Reviewed,
UniProtKB/Swiss-Prot Q2FXL7 (DHA2_STAA8)
Last modified
February 9, 2010.
Version 29.
History...
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90%,
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Alanine dehydrogenase 2 EC=1.4.1.1 | ||||
| Gene names |
| ||||
| Organism | Staphylococcus aureus (strain NCTC 8325) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 93061 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Staphylococcus |
Protein attributes
| Sequence length | 372 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer By similarity. |
| Catalytic activity | L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. |
| Pathway | |
| Sequence similarities | Belongs to the AlaDH/PNT family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | alanine dehydrogenase activity Inferred from electronic annotation. Source: EC bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "The Staphylococcus aureus NCTC8325 genome." Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J. Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000253 Genomic DNA. Translation: ABD30886.1. |
| RefSeq | YP_500323.1. |
3D structure databases | |
| SMR | Q2FXL7. Positions 1-371. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q2FXL7. |
Genome annotation databases | |
| GeneID | 3919288. |
| GenomeReviews | Gene locus SAOUHSC_01818 in contig CP000253_GR. |
| KEGG | sao:SAOUHSC_01818. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0686. |
| HOGENOM | HBG289735. |
| OMA | VAHGHEV. |
Enzyme and pathway databases | |
| BioCyc | SAUR93061:SAOUHSC_01818-MONOMER. |
Family and domain databases | |
| InterPro | IPR007698. Ala_DH/PNT_C. IPR008142. Ala_DH/PNT_CS1. IPR008143. Ala_DH/PNT_CS2. IPR007886. Ala_DH/PNT_N. IPR008141. Ala_DH/Pyr_transHydgase. IPR016040. NAD(P)-bd_dom. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| Pfam | PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00518. alaDH. 1 hit. |
| PROSITE | PS00836. ALADH_PNT_1. 1 hit. PS00837. ALADH_PNT_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | DHA2_STAA8 | ||||||||
| Accession | Primary (citable) accession number: Q2FXL7 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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