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Q2G1J0 (ALDA_STAA8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative aldehyde dehydrogenase AldA
EC=1.2.1.3
Gene names
Name:aldA
Ordered Locus Names:SAOUHSC_00132
OrganismStaphylococcus aureus (strain NCTC 8325)
Taxonomic identifier93061 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length495 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular functionaldehyde dehydrogenase (NAD) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 495495Putative aldehyde dehydrogenase AldA
PRO_0000290788

Regions

Nucleotide binding212 – 2187NAD By similarity

Sites

Active site2561 By similarity
Active site2901 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2G1J0 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: DCBE4F433645A52A

FASTA49553,659
        10         20         30         40         50         60 
MAVNVRDYIA ENYGLFINGE FVKGSSDETI EVTNPATGET LSHITRAKDK DVDHAVKVAQ 

        70         80         90        100        110        120 
EAFESWSLTS KSERAQMLRD IGDKLMAQKD KIAMIETLNN GKPIRETTAI DIPFAARHFH 

       130        140        150        160        170        180 
YFASVIETEE GTVNDIDKDT MSIVRHEPIG VVGAVVAWNF PMLLAAWKIA PAIAAGNTIV 

       190        200        210        220        230        240 
IQPSSSTPLS LLEVAKIFQE VLPKGVVNIL TGKGSESGNA IFNHDGVDKL SFTGSTDVGY 

       250        260        270        280        290        300 
QVAEAAAKHL VPATLELGGK SANIILDDAN LDLAVEGIQL GILFNQGEVC SAGSRLLVHE 

       310        320        330        340        350        360 
KIYDQLVPRL QEAFSNIKVG NPQDEATQMG SQTGKDQLDK IQSYIDAAKE SDAQILAGGH 

       370        380        390        400        410        420 
RLTENGLDKG FFFEPTLIAV PDNHHKLAQE EIFGPVLTVI KVKDDQEAID IANDSEYGLA 

       430        440        450        460        470        480 
GGVFSQNITR ALNIAKAVRT GRIWINTYNQ VPEGAPFGGY KKSGIGRETY KGALSNYQQV 

       490 
KNIYIDTSNA LKGLY

« Hide

References

[1]"The Staphylococcus aureus NCTC8325 genome."
Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCTC 8325.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000253 Genomic DNA. Translation: ABD29313.1.
RefSeqYP_498732.1. NC_007795.1.

3D structure databases

HSSPHSSP built from PDB template 2D4E based on UniProtKB Q5SJP9.
ProteinModelPortalQ2G1J0.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2G1J0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000028164; EBSTAP00000027115; EBSTAG00000028163.
GeneID3919841.
GenomeReviewsGene locus SAOUHSC_00132 in contig CP000253_GR.
KEGGsao:SAOUHSC_00132.
PATRIC19577896. VBIStaAur99865_0124.

Phylogenomic databases

eggNOGCOG1012.
GeneTreeEBGT00050000023967.
HOGENOMHBG752218.
OMAIFNHEGV.
PhylomeDBQ2G1J0.
ProtClustDBCLSK884447.

Enzyme and pathway databases

BioCycSAUR93061:SAOUHSC_00132-MONOMER.

Family and domain databases

InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK00128.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALDA_STAA8
AccessionPrimary (citable) accession number: Q2G1J0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: March 21, 2006
Last modified: January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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