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Protein

Probable quinol oxidase subunit 3

Gene

qoxC

Organism
Staphylococcus aureus (strain NCTC 8325)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.By similarity

Catalytic activityi

Ubiquinol-8 + O2 = Ubiquinone-8 + H2O.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciSAUR93061:GIWJ-965-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable quinol oxidase subunit 3 (EC:1.10.3.-)
Alternative name(s):
Quinol oxidase polypeptide III
Gene namesi
Name:qoxC
Ordered Locus Names:SAOUHSC_01000
OrganismiStaphylococcus aureus (strain NCTC 8325)
Taxonomic identifieri93061 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000008816 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei20 – 4021HelicalSequence analysisAdd
BLAST
Transmembranei62 – 8221HelicalSequence analysisAdd
BLAST
Transmembranei91 – 11121HelicalSequence analysisAdd
BLAST
Transmembranei133 – 15321HelicalSequence analysisAdd
BLAST
Transmembranei172 – 19221HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 201201Probable quinol oxidase subunit 3PRO_0000275891Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi93061.SAOUHSC_01000.

Structurei

3D structure databases

ProteinModelPortaliQ2FZK1.
SMRiQ2FZK1. Positions 20-196.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CCU. Bacteria.
COG1845. LUCA.
HOGENOMiHOG000086398.
KOiK02828.
OMAiYTELVKH.
OrthoDBiEOG6SFPBZ.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
IPR014246. QoxC.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
TIGRFAMsiTIGR02897. QoxC. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2FZK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHDTNTIDS RTHEGELNKL GFWIFITAEF ALFGTLFATL LTLQHGGDYA
60 70 80 90 100
GKMTTELFEL PLVLIMTFAL LFSSYTCGIA IYYMRQEKQK LMMFWMIITL
110 120 130 140 150
LLGLVFVGFE IYEFAHYASE GVNPTIGSYW SSFFILLGTH GCHVSLGIVW
160 170 180 190 200
AICLLIQIQR RGLDKYNAPK LFIVSLYWHF LDVVWVFIFT AVYMIGMVYS

G
Length:201
Mass (Da):23,057
Last modified:March 21, 2006 - v1
Checksum:i0DBD36DE9ED6E758
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000253 Genomic DNA. Translation: ABD30124.1.
RefSeqiYP_499552.1. NC_007795.1.

Genome annotation databases

EnsemblBacteriaiABD30124; ABD30124; SAOUHSC_01000.
GeneIDi3920400.
KEGGisao:SAOUHSC_01000.
PATRICi19579519. VBIStaAur99865_0918.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000253 Genomic DNA. Translation: ABD30124.1.
RefSeqiYP_499552.1. NC_007795.1.

3D structure databases

ProteinModelPortaliQ2FZK1.
SMRiQ2FZK1. Positions 20-196.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi93061.SAOUHSC_01000.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD30124; ABD30124; SAOUHSC_01000.
GeneIDi3920400.
KEGGisao:SAOUHSC_01000.
PATRICi19579519. VBIStaAur99865_0918.

Phylogenomic databases

eggNOGiENOG4105CCU. Bacteria.
COG1845. LUCA.
HOGENOMiHOG000086398.
KOiK02828.
OMAiYTELVKH.
OrthoDBiEOG6SFPBZ.

Enzyme and pathway databases

BioCyciSAUR93061:GIWJ-965-MONOMER.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
IPR014246. QoxC.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
TIGRFAMsiTIGR02897. QoxC. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The Staphylococcus aureus NCTC 8325 genome."
    Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.
    (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.); Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington D.C. (2006)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCTC 8325.

Entry informationi

Entry nameiQOX3_STAA8
AccessioniPrimary (citable) accession number: Q2FZK1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: March 21, 2006
Last modified: July 6, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.