ID   NANE_STAA8              Reviewed;         222 AA.
AC   Q2G157;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   16-JUN-2009, entry version 21.
DE   RecName: Full=Putative N-acetylmannosamine-6-phosphate 2-epimerase;
DE            EC=5.1.3.9;
DE   AltName: Full=ManNAc-6-P epimerase;
GN   Name=nanE; OrderedLocusNames=SAOUHSC_00298;
OS   Staphylococcus aureus (strain NCTC 8325).
OC   Bacteria; Firmicutes; Bacillales; Staphylococcus.
OX   NCBI_TaxID=93061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W.,
RA   Iandolo J.J.;
RT   "The Staphylococcus aureus NCTC8325 genome.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to
CC       N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential).
CC   -!- CATALYTIC ACTIVITY: N-acyl-D-glucosamine 6-phosphate = N-acyl-D-
CC       mannosamine 6-phosphate.
CC   -!- PATHWAY: Amino-sugar metabolism; N-acetylneuraminic acid
CC       degradation; D-fructose 6-phosphate from N-acetylneuraminic acid:
CC       step 3/5.
CC   -!- SIMILARITY: Belongs to the nanE family.
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DR   EMBL; CP000253; ABD29467.1; -; Genomic_DNA.
DR   RefSeq; YP_498888.1; -.
DR   SMR; Q2G157; 1-221.
DR   GeneID; 3919525; -.
DR   GenomeReviews; CP000253_GR; SAOUHSC_00298.
DR   KEGG; sao:SAOUHSC_00298; -.
DR   HOGENOM; Q2G157; -.
DR   OMA; Q2G157; YNTPELA.
DR   BioCyc; SAUR93061:SAOUHSC_00298-MON; -.
DR   GO; GO:0047465; F:N-acylglucosamine-6-phosphate 2-epimerase a...; IEA:EC.
DR   GO; GO:0006051; P:N-acetylmannosamine metabolic process; IEA:HAMAP.
DR   HAMAP; MF_01235; -; 1.
DR   InterPro; IPR007260; NanE.
DR   Pfam; PF04131; NanE; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Complete proteome; Isomerase.
FT   CHAIN         1    222       Putative N-acetylmannosamine-6-phosphate
FT                                2-epimerase.
FT                                /FTId=PRO_0000301485.
SQ   SEQUENCE   222 AA;  24545 MW;  7417D8DD1A48A041 CRC64;
     MLPHGLIVSC QALPDEPLHS SFIMSKMALA AYEGGAVGIR ANTKEDILAI KETVDLPVIG
     IVKRDYDHSD VFITATSKEV DELIESQCEV IALDATLQQR PKETLDELVS YIRTHAPNVE
     IMADIATVEE AKNAARLGFD YIGTTLHGYT SYTQGQLLYQ NDFQFLKDVL QSVDAKVIAE
     GNVITPDMYK RVMDLGVHCS VVGGAITRPK EITKRFVQIM ED
//