHSC_00107.
PATRICi19577840. VBIStaAur99865_0096.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000253 Genomic DNA. Translation: ABD29288.1.
RefSeqiYP_498707.1. NC_007795.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3QFKX-ray2.05A2-511[»]
4Q7FX-ray1.98A2-511[»]
ProteinModelPortaliQ2G1L5.
SMRiQ2G1L5. Positions 2-511.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi93061.SAOUHSC_00107.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD29288; ABD29288; SAOUHSC_00107.
GeneIDi3919816.
KEGGisao:SAOUHSC_00107.
PATRICi19577840. VBIStaAur99865_0096.

Phylogenomic databases

eggNOGiENOG4105CGH. Bacteria.
COG0737. LUCA.
HOGENOMiHOG000248801.
OMAiYYTSDVH.
OrthoDBiEOG696BW0.

Enzyme and pathway databases

BioCyciSAUR93061:GIWJ-101-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ2G1L5.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
3.90.780.10. 1 hit.
InterProiIPR008334. 5'-Nucleotdase_C.
IPR006146. 5'-Nucleotdase_CS.
IPR006179. 5_nucleotidase/apyrase.
IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PANTHERiPTHR11575. PTHR11575. 2 hits.
PfamiPF02872. 5_nucleotid_C. 1 hit.
PF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR01607. APYRASEFAMLY.
SUPFAMiSSF55816. SSF55816. 1 hit.
SSF56300. SSF56300. 1 hit.
PROSITEiPS00786. 5_NUCLEOTIDASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The Staphylococcus aureus NCTC 8325 genome."
    Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.
    (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.); Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington D.C (2006)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCTC 8325Imported.
  2. "2.05 Angstrom Crystal Structure of Putative 5'-Nucleotidase from Staphylococcus aureus in complex with alpha-ketoglutarate."
    Center for Structural Genomics of Infectious Diseases (CSGID)
    Minasov G., Wawrzak Z., Krishna S.N., Halavaty A., Shuvalova L., Dubrovska I., Winsor J., Kiryukhina O., Bagnoli F., Falugi F., Bottomley M., Grandi G., Anderson W.F.
    Submitted (JAN-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS) OF 2-511 IN COMPLEX WITH MANGANESE AND ZINC.
  3. "1.98 Angstrom Crystal Structure of Putative 5'-Nucleotidase from Staphylococcus aureus in complex with Adenosine."
    Center for Structural Genomics of Infectious Diseases (CSGID)
    Minasov G., Nocadello S., Shuvalova L., Dubrovska I., Winsor J., Bagnoli F., Falugi F., Bottomley M., Grandi G., Anderson W.F.
    Submitted (APR-2014) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.98 ANGSTROMS) OF 2-511 IN COMPLEX WITH MAGNESIUM AND MANGANESE.

Entry informationi

Entry nameiQ2G1L5_STAA8
AccessioniPrimary (citable) accession number: Q2G1L5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: July 6, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.