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Protein

Aminomethyltransferase

Gene

gcvT

Organism
Staphylococcus aureus (strain NCTC 8325)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine.UniRule annotation

Catalytic activityi

[Protein]-S8-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase

Enzyme and pathway databases

BioCyciSAUR93061:G1G5Y-1520-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
AminomethyltransferaseUniRule annotation (EC:2.1.2.10UniRule annotation)
Alternative name(s):
Glycine cleavage system T proteinUniRule annotation
Gene namesi
Name:gcvTUniRule annotation
Ordered Locus Names:SAOUHSC_01634
OrganismiStaphylococcus aureus (strain NCTC 8325)
Taxonomic identifieri93061 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000008816 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000477151 – 363AminomethyltransferaseAdd BLAST363

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H.UniRule annotation

Protein-protein interaction databases

STRINGi93061.SAOUHSC_01634

Structurei

3D structure databases

ProteinModelPortaliQ2FY33
SMRiQ2FY33
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvT family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D43 Bacteria
COG0404 LUCA
HOGENOMiHOG000239381
KOiK00605
OMAiMPVQYPA

Family and domain databases

Gene3Di3.30.1360.120, 2 hits
HAMAPiMF_00259 GcvT, 1 hit
InterProiView protein in InterPro
IPR006223 GCS_T
IPR022903 GCS_T_bac
IPR028896 GCST/YgfZ/DmdA
IPR013977 GCV_T_C
IPR006222 GCV_T_N
IPR029043 GcvT/YgfZ_C
IPR027266 TrmE/GcvT_dom1
PfamiView protein in Pfam
PF01571 GCV_T, 1 hit
PF08669 GCV_T_C, 1 hit
PIRSFiPIRSF006487 GcvT, 1 hit
SUPFAMiSSF101790 SSF101790, 1 hit
TIGRFAMsiTIGR00528 gcvT, 1 hit

Sequencei

Sequence statusi: Complete.

Q2FY33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSDLKQTPL YQNYVDRGAK IVEFGGWAMP VQFSSIKEEH NAVRYEIGLF
60 70 80 90 100
DVSHMGEIEV TGKDASQFVQ YLLSNDTDNL TTSKALYTAL CNEEGGIIDD
110 120 130 140 150
LVIYKLADDN YLLVVNAANT EKDFNWILKH KEKFDVEVQN VSNQYGQLAI
160 170 180 190 200
QGPKARDLIN QLVDEDVTEM KMFEFKQGVK LFGANVILSQ SGYTGEDGFE
210 220 230 240 250
IYCNIDDTEK IWDGLLEYNV MPCGLGARDT LRLEAGLPLH GQDLTESITP
260 270 280 290 300
YEGGIAFASK PLIDADFIGK SVLKDQKENG APRRTVGLEL LEKGIARTGY
310 320 330 340 350
EVMDLDGNII GEVTSGTQSP SSGKSIALAM IKRDEFEMGR ELLVQVRKRQ
360
LKAKIVKKNQ IDK
Length:363
Mass (Da):40,458
Last modified:March 21, 2006 - v1
Checksum:iC70F4B160FFD6CBE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000253 Genomic DNA Translation: ABD30711.1
RefSeqiWP_000093349.1, NC_007795.1
YP_500147.1, NC_007795.1

Genome annotation databases

EnsemblBacteriaiABD30711; ABD30711; SAOUHSC_01634
GeneIDi3919971
KEGGisao:SAOUHSC_01634
PATRICifig|93061.5.peg.1487

Similar proteinsi

Entry informationi

Entry nameiGCST_STAA8
AccessioniPrimary (citable) accession number: Q2FY33
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 21, 2006
Last modified: March 28, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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